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Recent News and Articles on the Keywords: blood + heart + transfusions  Related to the article below (Last Update: 8/4/2008)

Mediware Reaches Milestone Multi-Site System Implementation
CNNMoney.com -
Because WFH's organization includes both a centralized transfusion service (CTS) and hospital-based blood banks, it needed a system with multi-facility ...
Blood disorder boy needs help
Malaysia Star, Malaysia - Aug 1, 2008
The excess iron in his body, a result of the frequent blood transfusion, has also started to take its toll on his heart, liver and endocrine glands, ...

Sunday Times.lk
Whose hands have blood on them?
Sunday Times.lk, Sri Lanka - Aug 2, 2008
Pix by MA Pushpa Kumara Did the National Blood Centre, the heart of the National Blood Transfusion Service in the country, use expired kits to get platelets ...
Summer Months = Low Blood Supply
KPSP, CA - Aug 2, 2008
Today most sophisticated medical care such as transplants, heart surgeries and cancer surgeries rely on blood transfusions.

ABC News
Doctors Work Inside Mother's Womb to Save Twins
ABC News - Jul 29, 2008
The twins were diagnosed with "Twin-to-Twin Transfusion Syndrome," which affects about 2000 pregnancies every year. For reasons that are unclear, the blood ...
Red Cross seeks minority donors
Youngstown Vindicator, OH - Jul 31, 2008
These types of illnesses often require blood transfusions for treatment or survival. Many ethnic minority groups have rare blood types that are distinctive ...

Los Angeles Times
Dr. Michael E. DeBakey, 99; preeminent cardiac surgeon saved ...
Los Angeles Times, CA - Jul 13, 2008
That device, in which the pump components never touched the fluid, was quickly adapted for use in blood transfusions and other applications. ...
Michael DeBakey Telegraph.co.uk
Famed Heart Surgeon Michael DeBakey Dies at 99 TruthNews.com
Surgical maestro DeBakey dies at age 99 TheHeart.Org
AlterNet - PRESS TV
all 1,370 news articles »
Is blood transfusion necessary?
Sun.Star, Philippines - Jul 21, 2008
A 2004 study of people suffering from acute coronary syndrome (a specific type of heart attack) concluded that unnecessary blood transfusions "might be ...
?Eagle? to land at Saint Mary?s
Russellville Courier, AR - Jul 28, 2008
And while not all cancer patients need blood transfusions, at least one study has found the need for transfusions in oncology to have increased by as much ...
Pastor leaves impression on community
Frederick News Post (subscription), MD -
In April, when she needed multiple blood transfusions, her congregation took it upon themselves to lend a hand. One member, Doug Smith, took the idea for a ...
Source: Google News

Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. -
D Royston, BP Bidstrup, KM Taylor, RN Sapsford - Lancet, 1987 - ncbi.nlm.nih.gov
1987 Dec 5;2(8571):1289-91. Effect of aprotinin on need for blood transfusion after
repeat open-heart surgery. Royston D, Bidstrup BP, Taylor KM, Sapsford RN. ...

… -associated non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study Group -
LB Seeff, Z Buskell-Bales, EC Wright, SJ Durako, … - New Engl J Med, 1992 - content.nejm.org
... New England Journal of Medicine -- Long-term mortality after transfusion-associated
non-A, non-B hepatitis. The National Heart, Lung, and Blood Institute Study ...

… postoperative blood loss and transfusion requirement after beating-heart coronary operations: A … -
R Ascione, S Williams, CT Lloyd, T Sundaramoorthi, … - The Journal of Thoracic and Cardiovascular Surgery, 2001 - AATS/WTSA
... Sundaramoorthi, coronary operations: A prospective randomized study Reduced
postoperative blood loss and transfusion requirement after beating-heart ...

… non-A, non-B, and type C hepatitis: A National Heart, Lung, and Blood Institute collaborative study -
L Seeff? - Hepatology, 2001 - doi.wiley.com
Long-Term Mortality and Morbidity of Transfusion-Associated Non-A, Non-B, and Type
C Hepatitis: A National Heart, Lung, and Blood Institute Collaborative Study ...

Avoidance of allogeneic blood transfusions by treatment with epoetin beta (recombinant human … -
O Sowade, H Warnke, P Scigalla, B Sowade, W Franke … - Blood, 1997 - ncbi.nlm.nih.gov
... allogeneic blood transfusions (ABT) and the associated risks in patients undergoing
primary elective open-heart surgery and in whom autologous blood donation ...

… and completely HLA-DR-mismatched blood transfusions on survival of heart and kidney allografts -
EL Lagaaij, IP Hennemann, M Ruigrok, MW de Haan, … - New England Journal of Medicine, 1989 - content.nejm.org
... The New England Journal of Medicine -- Effect of one-HLA-DR-antigen-matched and
completely HLA-DR-mismatched blood transfusions on survival of heart and kidney ...

Open heart operations without transfusion using a multimodality blood conservation strategy in 50 … -
TK Rosengart, RE Helm, WJ DeBois, N Garcia, KH … - J Am Coll Surg, 1997 - ncbi.nlm.nih.gov
Open heart operations without transfusion using a multimodality blood conservation
strategy in 50 Jehovah's Witness patients: implications for a "bloodless ...

Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: … -
GJ Despotis - Anesthesia & Analgesia, 1996 - IARS
... and C. Ramamoorthy Factors Associated with Blood Loss and Blood Product Transfusions:
A Multivariate Analysis in Children After Open-Heart Surgery Anesth. ...

Relationship of Blood Transfusion and Clinical Outcomes in Patients With Acute Coronary Syndromes -
SV Rao, JG Jollis, RA Harrington, CB Granger, LK … - JAMA, 2004 - Am Med Assoc
... This suggests that a hematocrit as low as 25% may be tolerated without blood
transfusion in otherwise stable patients with ischemic heart disease. ...

blood transfusion-induced tolerance in adult rats with a dominant TCR-Vbeta rearrangement in heart -
P Douillard - The Journal of Immunology, 1996 - Am Assoc Immnol
... the TCR Vbeta chain diversity of T cells infiltrating rejected and tolerated heart
allografts in a model of donor-specific blood transfusion-induced tolerance ...

Source: Google Scholar
 
 

Blood Transfusions Won't Help All Heart Patients

November 15, 2006 03:58:03 PM PST

WEDNESDAY, Nov. 15 (HealthDay News) -- Blood transfusions can benefit some patients with acute coronary syndrome but will harm others and should be used in moderation, U.S. researchers report.

Acute coronary syndrome (ACS) is a condition in which patients show signs of a heart attack.

The findings support previous research that suggests that doctors should reconsider how they make decisions about which ACS patients should get transfusions, said lead investigator Dr. Karen Alexander of Duke University in Durham, N.C.

For this study, involving more than 44,000 patients, Alexander's team focused on a key blood measure (hematocrit) to see when doctors made the decision to give a patient a transfusion. They then compared this transfusion "decision point" to patient outcomes.

Hematocrit represents the percentage of oxygen-carrying red blood cells in blood. Normal hematocrit is 42 percent to 52 percent in men and 36 percent to 48 percent for women.

This study found that transfusions were most beneficial in patients whose lowest recorded hematrocrit level was less than 24 percent, but were associated with harm in patients whose lowest recorded hematocrit levels were higher than 30 percent. In patients with hematocrit levels that bottomed out at between 24 percent and 30 percent, transfusions caused no harm or benefit, the researchers said.

Article continues below and (thank you)

 

"Providers may want to reconsider how they decide which patients should get transfusions," Alexander said. "Our data confirms no harm or benefit in the medium range of 24 percent to 30 percent, so in this group of patients, it might be best to wait and see if the hematocrit drops farther before making the decision to transfuse. Given the scarcity of the blood supply, we certainly want to apply this therapy to those who stand to benefit the most while at the same time avoiding harm."

The study was to be presented Wednesday at the American Heart Association's annual meeting in Chicago.

More information

The American Heart Association has more about acute coronary syndrome.

 

Antibiotics Are Useless for Most Cases of Bronchitis

November 15, 2006 03:58:03 PM PST
By Ed Edelson
HealthDay Reporter

WEDNESDAY, Nov. 15 (HealthDay News) -- Most people who go to a doctor with the raspy breathing problem called bronchitis get an antibiotic. Most of them shouldn't, a new study contends.

Two physicians at the Virginia Commonwealth University School of Medicine surveyed the world literature on bronchitis -- research studies, clinical trials and anything related to bronchitis and its treatment.

"Physicians should be encouraged to avoid antibiotics in most cases," said Dr. Richard P. Wenzel, chairman of the department of internal medicine at Virginia Commonwealth and one of the authors of the report.

The findings are published in the Nov. 16 issue of the New England Journal of Medicine.

The primary reason for over-prescription of antibiotics is that most cases of bronchitis, which is inflammation of the tiny airways of the lungs, "are caused by agents for which we have no therapy yet," meaning viruses, Wenzel said. Only a small percentage of acute bronchitis cases are caused by bacteria that doctors can treat, such as whooping cough, he said.

Yet doctors keep prescribing antibiotics, he said. He estimated that 70 percent to 80 percent of bronchitis patients are given a course of antibiotics lasting five to 10 days.

That's a lot of antibiotics. One of every 20 American adults will get bronchitis in a given year, Wenzel said. A first reason for them not taking antibiotics is that the drugs cost money, in an era when the mounting cost of health care is a major concern, he said.

"And all antibiotics have side effects, such as rash, diarrhea and abdominal pain," Wenzel said. Side effects are acceptable only when a medication helps the patient, he said.

"The third reason for not prescribing antibiotics is the impressive pressure it puts on organisms to select more resistant strains, so that the ones we use will no longer be effective," Wenzel said. While economists worry about medical costs, physicians worry about antibiotic-resistant strains of bacteria.

With all those arguments against the practice, why do doctors still write those prescriptions?

One reason is convenience, Wenzel said. "Think of all the patients we have to move through the office," he said. "I could take 15 minutes to explain why an antibiotic is not needed or write a prescription in 30 seconds."

And bronchitis tends to be overlooked as a subject of medical interest, Wenzel said. "It isn't considered very jazzy," he said. "It doesn't get highlights in medical journals or educational conferences. I can't remember in the past 10 years hearing a speaker discuss bronchitis at a medical meeting."

The information on bronchitis is there for any doctor who cares to look. The American Academy of Family Physicians notes that "because acute bronchitis is usually caused by viruses, antibiotics... usually do not help." The academy recommends getting lots of rest, drinking lots of non-caffeinated fluids, keeping the indoor humidity high and waiting for the condition to go away "after a few days or a week." If coughing and other symptoms persist, it could be a sign of a more serious condition, such as asthma or pneumonia.

One big reason for antibiotic prescriptions is patient demand, said Dr. Jeffrey Chapman, director of interstitial lung disease at the Cleveland Clinic.

"But patients are getting more savvy," he said. "They understand that a lot of infections are viral and that giving them an antibiotic places them at risk."

People with the bothersome symptoms of bronchitis shouldn't insist on a prescription, Chapman said. They should understand that "it may be the best course of treatment not to give an antibiotic."

"The message is getting out, a little bit at a time," he said. "There is a better understanding than there was, say, 10 years ago, that sometimes an antibiotic is not the better treatment."

More information

For more on bronchitis and its treatment, visit the American Academy of Family Physicians.

 
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