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Recent News and Articles on the Keywords: male infertility + breakthrough + could  Related to the article below (Last Update: 5/13/2008)


Daily Sun
Assisted reproduction answer to infertility
Daily Sun, Nigeria - May 5, 2008
There are various causes of infertility. It could be male-factor problem or it could be female. It could also be genetic. If it is a male factor problem, ...

CNN
A mom's guide to birth control
CNN - Apr 22, 2008
One downside: It often causes breakthrough bleeding, so you'd have to be willing to put up with that. Parenting.com: When birth control masks infertility Q: ...
Source: Google News

… of Y-chromosomal microdeletions in the work-up of male infertility. Initiative for international … -
M Simoni, A Kamischke, E Nieschlag - Human Reproduction, 1998 - ESHRE
... Reijo et al., 1995), a major breakthrough in the ... of a very large set of primers could
be polymorphic ... the Y chromosome play a causal role in male infertility. ...

Phytochemicals and the breakthrough of traditional herbs in the management of sexual dysfunctions -
A Adimoelja - International Journal of Andrology, 2000 - Blackwell Synergy
... Tejada, 1992; Shirai, 1992), a breakthrough was heralded ... Experiments on male fertility
and sexual functions, Go to ... nondiabetic and 15 diabetic male patients with ...

[BOOK] Male Infertility--Men Talking -
MC Mason - 1993 - books.google.com
... potential was essentially unquestioned, impotence the only acknowledged cause of
male infertility (Spark, 1988). In the Old Testament men could take on ...

Rewards and risks in ICSI Intracytoplasmic sperm injection (ICSI): potential genetic concerns -
P Patrizio - Human Reproduction, 1995 - ESHRE
... then the incorporation of paternal (grandmother) DNA could be seen as ... it has become
the most significant breakthrough in the treatment of male infertility. ...

Male infertility and intracytoplasmic sperm injection (ICSI) -
AJ Campbell, DS Irvine - British Medical Bulletin, 2000 - British Council
... They concluded that male infertility could be treated by IVF-ET ... couples with problems
in the male partner 39 ... very limited until the breakthrough of effective ...

Male infertility: recent advances and a look towards the future. -
DJ Lamb, LI Lipshultz - Current Opinion in Urology, 2000 - co-urology.com
... to sperm entry, this scientific breakthrough will allow ... because genetic causes of
male infertility may be ... to the agricultural industry, could markedly change ...

Male Infertility -
RB Meacham, GF Joyce, M Wise, A Kparker, C … - The Journal of Urology, 2007 - Elsevier
... second global conference on infertility showed that ?the current treatment of male
infertility has become so dominated by the breakthrough technology of ICSI ...

… models and germ cell transplantation: two excellent tools for the analysis of genes regulating male -
J Wistuba, S Schlatt - Molecular Genetics and Metabolism, 2002 - Elsevier
... therapeutical applications to treat male sub/infertility [21 ... 3). The presence and
availability of male germ line ... This breakthrough is of great impact, follow up ...

Genetically engineered cytoplasmic male sterility -
CD Chase - Trends in Plant Science, 2006 - Elsevier
... mitochondrial gene regulation and male fertility in higher ... and H. Daniell, Cytoplasmic
male sterility engineered ... H. Daniell et al., Breakthrough in chloroplast ...

Endocrine Disrupters and Male Infertility
SC Sikka, RK Naz - … Disruptors: Effects on Male and Female Reproductive Systems, 1999 - books.google.com
... the most important recent breakthrough in the ... Sites An environmental agent could
disrupt endocrine ... Endocrine Disrupters and Male Infertility 229 3. Secrete ...

Source: Google Scholar

Experiment could be male infertility breakthrough

In a breakthrough that could help improve the treatment of male infertility, scientists have produced mice using sperm grown in the laboratory from embryonic stem cells.

They isolated stem cells from very early mouse embryos, sorted those that had begun to develop into early-stage sperm cells and coaxed them through various stages until they resembled sperm cells known as gametes.

After injecting the cells into mouse eggs, the embryos that formed were transplanted in female mice. Seven baby mice were born, six of which developed into adults.

"This is the first time it is shown that it is possible to make mature sperm from stem cells," said Professor Karim Nayernia who headed the team at the University of Gottingen in Germany.

"It is the scientific basic for understanding male infertility. Because before we treat any disease we should understand the disease on the molecular and genetic level," he added in an interview.

Stem cells are master cells in the body that can transform themselves into other cell types. Scientists believe they could act as a type of repair system to provide new treatments for illnesses ranging from diabetes to heart disease.

But their use is controversial because stem cells found in early embryos have the greatest therapeutic potential. Adult stem cells have a more limited range.

Professor John Burn, head of the Institute of Human Genetics at Newcastle University in England, described the research published in the journal Developmental Cell as a milestone.

"One could imagine in years to come the knowledge gained from this analysis of the pathway of development will lead us into ways of understanding why some men are infertile," he said.

About one in six couples worldwide experience some form of infertility. Roughly 40 percent of cases are linked to a problem in men. A low sperm count, no sperm at all or poor movement or shape are causes of male infertility.

Nayernia, now at Newcastle University, has been working on the research for three years. His team created 400 embryos but only a handful resulted in live mice because of technical and developmental problems.

"This is important work which builds on a number of discoveries showing that embryonic stem cells can generate sperm and eggs in the lab," said Harry Moore, a professor of reproductive biology at the University of Sheffield, in a statement.

 

Education program improves melanoma screening

Public education efforts to raise awareness of the risk factors for malignant melanoma, along with improved access to screening exams, can improve melanoma screening rates among men 50 years of age and older, new research suggests.

The findings, which will appear in the medical journal Cancer, are based on a study of more than 400 men living in 18 communities in Queensland, Australia.

Nine of the communities were assigned to a 3-year intervention that included community and physician education campaigns as well as the establishment of clinics dedicated to skin screening. The other nine communities received no intervention.

Two years after the start of the program, men were four-times more likely than before to report having a clinical whole-body skin examination in the preceding 12 months, and they were twice as likely to have performed whole-body skin self-examination.Men 50 years of age or older accounted for 20 percent of screening visits at the clinic but they yielded 48 percent of the melanomas diagnosed, report Dr. Monika Janda of the Queensland Cancer Fund in Spring Hill, Australia and colleagues."The intervention program successfully motivated men aged at least 50 years to attend screening for skin cancer, resulting in the highest yield of skin cancer within this subgroup of the population," the team concludes.

Meanwhile, in the same issue of Cancer, Dr. Alan C. Geller, from Boston University, and colleagues describe an initiative to improve early detection and prevention practices among siblings of melanoma patients.

Some 400 siblings were randomly assigned to "usual care" or to an intervention that included personalized telephone counseling, the use of computer-generated educational materials, and linkage to free screening programs. At 12-month follow-up, those who received the intervention were 76 percent more likely than usual-care siblings to examine all moles, including those found on the back. The rates of skin cancer examination, although not different between the groups, more than doubled during the course of the study. Similarly, two thirds of the subjects in each group reported routine use of sunscreen at follow-up. "Diagnosis of melanoma in a family member provides an important opportunity to intervene with others in that family," the researchers state. They conclude: "This intervention may provide a useful foundation for future efforts to target the more than half million siblings at risk for melanoma, a lethal but preventable disease."

SOURCE: Cancer

 
 
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