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Recent News and Articles on the Keywords: sibutramine may + may help + sibutramine  Related to the article below (Last Update: 5/5/2008)

Don't expect a pill to make you thin
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Source: Google News

Effect of Sibutramine on Weight Management and Metabolic Control in Type 2 Diabetes: A meta-analysis … -
R Vettor, R Serra, R Fabris, C Pagano, G Federspil - Diabetes Care, 2005 - Am Diabetes Assoc
... of other risk factors. Sibutramine may help improve glucose control because
it is conducive to weight loss. The reviewed data on ...

A double-blind randomized placebo-controlled trial of sibutramine -
GA Bray - Obesity Research, 1996 - NAASO
... group treated with the highest dose. These studies suggest that sibutramine
may be a valuable new drug for treatment of obesity. ...

The Efficacy and Safety of Sibutramine for Weight Loss A Systematic Review -
DE Arterburn, PK Crane, DL Veenstra - Archives of Internal Medicine, 2004 - Am Med Assoc
... Introduced in 1997, sibutramine hydrochloride is a relatively new agent for weight ...
is a norepinephrine and serotonin reuptake inhibitor that may also stimulate ...

A double-blind, placebo-controlled trial of sibutramine for clozapine-associated weight gain -
DC Henderson, X Fan, PM Copeland, CP Borba, TB … - Acta Psychiatrica Scandinavica, 2007 - Blackwell Synergy
... However, it is possible, with a larger sample size, that sibutramine may
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Obesity drug sibutramine (Meridia): hypertension and cardiac arrhythmias -
E Wooltorton - Canadian Medical Association Journal, 2002 - Can Med Assoc
... 8 Sibutramine may also improve other cardiovascular risk factors including
hyperlipidemia and glycemic control in patients with type 2 diabetes. 10 , 11. ...

Absence of cardiac valve dysfunction in obese patients treated with sibutramine -
DS Bach - Obesity Research, 1999 - NAASO
... DE Arterburn, PK Crane, and DL Veenstra The Efficacy and Safety of Sibutramine for
Weight Loss: A Systematic Review Archives of Internal Medicine, May 10, 2004 ...

Prevalence of obesity and weight change during treatment in patients with bipolar I disorder -
A Fagiolini, E Frank, PR Houck, AG Mallinger, HA … - J Clin Psychiatry, 2002 - Mass Med Soc
... Patients who continued sibutramine treatment for 6 more months ... loss requires behavioral
changes, which may occur more ... weight-loss programs than via self-help. ...

Behavior Therapy and Sibutramine for the Treatment of Adolescent Obesity A Randomized Controlled … -
RI Berkowitz, TA Wadden, AM Tershakovec, JL … - JAMA, 2003 - Am Med Assoc
... for those participants who started taking sibutramine at month 6. The smaller weight
loss in the former group when switched to sibutramine may have been ...

Modern Medical Management of Obesity The Role of Pharmaceutical Intervention -
LJ ARONNE - Journal of the American Dietetic Association, 1998 - Elsevier
... With sibutramine, there is evidence that some of the comorbidities associated with
obesity ... comply with a low-fat weight loss diet, orlistat may help to improve ...

Paradoxical Effect of Sibutramine on Autonomic Cardiovascular Regulation -
AL Birkenfeld, C Schroeder, M Boschmann, J Tank, G … - Circulation, 2002 - Am Heart Assoc
... 12. Because sibutramine may have a central inhibitory effect mediated by 2 -adrenergic
receptors, the concomitant use of drugs that act on central 2 -adrenergic ...

Source: Google Scholar

Sibutramine may help some kids with obesity

Last Updated: 2007-12-20 17:00:17 -0400 (Reuters Health)

NEW YORK (Reuters Health) - The appetite-suppressing drug sibutramine (Meridia, Reductil) appears to promote weight loss in children with obesity that is not lifestyle related, according to findings published in the Journal of Clinical Endocrinology and Metabolism.

Previous reports have shown that simple counseling and other behavioral interventions are not particularly useful in promoting weight loss among children with hormone-related obesity or other types that are not tied to their lifestyle, Dr. Claude Marcus and colleagues from Karolinska University Hospital, Stockholm, Sweden, note.

They conducted a two-phase study of sibutramine treatment in such children. In the first phase, the children and the researchers were initially unaware who received sibutramine and who received inactive "placebo". In the second "open-label" phase, all of the subjects received (and were aware they received) sibutramine.

A total of 45 patients completed the first phase, and 42 were included in the final study. Of the 45 patients, 24 received placebo initially and thereafter sibutramine and 21 received sibutramine initially.

Weight loss occurred when the subjects were given sibutramine and not when they received placebo, the report indicates.

In the open-label phase, the reduction in weight continued, and the pattern of weight loss was similar in children who had received the placebo and those who were treated with sibutramine, Marcus and colleagues report.

The authors note that the treatment was well tolerated. "However," they advise, "because no long-term sibutramine studies are available in children...caution is warranted."

SOURCE: Journal of Clinical Endocrinology and Metabolism, November 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 

 

 

 

 
 
 
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