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Recent News and Articles on the Keywords: genomic medicine + medical college + medicine  Related to the article below (Last Update: 5/5/2008)

Combined Physical And Genetic Map Finds Cancer's 'Ignition Key'
Science Daily (press release) -
Co-authors also include R. Alan Harris and Steven Scherer of Baylor College of Medicine's Department of Molecular and Human Genetics and Human Genome ...
Research unit established Gulf Medical College
ArabianBusiness.com (press release), United Arab Emirates - May 4, 2008
TS Sridhar Professor of Molecular Medicine spoke about Establishing Research Programs, and presented a paper on Genomic Cancer Research. ...
Compugen, International Cancer Genome Consortium, American College ...
Pharmacogenomics Reporter (subscription), NY - Apr 30, 2008
Biomax Informatics said last week that it has been selected as a consortium partner in Austria?s OncoTyrol project Center for Personalized Cancer Medicine. ...TWTI
Baylor College of Medicine to Use Applied Biosystems Genetic ...
Business Wire (press release), CA - Apr 24, 2008
?The successful completion of this project should enable broader applications of genomic analysis and open the door for a host of personalized medicine, ...ABI
House bars use of genetic data in jobs, insurance
Baltimore Sun, United States - May 2, 2008
"It really has been this fear of discrimination that has been the largest barrier, we think, to widespread acceptance of genomic medicine," said Dr. Alan E. ...
CCC to host Coriell gene sessions
Gloucester County Times - NJ.com, NJ - Apr 27, 2008
The study aims to educate medical professionals about personalized medicine and guide the integration of genomic information into clinical decision-making. ...
Coriell offers free genetic screening project
Cherry Hill Courier Post, NJ - Apr 29, 2008
Coriell launched its genome project to educate medical professionals and the public about personalized medicine and guide the integration of genomic ...

Business Gazette
Genomics pioneer
Business Gazette, MD - Apr 17, 2008
??We will be able to do bigger and better things together,? said Alan R. Shuldiner, director of the Program in Genetics and Genomic Medicine. ...
Human genetics: Dr Watson's base pairs
Nature.com (subscription), UK - Apr 18, 2008
At the information-carrying core of this beautiful structure, with its far-reaching implications for biology and medicine, are the base pairs that Watson ...
Premier's Innovation Awards Celebrate Excellence
Canada NewsWire (press release), Canada - Apr 30, 2008
This technology is used in Sony Playstation 3, QBase's business intelligence software, Dartmouth Medical College's cancer detection software, and Masstech's ...
Source: Google News

Genome sequence of the Brown Norway rat yields insights into mammalian evolution -
RA Gibbs, GM Weinstock, ML Metzker, DM Muzny, EJ … - Nature, 2004 - adsabs.harvard.edu
... California 95064, USA;), IM(UCSC Genome Bioinformatics Group ... USA;), IN(Center for
Comparative Genomics and Bioinformatics ... of Wales College of Medicine, Heath Park ...

[BOOK] The Genetic Basis of Human Cancer
B Vogelstein, KW Kinzler - 2002 - books.google.com
... MD National Center for Human Genome Research Bethesda ... Molecular Genetics Institute
of Medical Genetics University of Wales College of Medicine Cardiff, Wales ...

Transmission of Hepatitis C Virus from Mothers to Infants -
H Ohto, S Terazawa, N Sasaki, N Sasaki, K Hino, C … - New England Journal of Medicine, 1994 - content.nejm.org
... seven infected infants we studied, the genomic sequence of ... the Second Department
of Internal Medicine, National Defense Medical College, Saitama (KH ...

[BOOK] Genetic Instabilities and Neurological Diseases
RD Wells, T Ashizawa, ST Warren, M Sarmiento - 2006 - books.google.com
... 41) Program of Genetics and Genomic Biology, The ... Department of Molecular and Medical
Genetics, University ... Biology, Baylor College of Medicine, Houston, Texas ...

… To Differentiate the Subspecies of the Mycobacterium tuberculosis Complex on the Basis of Genomic … -
RC Huard, LC de Oliveira Lazzarini, W Butler, D … - Journal of Clinical Microbiology, 2003 - Am Soc Microbiol
... tuberculosis Complex on the Basis of Genomic Deletions. ... Infectious Diseases, Department
of Medicine, Joan and Sanford I. Weill Medical College, 1 Graduate ...

Plasma Ghrelin Levels in Lean and Obese Humans and the Effect of Glucose on Ghrelin Secretion -
T Shiiya, M Nakazato, M Mizuta, Y Date, MS Mondal, … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc
... Ph.D., Third Department of Internal Medicine, Miyazaki Medical College, Kiyotake,
Miyazaki ... Recent efforts in genomics research have identified a large ...

[PDF] Structural genomics: beyond the human genome project -
SK Burley, SC Almo, JB Bonanno, M Capel, MR Chance … - Nat. Genet, 1999 - salilab.org
... 151 Structural genomics: beyond the Human Genome Project ... 3 Albert Einstein College
of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA. ...
-

[BOOK] Candida and Candidiasis -
RA Calderone - 2002 - books.google.com
... Sullivan Department of Oral Medicine and Pathology, Micro ... near completion of the
genome sequence of ... properties, cell biology, immunity, genomics, diseases and ...

Microarray Analysis of Gene Expression in the Kidneys of New-and Post-Onset Diabetic NOD Mice -
KHS Wilson, SE Eckenrode, QZ Li, QG Ruan, P Yang, … - Diabetes, 2003 - Am Diabetes Assoc
... She, Center for Biotechnology and Genomic Medicine, Medical College of Georgia ... A
Frontier for Personalized Medicine J. Am ... Genomics Home page KE Knoll, JL Pietrusz ...

[BOOK] Psychiatric Genetics and Genomics -
P McGuffin, MJ Owen, II Gottesman - 2002 - books.google.com
... 17 The future and post-genomic psychiatry 449 ... Appendix 2: Psychiatric genetics and
genomics-an update 469 ... University of Wales College of Medicine, Cardiff UK ...

Source: Google Scholar

MCG selected as RNA laboratory for worldwide diabetes study

 

The Medical College of Georgia Center for Biotechnology and Genomic Medicine has been selected to isolate RNA and DNA from the blood of thousands of children involved in a worldwide study of the causes of type 1 diabetes.

MCG also is enrolling children in the mammoth study that will eventually follow 8,000 at-risk babies from four states and three countries for 15 years, collecting blood every three months as they go.

The TEDDY – The Environmental Determinants of Diabetes in the Young – study is keeping tabs on many aspects of the children’s lives – from emergency room visits to over-the-counter medicines – in an effort to identify environmental triggers for diabetes in children with known high-risk genes.

“Once you know the risk factors, you can modulate the risk factors to prevent diabetes,” says Dr. Jin-Xiong She, center director and Georgia Research Alliance Eminent Scholar in Genomic Medicine.

Dr. She was among the scientists who conceived the idea of TEDDY and successfully applied for National Institutes of Health funding to pursue it in 2003.

He recently was named principal investigator on the additional five-year, $5 million contract to isolate RNA and DNA from the regularly collected blood.

About 20,000 samples already are awaiting the process. The MCG Center developed a robotic automation that processes 96 samples in about two hours – compared to the standard of a few samples in about six hours – to handle the huge and growing volume.

Gene expression over time is a new area of research, says Dr. She. The newly established infrastructure enables MCG to isolate nucleic acids for similar large-scale studies.

Isolated nucleic acids will be stored at the National Institute of Diabetes and Digestive and Kidney Diseases Repository. TEDDY scientists will eventually analyze the impact of environmental triggers on the body’s basic building blocks with an eye toward identifying biomarkers that give an early heads up that the body is headed toward diabetes.

“These two different types of genetic material contain different information,” Dr. She explains. “The basic information of DNA does not change. What changes in DNA is how it may or may not allow expression of genes. RNA changes all the time.”

“Think about when you get the flu and your body starts to increase the number of immune cells to fight it,” says Dr. Richard A. McIndoe, associate center director and co-principal investigator. “That requires an expansion of your cells, which requires an expansion of proteins, which requires an expansion of RNA. Infection is an environmental trigger. Your RNA changed because you had an infection.”

“When you are getting diabetes, your RNA expression also changes,” says Dr. She. Changes may or may not be permanent, but the goal is to connect the pieces and see which changes amount to type 1 diabetes, he says.

MCG’s TEDDY Clinical Center is screening newborns in nine hospitals, including MCG Medical Center, University Hospital, Trinity Hospital of Augusta; Northside, Piedmont and Kennestone Hospitals in Atlanta; and three hospitals in Gainesville, Fla. Additional centers include Barbara Davis Center at the University of Colorado; Pacific Northwest Research Institute in Seattle; the University of Turku in Finland; Lund University in Sweden; and the Diabetes Research Institute in Munich, Germany. The University of South Florida in Tampa serves as the TEDDY data coordinating center and MCG’s new contract with the NIDDK for nucleic acid isolation is through that university.

To date, MCG’s center has enrolled about 500 children. An additional 800 to 1,000 enrollees in the next two-and-one-half years are planned.

 
 
 
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