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Recent News and Articles on the Keywords: lung cancer + cancer diagnosis + diagnosis  Related to the article below (Last Update: 5/5/2008)

Biomoda Appoints Three Business Leaders to Board of Directors
FOXBusiness -
"With their involvement, Biomoda is in an ideal position to influence the future of technology for early diagnosis and treatment of lung cancer throughout ...OTC:BMOD
Awareness may reduce minority cancer rates
Howard University The District Chronicles (subscription), DC -
A cancer diagnosis can be a devastating blow for patients and their loved ones. I should know: I am a 10-year survivor of prostate cancer. ...
Major League Baseball Hall of Famer Don Sutton Helps Kidney Cancer ...
FOXBusiness -
... other kidney cancer patients and their loved ones to understand that today, more than ever, many people can stay in the game even with this diagnosis," ...ONXX - OTC:CMTX
New cancer nurse is there to care
ChronicleLive, UK -
Joanne and Jane will be present at every diagnosis of lung cancer or mesothelioma in North Durham hospitals. They will be the key contacts for patients and ...
Rain doesn?t wash away walkers? dedication to Brockton cancer walk
Wicked Local Brockton, MA -
... who was only 23 when she lost her mother, Ann Marie Redd, to a case of lung cancer that killed the 51-year-old within a month of her diagnosis. ...
Cancer survivors give back
MetroWest Daily News, MA -
Since 1950, the American Cancer Society began conducting studies, the first of which was to study the connection between smoking and lung cancer. ...

BBC News
Inside medicine: Lung cancer nurse
BBC News, UK - May 2, 2008
... attached to lung cancer and that they brought it on themselves through smoking so shouldn't ask for help. This must change, as early diagnosis is vital. ...
Health & Fitness Calendar: Body Conditioning
commercialappeal.com (subscription), TN -
Support group and education for women who have had a diagnosis of cancer. Call 202-7639. Circle of Survivors: Meeting, 5:30 pm Thursday at Flying Colors ...
Depression After Diagnosis of Advanced Non-Small Cell Lung Cancer ...
Psychosomatics (subscription) - Apr 30, 2008
OBJECTIVE: This pilot study investigates the association of depression and survival in advanced non-small cell lung cancer (NSCLC) patients. ...

Business Wire (press release)
Compugen Announces Discovery of Blood Based Biomarker for ...
Business Wire (press release), CA - Apr 29, 2008
... for the diagnosis of small cell lung cancer and as a component in a biomarker combination for the diagnosis of non-small cell lung cancer patients. ...CGEN
Source: Google News

… of p16 (INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis -
SA Belinsky, KJ Nikula, WA Palmisano, R Michels, G … - Proc Natl Acad Sci US A, 1998 - pubmedcentral.nih.gov
... National Academy of Sciences. Medical Sciences. Aberrant methylation of p16 INK4a
is an early event in lung cancer and a potential biomarker for early diagnosis ...

Detection of oncogene mutations in sputum precedes diagnosis of lung cancer -
L Mao - Cancer Research, 1994 - AACR
... Association for Cancer Research. ARTICLES. Detection of oncogene mutations
in sputum precedes diagnosis of lung cancer. L Mao, RH Hruban ...

Multiclass cancer diagnosis using tumor gene expression signatures -
S Ramaswamy, P Tamayo, R Rifkin, S Mukherjee, CH … - Proceedings of the National Academy of Sciences, 2001 - National Acad Sciences
... BR, breast adenocarcinoma; PR, prostate adenocarcinoma; LU, lung adenocarcinoma;
CR ... of this multiclass SVM-based classifier in cancer diagnosis was first ...

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis -
N Yanaihara, N Caplen, E Bowman, M Seike, K … - Cancer Cell, 2006 - Elsevier
... Opens New Window). Article. Unique microRNA molecular profiles in lung cancer
diagnosis and prognosis. Nozomu Yanaihara 1 , Natasha ...

Detection of K-ras Oncogene Mutations in Bronchoalveolar Lavage Fluid for Lung Cancer Diagnosis -
NE Mills, CL Fishman, J Scholes, SE Anderson, WN … - jnci, 1995 - jnci.oxfordjournals.org
... 14, 1056-1060, July 19, 1995 ? 1995 Oxford University Press Detection of K-ras Oncogene
Mutations in Bronchoalveolar Lavage Fluid for Lung Cancer Diagnosis. ...

Endoscopic Ultrasound With Fine-Needle Aspiration in the Diagnosis and Staging of Lung Cancer -
GA Silvestri, BJ Hoffman, MS Bhutani, RH Hawes, L … - The Annals of Thoracic Surgery, 1996 - Soc Thorac Surgeons
... Endoscopic Ultrasound With Fine-Needle Aspiration in the Diagnosis and Staging of
Lung Cancer. ... The diagnosis of lung cancer was established in 7 patients. ...

… Alterations in Plasma DNA of Non-Small Cell Lung Cancer Patients: A Prospect for Early Diagnosis -
G Sozzi, K Musso, C Ratcliffe, P Goldstraw, MA … - Clinical Cancer Research, 1999 - AACR
... Advances in Brief. Detection of Microsatellite Alterations in Plasma DNA of
Non-Small Cell Lung Cancer Patients: A Prospect for Early Diagnosis 1. ...

Analysis of Circulating Tumor DNA in Plasma at Diagnosis and during Follow-Up of Lung Cancer -
G Sozzi, D Conte, L Mariani, S Lo Vullo, L Roz, C … - Cancer Research, 2001 - AACR
... such as low-dose spiral computed tomography and positron emission tomography, should
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The molecular basis and potential role of survivin in cancer diagnosis and therapy -
DC Altieri - Trends in Molecular Medicine, 2001 - Elsevier
... 3. Molecular diagnosis of cancer by survivin detection ... the immune response to survivin
in cancer patients might ... patients with cancers of colon and lung, but not ...

DNA methylation analysis: a powerful new tool for lung cancer diagnosis -
JA Tsou, JA Hagen, CL Carpenter, IA Laird-Offringa - Oncogene, 2002 - nature.com
... Review. DNA methylation analysis: a powerful new tool for lung cancer diagnosis. ...
An early diagnosis of lung cancer is not easily made (reviewed by Black, 1999). ...

Source: Google Scholar

Biomarkers in blood aid lung cancer diagnosis

Last Updated: 2007-12-18 16:12:00 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Four proteins in the blood appear to be useful in helping to establish a diagnosis of lung cancer, North Carolina-based researchers report in the Journal of Clinical Oncology.

Lead investigator Dr. Edward F. Patz, Jr., told Reuters Health that his group believes that a combination of these biomarkers may be helpful in determining the probability of lung cancer in patients whose diagnosis can't be determinate by imaging studies.

Patz and colleagues at Duke University Medical Center, Durham note that currently there is no blood test for lung cancer, but blood biomarkers could be "enormously valuable."

In an effort to develop appropriate biomarkers, the researchers investigated six serum proteins and found that four, collectively, were promising -- carcinoembryonic antigen, retinol binding protein, alpha-1-antitrypsin, and squamous cell carcinoma antigen.

The team examined blood samples from 50 patients with newly diagnosed lung cancer and 50 "controls" without lung cancer. A validation set of 49 patients and 48 controls were also investigated.

Measurement of the four protein markers correctly classified all of the patients and controls at least 75 percent of the time.

The researchers used a "classification tree" to help them determine the probability of cancer based on protein levels. "People whose samples landed in one of three bins at the bottom of the tree had a 90-percent chance of having cancer," said Patz in a statement. "Other bins indicated risks as low as 10 percent."

Patz concluded that "additional trials will help us refine the role of this panel in diagnosing patients with lung cancer."

SOURCE: Journal of Clinical Oncology, December 10, 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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