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Recent News and Articles on the Keywords: of gastrointestinal + outbreak scenario + scenario  Related to the article below (Last Update: 5/13/2008)

JNJ: Tapentadol Showed Higher Gastrointestinal Tolerability
CNNMoney.com - May 9, 2008
Johnson & Johnson (JNJ) said a Phase III study of Tapentadol immediate release tablets showed improved gastrointestinal tolerability compared with oxycodone ...
New Study Suggests Tapentadol IR for Acute Pain Is Associated With ... PR Newswire (press release)
Results of Phase 3 Study Show Tapentadol IR Relieves Acute Pain ... Earthtimes (press release)
all 14 news articles »  JNJ
DOR BioPharma Announces Appointment of Christopher J. Schaber, PhD ...
CNNMoney.com - May 9, 2008
Oral BDP may also have application in treating other gastrointestinal disorders characterized by severe inflammation. DOR has initiated a development ...OTC:DORB
New Data Show High Frequency of Medical Claims for ...
PR Newswire (press release), NY - May 6, 2008
The retrospective study reported today tracked insurance claims for gastrointestinal adverse events among more than 368000 patients in the 12 months ...
'People foods' that can kill your pet
MSNBC - May 9, 2008
Although these foods are normally harmless, some animals have sensitive gastrointestinal tracts. So even these healthy treats should be avoided if they ...
Gastrointestinal Disease and Carbohydrate Nutrition in Horses
TheHorse.com, KY - May 5, 2008
He pointed out that maintaining stability of the hindgut microbial community is of paramount importance to gastrointestinal (GI) health. ...
FDA delays decision again on Adolor drug
Bizjournals.com, NC - May 9, 2008
Adolor Corp. said Friday that the Food and Drug Administration will not issue an action letter regarding the company's Entereg gastrointestinal drug by ...
Adolor says FDA delays decision on bowel drug Entereg Houston Chronicle
FDA again delays decision on Adolor drug Trading Markets (press release)
all 26 news articles »  ADLR
ARYx Reports First Quarter 2008 Financial Results
Business Wire (press release), CA -
Each of these agents is in Phase 2 clinical trials and include our prokinetic agent for the treatment of various gastrointestinal disorders, ATI-7505, ...ARYX
Nitrates In Vegetables Protect Against Gastric Ulcers, Study Shows
Science Daily (press release) - May 8, 2008
They have the major disadvantage of causing a large number of serious side effects in the form of bleeding and ulcers in the gastrointestinal tract. ...
The effect of salatrim, a low-calorie modified triacylglycerol, on ...
Am J Clin Nutr (subscription), CA - May 9, 2008
In addition, it has been hypothesized that salatrim's reduced absorption in the small intestine may lead to greater amounts of fat in the gastrointestinal ...
GATTEX(TM) Abstracts Accepted for Presentation at DDW Conference ...
Centre Daily Times, PA - May 8, 2008
Accepted abstracts will also be published in the supplements to the April issues of either Gastroenterology or GIE: Gastrointestinal Endoscopy. ...NPSP
Source: Google News

Syndromic Surveillance: The Case for Skillful Investment -
DM Sosin - Biosecurity and Bioterrorism: Biodefense Strategy, Practice, …, 2003 - liebertonline.com
... and prospective detection of outbreaks and clusters of gastrointestinal illness
and ... among agent, host, and environmental factors in an outbreak scenario. ...

A Systems Overview of the Electronic Surveillance System for the Early Notification of Community- … -
J Lombardo, H Burkom, E Elbert, S Magruder, SH … - Journal of Urban Health: Bulletin of the New York Academy of …, 2003 - ingentaconnect.com
... Respiratory ? Gastrointestinal ? Fever ? Dermatological ... The approach taken by ESSENCE
II is to develop several outbreak scenarios to test the performance ...

[PDF] A METHOD FOR EVALUATING OUTBREAK DETECTION IN PUBLIC HEALTH SURVEILLANCE SYSTEMS THAT USE … -
DL Buckeridge - 2005 - bmir.stanford.edu
... 2.2 Example respiratory and gastrointestinal data series . . ... 5.9 Earliest clinical
diagnosis by release scenario. . ... 5.12 Timing of outbreak detection algorithm ...

[PDF] Syndromic surveillance in public health practice, New York City. -
R Heffernan, F Mostashari, D Das, A Karpati, M … - Emerging Infectious Diseases, 2004 - cdc.gov
... agreement for the syndromes of respi- ratory and gastrointestinal illness (12 ... of
spatial signals, or simula- tion studies with outbreak scenarios and ?spiked ...
-

Evaluating statistical methods for syndromic surveillance -
MA Stoto, RD Fricker Jr, A Jain, A Diamond, JO … - Statistical Methods in Counterterrorism: Game Theory, … - Springer
... For gastrointestinal illness, the teams typically were able to ... exposed by the time
that the outbreak was detected. ... to be less sensitive to some other scenario. ...

Surveillance of ambulance dispatch data as a tool for early warning -
KH Bork, BM Klein, K M?lbak, S Trautner, UB … - Euro Surveill, 2006 - eurosurveillance.org
... scheme for influenza and influenza-like illness and a detection system for outbreaks
of gastrointestinal illness such as ... Scenario I: Outbreak of tularaemia ...

Disease outbreak detection system using syndromic data in the greater Washington DC area -
MD Lewis, JA Pavlin, JL Mansfield, SO?Brien, LG … - American Journal of Preventive Medicine, 2002 - Elsevier
... to many natural or unnatural disease outbreak scenarios. ... or fever, while an outbreak
of smallpox ... a patient presenting with a gastrointestinal complaint might ...

Dennis M. Perrotta
A FICTIONAL, BUTP SCENARIO - Emerging Infectious Diseases: Trends and Issues, 2002 - books.google.com
... M. Perrotta A FICTIONAL, BUT PLAUSIBLE SCENARIO /(had been ... Gastrointestinal anthrax
results ... to be the cause of the 1979 Sverdlovsk outbreak previously described ...
-

HISTORY OF BIOLOGICAL WARFARE -
CB AGENTS, E PRINCIPLES, SOF BIOTERRORISM - Proc (Bayl Univ Med Cent), 2001 - pubmedcentral.nih.gov
... especially with fever, respiratory, or gastrointestinal complaints; ... hoax. The most
common scenario for bioterrorism ... During a massive outbreak, local laboratories ...

[PDF] A Gut Feeling -
VGI Infections - Canadian Journal, 2004 - stacommunications.com
... environmental cleaning beyond routine practices or staff exclusion policies are
necessary during a norovirus outbreak scenario is unknown. ... Viral GI Infections ...

Source: Google Scholar

Scientists seek to assess the microbial risks in the water we drink

 

It is a familiar scenario experienced around the world: an outbreak of gastrointestinal illness suddenly emerges in a community, and no one knows where it came from or how to stop it. At the start of the outbreak, only a few people are affected, most often the very old and the very young. As the outbreak worsens, more and more people fall ill, and people who were weak or unwell may develop life-threatening complications.

Such outbreaks sometimes originate from a source that most people in the United States and other developed countries trust unquestioningly: drinking water. However, there is much we do not know about the causes and likelihood of waterborne illness, and we can and should do more to assess the risks, according to a new report, Clean Water: What is Acceptable Microbial Risk", released by the American Academy of Microbiology.

“In the developing world, where diarrheal illnesses claim roughly 2 million lives each year, access to clean water is a serious public health challenge,” says Mark LeChevallier of American Water Works Service Company in Vorhees, New Jersey, one of the authors of the report. “Fortunately, the United States and other developed countries have managed to rein in the biggest waterborne disease problems, but water quality is still a very real concern. Sporadic illnesses and outbreaks still occur, and they can have a serious impact on public health and commerce.”

The report focuses on microbial risk assessment, a relatively new tool for addressing the problems of waterborne infectious diseases that provides a formal process for quantifying the health risks from pathogenic microorganisms.

“Microbial risk assessment is an evolving field, and it requires an interdisciplinary, collaborative approach,” LeChevallier explains. “Much more research is needed to fill gaps in our understanding of waterborne pathogens and to determine the current rate of waterborne illness.”

The report is the result of a colloquium convened by the American Academy of Microbiology in October, 2006. Experts in diverse fields with expertise in water quality and analysis – including microbiology, public health, engineering, epidemiology, medicine, and water science – discussed some of the controversial topics in microbial risk assessment, research that could move the field forward, and the need for increased training and better communication with the public. The report is a record of their discussions and recommendations.

During an outbreak situation, scientists and public health officials have many questions to address. Which water treatment option is best" Who are the most sensitive members of the population, and how can they be protected" Where should efforts and resources be directed" What are the most dangerous pathogens found in the water, and how did they get there"

Microbial risk assessment addresses all these questions by offering a formalized approach for identifying the risks that arise from contact with pathogenic microorganisms, including certain bacteria, viruses, and microscopic eukaryotes. Microbial risk assessment also can help guide management decisions, identify sensitive groups, spot critical pathogen control points, and aid in the assessment of the adequacy of drinking water treatment barriers.

The report describes the scientific methods involved in microbial risk assessment, addresses the current challenges facing this evolving field, and offers a number of recommendations, including:

  • An international database of pathogen occurrence in drinking water and ambient waters should be established. This would inform microbial risk assessment, risk management, and enable the implementation of effective public health initiatives.

  • An independent microbial risk assessment advisory board with members from both industry and academia, and with international representation, should be assembled. This advisory board could foster the most consistent use of the best techniques for evaluating the problems of public health and ambient water.

  • The general public needs to know basic information about their source and treatment of drinking water, the need for future treatment upgrades and infrastructure enhancements, and the fundamentals of microbial risk.

  • Additional research is needed to validate numerical guidelines, such as the EPA’s microbial water guidance of one illness per 10,000 individuals in a given year. Numerical guidelines are useful, but may not be suitable for all water exposures.

  • Microbial risk assessment needs to broaden the use of available epidemiologic data. Studies are needed to integrate outbreak data to better estimate microbial infectivity under real-world conditions.

###

A full copy of the report and further recommendations can be found on the Academy website at www.asm.org/colloquia. Ninety-second pod casts, originally aired as part of the American Society for Microbiology’s radio series, are available for download at this website. To receive a printed copy of Clean Water: What is Acceptable Microbial Risk", email the Academy at colloquia@asmusa.org.

The American Academy of Microbiology is the honorific leadership group of the American Society of Microbiology. The mission of the Academy is to recognize scientific excellence, as well as foster knowledge and understanding in the microbiological sciences. For more information about the American Society for Microbiology, contact Barbara Hyde at 202-942-9206 or visit www.asm.org

 
 
 
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