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Recent News and Articles on the Keywords: johns hopkins + news release + 2007  Related to the article below (Last Update: 5/13/2008)

BALTIMORE COUNTY CIRCUIT COURT: Man pleads guilty in beating death ...
Dundalk Eagle, MD -
11, 2007, was taken to Johns Hopkins Bayview Medical Center, doctors found head injuries and had him flown to a children?s hospital in Washington, ...
To Avoid Dementia, Watch Your Weight
WebMD - May 8, 2008
Researchers with Johns Hopkins Bloomberg School of Public Health in Baltimore have found that obese people have an 80% increased risk for Alzheimer's ...
Plan To Send A Probe To The Sun
Science Daily (press release) - May 2, 2008
ScienceDaily (May 2, 2008) ? The Johns Hopkins University Applied Physics Laboratory is sending a spacecraft closer to the sun than any probe has ever gone ...
TorreyPines Therapeutics Licenses Intellectual Property from Johns ...
CNNMoney.com (press release) - May 1, 2008
This press release contains forward-looking statements or predictions. Such forward-looking statements include, but are not limited to, statements regarding ...TPTX
Lost and found
Science News - May 9, 2008
... adds Judith Bass of Johns Hopkins University in Baltimore . In a 2007 study, her team adapted a form of group therapy for use in Uganda . ...
Corporate Office Properties Trust Reports First Quarter 2008 Results
WELT ONLINE, Germany - May 6, 2008
11 167007 1.0% 3290 0.9% 0.9 BAE Systems PLC (6) 7 212339 1.3% 3099 0.9% 3.7 The Johns Hopkins Institutions (6) 4 124749 0.7% 2911 0.8% 8.3 Merck & Co., ...OFC
Orexigen(R) Therapeutics Announces First Quarter 2008 Financial ...
Business Wire (press release), CA - May 8, 2008
... immediate release (IR) for the Company?s Phase II trials was selected on the basis of a PET imaging study conducted at Johns Hopkins University. ...OREX
Neuralstem Responds to Incorrect StemCells, Inc. Release on Patents
FOXBusiness - Apr 16, 2008
... Johns Hopkins University researchers, and also reversed paralysis in rats with Ischemic Spastic Paraplegia, as reported in NEUROSCIENCE on June 29, 2007 ...STEM
Murders This Year: 65
Baltimore City Paper, MD - May 6, 2008
Henderson was hit repeatedly and died at Johns Hopkins Hospital at 2:31 am His friend was taken to a hospital in stable condition and is expected to live. ...
Regeneron and Bayer HealthCare Announce Encouraging 32-Week Follow ...
InfoBolsa, Spain - Apr 30, 2008
Nguyen does not necessarily imply endorsement by the Johns Hopkins University, the Johns Hopkins Hospital, or the Johns Hopkins Medical Institutions.REGN
Source: Google News

A Positive Theory of Monetary Policy in a Natural Rate Model -
RJ Barro, DB Gordon - The Journal of Political Economy, 1983 - UChicago Press
... Press Release. An-arrgh-chy! >> Read full press release. >> Go to press release
archive. In the News. ... Johns Hopkins University Press, 1986. ...

Enzyme-independent formation of nitric oxide in biological tissues -
JL Zweier, P Wang, A Samouilov, P Kuppusamy - Nature Medicine, 1995 - nature.com
... The Johns Hopkins Medical Institutions, Johns Hopkins Bayview Medical Center, 5501
Hopkins Bayview Circle ... Moncada, S. Nitric oxide release accounts for ...

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in … -
K Conant, A Garzino-Demo, A Nath, JC McArthur, W … - Proceedings of the National Academy of Sciences, 1998 - National Acad Sciences
... and Department of Epidemiology, Johns Hopkins University School ... 1 (MCP-1). Astrocytic
release of -chemokines ... by other articles in HighWire Press-hosted journals ...

Rules Rather than Discretion: The Inconsistency of Optimal Plans -
FE Kydland, EC Prescott - The Journal of Political Economy, 1977 - UChicago Press
... Press Release. An-arrgh-chy! >> Read full press release. >> Go to press release
archive. In the News. ... Johns Hopkins University Press, 1986. ...

Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory … -
J Nicholas, VR Ruvolo, WH Burns, G Sandford, X Wan … - Nature Medicine, 1997 - nature.com
... 2 Department of Pharmacology and Molecular Sciences, Johns Hopkins University School
of Medicine, Baltimore ... Oncogene 10, 2007-2016 (1995). ... (in the press). ...

Spurious Volatility in Historical Unemployment Data -
C Romer - The Journal of Political Economy, 1986 - UChicago Press
... Press Release. An-arrgh-chy! >> Read full press release. >> Go to press release
archive. In the News. ... Johns Hopkins University Press, 1986. ...

Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15 -
A Okumura, G Lu, I Pitha-Rowe, PM Pitha - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences
... Communicated by Diane E. Griffin, Johns Hopkins Bloomberg School of ... by other articles
in HighWire Press-hosted journals: ... Factor 3 and to the Release of Beta ...

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24 -
J Gudmundsson, P Sulem, A Manolescu, LT … - Nat Genet, 2007 - nature.com
... Published online: 1 April 2007; | doi:10.1038/ng1999 ... Institutional Review Board of
Johns Hopkins University approved ... were calculated from HapMap release 16a by ...

Genome scan of human systemic lupus erythematosus: Evidence for linkage on chromosome 1q in African- … -
KL Moser, BR Neas, JE Salmon, H Yu, C Gray-McGuire … - Proceedings of the National Academy of Sciences, 1998 - National Acad Sciences
... Provost, Department of Dermatology, Johns Hopkins Hospital, Baltimore ... other articles
in HighWire Press-hosted journals: ... Preliminary Analysis and Data Release Ann ...

Biochemical characterization of Wnt-Frizzled interactions using a soluble, biologically active … -
JC Hsieh, A Rattner, PM Smallwood, J Nathans - Proceedings of the National Academy of Sciences, 1999 - National Acad Sciences
... 725 North Wolfe Street, Johns Hopkins University School ... by other articles in HighWire
Press-hosted journals ... dependent Synaptic Wnt Release Regulates Hippocampal ...

Source: Google Scholar

Cell 'Addiction' to Growth Factors May Help Spur Cancers

Study in mice shows blocking this dependence could stop disease before it starts

(SOURCE: Johns Hopkins Medicine, news release, Dec. 10, 2007)

THURSDAY, Dec. 13 (HealthDay News) -- "Addiction" to certain growth factors contributes to the development of cancers caused by epigenetic changes, such as the inappropriate activation of a normally silent gene, scientists say.

The team of Johns Hopkins University researchers believe that blocking this addiction might help prevent cancer growth.

They compared mouse cells with only one copy of the IGF-II (insulin-like growth factor two) gene activated to mouse cells with both copies of IGF-II activated. Normally, only one copy of the IGF-II gene is activated.

In humans, activation of both IGF-II genes has been linked with a fivefold increased risk of intestinal tumors.

Mouse cells with one activated copy of the IGF-II gene responded to normal doses of IGF-II growth factor and recovered within 90 minutes. The cells with both copies of the IGF-II gene responded to the smallest doses of growth factor and stayed that way for more than 120 minutes.

Working with mice bred to develop colon cancer, the researchers then administered a drug that blocks the cell's ability to respond to IGF-II growth factor. The mice developed 70 percent fewer precancerous lesions than untreated mice.

"Finding the molecular mechanism behind cancer development allowed us to use a specific drug to actually take care of these risky cells before the animal developed cancer. It's making us think about cancer prevention in a whole new way," Dr. Andrew Feinberg, professor of medicine, oncology and molecular biology and genetics, and director of the Epigenetics Center at Hopkins, said in a prepared statement.

"If this is transferable to people, it could be really exciting," Feinberg said. "It means we might be able to do something about at-risk cells before cancer develops and treat these cells biochemically, and specifically, rather than using current drugs that are nonspecific and kill everything in their path."

The study was expected to be published online next week in the journal Proceedings of the National Academy of Sciences.

More information

The U.S. National Cancer Institute has more about cancer genetics.

 

 

 
 
 
 
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