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dBTechno
Posted by: Rob Hof on May 12
BusinessWeek -
What you notice immediately when searching on something, whether it?s in the form of a question or the usual keyword combinations, is that Powerset?s engine ...
Powerset Unveils Test Version of Google-killer ABC News
Powerset Launches Showcase For User Search Experience Washington Post
Powerset shows semantic search solution ZDNet Blogs
TechNewsWorld - RedOrbit
all 141 news articles »  GOOG - MSFT

bit-tech.net
Image-based search with TinEye
bit-tech.net, UK - 33 minutes ago
Wouldn't it be handy if you could just upload the closest equivalent image you have and let the power of the web do its magic thing? ...
Relevancy is What Matters in SEM
Promotion World (press release), CA - May 12, 2008
Keywords are just the tip of the search query iceberg: Advertise the keyword ?bicycle? on broad match and you could very well serve for searches on the ...
SEO and Meta Tags
Promotion World (press release), CA -
So, with present algorithms which are really smart and intelligent include only those relevant keywords you want to target and make sure that these are ...
Making the most of being a certified disadvantaged firm
Los Angeles Times, CA - May 12, 2008
Answer: There are professionals who do nothing but "optimize" websites for prominent search engine placement. If you can't afford one, here are some tips ...
SherpaBlog: 5 Ways to Improve Blog Results Today: How to Engage ...
MarketingSherpa.com (subscription), RI - May 11, 2008
While it?s fine to see how many visitors you get, the most useful report is actually the keyword analysis report. There, you?ll find a list of the terms ...
Good Old-Fashioned Link Building
ClickZ News, NY - May 11, 2008
You search for potential linking partners, approach them and ask for a link (and often you provide one in return). I refer to this approach as a "direct" ...

R744.com
? R744.com has evolved...
R744.com, Belgium - 33 minutes ago
Members section: After your FREE registration as an R744.com Member, you have full access to all additional features offered on the website, ...
Search Engine News, An In-Depth Look At Google's Tools & The ...
Search Engine Land, CT - May 9, 2008
This week, there was an update of the Keyword Tool. "You may have noticed that we made a change the traffic estimates data in the Keyword Tool. ...GOOG
SmartFinds Internet Marketing Improves Web Site Results for Top ...
PR Web (press release), WA -
You can learn more about SmartFinds at SmartfindsMarketing.com. Contact: Doug Menzer, PO Box 370, Bloomfield Hills, MI 48303, (866) 501-5758.PINK:IMIZ
Source: Google News

[CITATION] Inc
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Statistical analysis of cointegration vectors
S Johansen - Journal of Economic Dynamics and Control, 1988 - ideas.repec.org
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Measuring the efficiency of decision making units -
A Charnes, WW Cooper, E Rhodes - European Journal of Operational Research, 1978 - ideas.repec.org
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The Brazilian Cerrado Vegetation and Threats to its Biodiversity -
JA RATTER, JF RIBEIRO, S BRIDGEWATER - Annals of Botany, 1997 - Annals Botany Co
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The relationship between return and market value of common stocks
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In search of a useful theory of innovation -
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Pulmonary complications of bone marrow transplantation -
AO Soubani, KB Miller, PM Hassoun - Chest - Am Coll Chest Phys
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Staggered Prices in a Utility-Maximizing Framework
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Management Ownership and Market Valuation: An Empirical Analysis
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Source: Google Scholar

Research Says Diabetics Most At Risk From Neglected Post Meal Sugar Peak

 
Christmas time is full of food when most of us simply have to worry about our expanding waist lines but new research led by the University of Warwick's Medical School says that people with diabetes need to pay attention to the dangers of a neglected post meal peak in blood glucose. Indeed the research shows that this post meal peak can do even more damage than a more sustained rise in blood sugar.

Until recently, the main focus of therapy for people with diabetes has been on lowering blood sugar or glycated haemoglobin (HbA1c) levels, with a strong emphasis on fasting plasma glucose. People with diabetes are now extremely proficient at maintaining the best overall blood glucose levels. However this new study shows that that is insufficient in itself to obtain optimal glycaemic control.

The research report entitled "Guideline for management of Postmeal Glucose" was carried out for The International Diabetes Federation by an international panel of diabetes specialists chaired by Professor Antonio Ceriello of Warwick Medical School at the University of Warwick.
The Warwick Medical School researchers looked at a range of studies that examined in particular the two hour post meal peak in blood sugars and found a substantial body of evidence that reducing postmeal plasma glucose is as important, perhaps even more important for achieving overall optimum HbA1c levels.

Postmeal plasma glucose levels seldom rise above 7.8 mmol/l (minimoles per litre) in people with normal glucose tolerance and typically return to normal levels two to three hours after food ingestion. Therefore it would be best to ensure that the two-hour postmeal plasma glucose levels in people with diabetes should also not exceed 7.8 mmol/l as long as hypoglycaemia is avoided.

However the Warwick Medical School researchers found a number of studies in which this was not the case. In one cross-sectional study of 443 individuals with type 2 diabetes, 71% of those studied had a mean two hour post meal plasma glucose of greater then 14 mmol/l. Another study looking at daily plasma glucose profiles from 3,284 people with non-insulin-treated type 2 diabetes showed that post meal plasma glucose values of greater than 8.9 mmol (160 mg/dl) were recorded at least once in 84% of those studied.

The researchers also found a number of studies that suggested that the intensity of these post meal blood sugar peaks (and the obvious increased variability they bring to people's glucose levels) can sometimes do even more damage than sustained high blood sugar levels.

Numerous studies support the hypothesis of a causal relationship between hyperglycaemia and oxidative stress leading to vasoconstriction (a narrowing of the blood vessels) and thus high blood pressure. Acute glycaemic variability appear to play particular important roles in this mechanism. One study examined human umbilical vein endothelial cells that were subjected in cell culture to steady state and alternating glucose concentrations which found that variability in glucose levels may be more damaging than a constant high concentration of glucose.

Other studies examined by the research team included: a study that showed the post meal peak increased the risk of atherosclerosis is (chronic inflammation in the walls of arteries), a study from Japan that demonstrated that postmeal hyperglycaemia is a better predictor of diabetic retinopathy (non-inflammatory damage to the retina of the eye) than HbA1c, a study linking it to increased damage to cells that line the inner surface of all blood vessels, research linking it to diabetes related kidney disease, pancreatic cancer, and much more.

The research noted a number of effective dietary and pharmaceutical methods were available to effectively target the problem of postmeal plasma glucose and said that self-monitoring of blood glucose (SMBG) was the best and most practical method for monitoring postmeal glycaemia. SMBG allows people with diabetes to obtain and use information about "real-time" plasma glucose levels. This facilitates timely intervention to achieve and maintain near-normal glycaemia and provides feedback to people with diabetes. Most diabetes organizations and other medical associations advocate use of SMBG in people with diabetes.

The researchers also concluded that a two-hour timeframe for measurement of plasma glucose concentrations was the safest for people treated with insulin. This was because testing any earlier than that could cause people to respond inappropriately to, for instance, elevated one-hour plasma glucose levels with additional insulin without waiting for their initial intake of insulin to take full effect. This can lead to a problem is often referred to as "insulin stacking," and can lead to severe hypoglycaemia.

The research also pointed to the benefits of the emerging technology of Continuous glucose monitoring to help self monitoring people with diabetes keep track of this post meal peak.

CGM employs a sensor to measure glucose every 1 to 10 minutes and transmits this reading to a data storage device. Results can be either downloaded to a doctor, or displayed in "real time" in the monitor.

WARWICK UNIVERSITY
Coventry
http://www.warwick.ac.uk
 
 
 
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