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Recent News and Articles on the Keywords: fracture risk + long-term fracture + bone  Related to the article below (Last Update: 5/13/2008)

Diabetes Drugs May Be Related To Fracture Risk
Science Daily (press release) - Apr 28, 2008
The odds for fracture were increased among patients who took the drugs for approximately 12 to 18 months and the risk was highest for those with two or more ...
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Insider Medicine
Diabetes drug 'can double risk of fractures'
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More Evidence of Increased Fractures With Thiazolidinediones
Medscape (subscription) - May 5, 2008
They note that patients with type 2 diabetes have higher bone density than normal and thus might be expected to be at lower risk for fracture, ...

Vancouver Sun
New Worries Over Blockbuster Meds Avandia, Fosamax
U.S. News & World Report, DC - Apr 28, 2008
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Study: Impact Exercise Increases Bone Mass, Decreases Fracture Risk
PhysOrg.com, VA - Apr 17, 2008
If the benefits persist into adulthood this may reduce their fracture risk as adults as much as 25 percent. The studies, which will be published in ...
LegalView Updates Avandia Portal with Details of Conclusive
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eFluxMedia
Heart Failure Drugs Linked to Hip Bone Loss in Older Men
Washington Post, United States - Apr 15, 2008
But the researchers said there's been "uncertainty as to whether this increased fracture risk is attributable to negative effects on bone mineral density, ...
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Men need bone tests as well as women
TamilStar.com, Sri Lanka - Apr 14, 2008
It used the FRAX predictions to update guidelines on who needs bone-density testing, and to calculate when fracture risk becomes high enough that ...
Stand tall
7DAYS, United Arab Emirates - May 1, 2008
Up to 30 per cent of patients suffering a hip fracture will require long term nursing home care, while some 20 per cent of women with a hip fracture will ...
GE Healthcare Helping Women Lead Healthier Lives, Showcasing ...
Medical News Today (press release), UK - May 7, 2008
How many women have osteoporosis? J Bone Miner Res 7:1005. 3. Kanis JA, Johnell O, Oden A, et al. (2000) Long-term risk of osteoporotic fracture in Malmo. ...
Source: Google News

Long-term fracture prediction by bone mineral assessed at different skeletal sites. -
LJ Melton 3rd, EJ Atkinson, WM O'Fallon, HW Wahner … - J Bone Miner Res, 1993 - ncbi.nlm.nih.gov
Long-term fracture prediction by bone mineral assessed at different skeletal ... in lumbar
spine BMD increased the risk of a new vertebral fracture comparably to ...

Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With … -
B Ettinger, DM Black, BH Mitlak, RK Knickerbocker, … - JAMA, 1999 - Am Med Assoc
... 1 However, the effect of raloxifene on the risk of fracture is not known. ... studies
in postmenopausal women have suggested that long-term estrogen therapy ...

Diagnosis of osteoporosis and assessment of fracture risk -
JA Kanis - The Lancet, 2002 - Elsevier
... Presence of strong risk factors. Oestrogen status. ... Long-term secondary amenorrhoea
(>1 year). Primary hypogonadism. ... Maternal family history of hip fracture. ...

Long-Term Risk of Osteoporotic Fracture in Malm? -
JA Kanis, O Johnell, A Oden, I Sernbo, I Redlund- … - Osteoporosis International, 2000 - Springer
... Long-Term Risk of Osteoporotic Fracture in Malmo? ... 1 WHO Collaborating Centre for
Metabolic Bone Diseases, University of Shef?eld Medical School ...

… Month Changes in Bone Turnover are Related to Reduction in Vertebral Fracture Risk During 3 Years … -
NH Bjarnason, S Sarkar, T Duong, B Mitlak, PD … - Osteoporosis International, 2001 - Springer
... there was no association between change in BMD and long- term fracture risk. Future
studies should investigate strategies for using bone turnover markers in ...

Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate -
R EASTELL, I BARTON, RA HANNON, A CHINES, P GARNERO … - Journal of Bone and Mineral Research, 2003 - Am Soc Bone Min Res
... the early decrease in bone turnover is related to the long-term increase in BMD, (
15 ) but a potential association with vertebral fracture risk has not been ...

Bone Density and Fracture Risk in Men -
LJ MELTON III, EJ ATKINSON, MK O'CONNOR, WM O' … - Journal of Bone and Mineral Research, 1998 - Am Soc Bone Min Res
... (2005) Evaluation of a Prediction Model for Long-Term Fracture Risk. Journal of
Bone and Mineral Research 20:4, 551-556 Online publication date: 1-Apr-2005. ...

Risk of vertebral fracture and relationship to bone mineral density in steroid treated rheumatoid … -
NF Peel, DJ Moore, NA Barrington, DE Bax, R … - British Medical Journal, 1995 - ard.bmj.com
... and PN Sambrook Vertebral Fracture Risk With Long-term Corticosteroid Therapy:
Prevalence and Relation to Age, Bone Density, and Corticosteroid Use Archives of ...

Vertebral Fracture Risk With Long-term Corticosteroid Therapy Prevalence and Relation to Age, Bone … -
V Naganathan, G Jones, P Nash, G Nicholson, J … - Archives of Internal Medicine, 2000 - Am Med Assoc
... are available regarding vertebral fracture risk in patients ... and the role of risk
factors such ... deformity in patients receiving long-term corticosteroid therapy. ...

Bone mineral density and the risk of fracture in patients receiving long-term inhaled steroid … -
JH Toogood, JC Baskerville, AE Markov, AB Hodsman, … - J Allergy Clin Immunol, 1995 - ncbi.nlm.nih.gov
1995 Aug;96(2):157-66. Click here to read Bone mineral density and the risk of fracture
in patients receiving long-term inhaled steroid therapy for asthma. ...

Source: Google Scholar

Bone test predicts long-term fracture risk

Last Updated: 2007-12-20 16:54:17 -0400 (Reuters Health)

NEW YORK (Reuters Health) - A single test of bone thickness can predict whether a woman is likely to experience backbone or "vertebral" fractures in the next 15 years, according to a report in the Journal of the American Medical Association.

Bone mineral density (BMD) is a measure of bone thickness that can be determined with special X-rays and ultrasound. Osteoporosis, which is characterized by a low BMD, is a common disorder among older women.

Women with low BMD who already have vertebral fracture are known to be at risk of new vertebral fractures during short-term follow-up, Dr. Jane A. Cauley, at the University of Pittsburgh, and her associates note, but the long-term risk had not been established.

Their current analysis included 2,680 white women enrolled in the Study of Osteoporotic Fractures. The average patient age when the study began was 68.8 years and 394 of the subjects had X-ray evidence of at least one vertebral fracture.

During 15 years of follow-up, 42.4 percent of women with a prior vertebral fracture developed a new one, much higher than the 14.2 percent rate seen among women who had never had these fractures.

After accounting for hormone use and other factors, the risk of a new vertebral fracture was increased fourfold among those with vertebral fractures when the study began.

Low BMD at any body site also predicted new fractures, but BMD at the lumbar spine had the strongest association.

"The absolute risk of vertebral fractures was more than 50 percent among women with both a (prior) vertebral fracture and BMD in the osteoporotic range," the investigators report. For those with neither risk factor, the risk was about 9 percent.

"Our results support the recommendation that older women with a (prior) vertebral fracture should be treated for osteoporosis irrespective of BMD," Cauley and her associates conclude.

SOURCE: Journal of the American Medical Association, December 19, 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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