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Recent News and Articles on the Keywords: blood pressure + restore normal + kidney  Related to the article below (Last Update: 5/13/2008)

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Source: Google News

ABNORMAL KIDNEY FUNCTION AS A CAUSE AND A CONSEQUENCE OF OBESITY HYPERTENSION -
JE Hall, MW Brands, JR Henegar, EW Shek - Clinical and Experimental Pharmacology and Physiology, 1998 - Blackwell Synergy
... decrease tubular reabsorption, large increases in pressure, especially when ... increased
BP would then serve to restore the renal medullary blood flow and ...

ABC of hypertension: The pathophysiology of hypertension -
G Beevers, GYH Lip, EO'Brien - BMJ: British Medical Journal, 2001 - pubmedcentral.nih.gov
... but does not seem to restore the impaired ... 30% of the variation in blood pressure
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The Kidney, Hypertension, and Obesity -
JE Hall - Hypertension, 2003 - Am Heart Assoc
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R Bellomo, D Di Giantomasso - Crit Care, 2001 - ccforum.com
... If the physician wishes to restore arterial pressure (>80 ... the aim of sustaining organ
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-

Chronic treatment with tin normalizes blood pressure in spontaneously hypertensive rats -
B Escalante, D Sacerdoti, MM Davidian, M Laniado- … - Hypertension, 1991 - Am Heart Assoc
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P Wiesel, L Mazzolai, J Nussberger, T Pedrazzini - Hypertension, 1997 - Am Heart Assoc
... measured both in the contralateral normal kidney and in ... of angiotensinogen synthesis
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Analysis of the effect of hemodialysis on peripheral and central arterial pressure waveforms. -
A Covic, DJA Goldsmith, L Panaghiu, M Covic, J … - Kidney International, 2000 - pt.wkhealth.com
... in whom HD was not able to restore hemodynamics to normal, returned to ... Covic A,
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Atherosclerotic Renovascular Disease and Progressive Renal Failure -
JM Rimmer, FJ Gennari - Annals of Internal Medicine, 1993 - annals.highwire.org
... cell proliferation in the normal and injured ... revascularization to preserve and restore
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The kidney and essential hypertension: a link to osteoporosis? -
GA MacGregor, FP Cappuccio - J Hypertens, 1993 - ncbi.nlm.nih.gov
... responsible for the rise in blood pressure, but also cause an increase in central
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Aging and Endothelial Function in Normotensive Subjects and Patients With Essential Hypertension -
S Taddei, A Virdis, P Mattei, L Ghiadoni, A … - Circulation, 1995 - Am Heart Assoc
... receptor antagonists, diuretics) can restore normal endothelium-dependent ... G. Age-
and pressure-dependent changes ... A quantitative analysis of blood-brain barrier ...

Source: Google Scholar

Normal BP pattern restored in kidney patients

Last Updated: 2007-12-20 11:19:15 -0400 (Reuters Health)

NEW YORK (Reuters Health) - In "nondipper" patients with chronic kidney disease, individuals who don't experience the normal decline in blood pressure at night, changing the dose of one antihypertensive drug between morning and evening can restore the normal circadian rhythm, the results of a pilot study suggest.

Failure of blood pressure to drop by at least 10 percent at night is associated with an increased risk of developing cardiovascular and kidney complications, researchers in Italy note in the American Journal of Kidney Diseases. Nondipping status is highly prevalent in patients with chronic kidney disease, they add.

Dr. Roberto Minutolo and associates evaluated a "chronotherapeutic approach" among patients treated at the Nephrology Unit of the Second University of Naples. Included were 32 patients with chronic kidney disease, with a night-to-day ratio of average ambulatory blood pressure of more than 0.9, and normal blood pressure during the daytime.

The patients, who were taking an average of 2.4 antihypertensive medications each, were instructed to start taking one extra dose in the evening of any class of drugs, except diuretics.

After 8 weeks, the night-to-day ratio had decreased in 30 patients, and 28 patients achieved a normal dipping pattern of less than 0.9.

The average level of urinary protein excretion decreased significantly after the drug shift, from 271 milligrams per day to 182 milligrams per day, in correlation with the change in night-to-day blood pressure ratio.

The investigators observed no changes in body weight or two measures of kidney function -- the estimated glomerular filtration rate and daily urinary sodium excretion.

"The next logical question is whether lowering nocturnal blood pressure can retard the progression of chronic kidney disease and prevent cardiovascular complications," Dr. Mahboob Rahman, at Case Western Reserve University in Cleveland, and Dr. Lawrence J. Appel, at Johns Hopkins University in Baltimore, write in an accompanying editorial.

"The time is now ripe for a clinical outcomes trial of therapy that lowers nocturnal blood pressure," they add.

SOURCE: American Journal of Kidney Diseases, December 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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