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Recent News and Articles on the Keywords: mole mapping + melanoma may + melanoma  Related to the article below (Last Update: 5/13/2008)


Thread
Got you under my skin
Thread, New Zealand - Apr 22, 2008
Dr Vincent Crump is a renowned Allergist and Consultant Physician specialising in skin analysis, mole assessment and mole mapping at LaserDerm. ...

MediaPost Publications
Trends Point The Way To Goji Berries, Gluten-Free Comestibles
MediaPost Publications, New York - May 8, 2008
The group's "Culinary Trend Mapping" report says future trends can be extrapolated from current products like green tea, pomegranate, sea salt or chipotle. ...
The Ultimate What's Hot, What's Not Culinary Trend Report
Earthtimes (press release), UK - May 2, 2008
Other trends, such as mole, manchego cheese and pho, haven't moved as quickly, though they are not down for the count. With growing interest in ...
The platypus: a living quilt of genetic oddities
Los Angeles Times, CA - May 8, 2008
After all, they have mole's fur, a duck's bill and venomous spurs on their legs. But now we know what a pastiche of mammalian, avian and reptilian features ...
Source: Google News

Familial atypical multiple mole-melanoma syndrome -
HT Lynch, BC Frichot? - British Medical Journal, 1978 - jmg.bmj.com
... ARTICLES. Familial atypical multiple mole-melanoma syndrome. ... This cutaneous phenotype
signifying melanoma risk may now be added to an increasing body of ...

A Major Quantitative-Trait Locus for Mole Density Is Linked to the Familial Melanoma Gene CDKN2A: A … -
G Zhu, DL Duffy, A Eldridge, M Grace, C Mayne, LO' … - The American Journal of Human Genetics, 1999 - Elsevier
... variant itself and its effect on melanoma risk might ... quite distinct etiologies for
these two mole types. ... Finally, using linkage mapping with a highly heritable ...

Familial cutaneous malignant melanoma: autosomal dominant trait possibly linked to the Rh locus. -
MH Greene, LR Goldin, WH Clark Jr, E Lovrien, KH … - Proceedings of the National Academy of Sciences of the …, 1983 - pubmedcentral.nih.gov
... the short arm of chromosome 1, within 30 map units of ... Melanome und atypische
disseminierte Pigmentale (BK-Mole-Syndrom ... Hereditary aspects of malignant melanoma. ...

… 2 A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families -
HT Lynch, RE Brand, D Hogg, CA Deters, RM Fusaro, … - Cancer, 2002 - doi.wiley.com
... Pancreatic carcinoma may be an integral tumor in several hereditary cancer syndromes ...
10,11 and 5) the familial atypical multiple mole melanoma (FAMMM) syndrome 3 ...

… of acquired melanocytic nevi in white children. A comparison with melanoma: the Vancouver Mole … -
RP Gallagher, DI McLean, CP Yang, AJ Coldman, HK … - Archives of Dermatology, 1990 - Am Med Assoc
... A comparison with melanoma: the Vancouver Mole Study. ... exposure to strong intermittent
sunlight in childhood (a risk factor for cutaneous melanoma) may also be ...

DELETION MAPPING OF CHROMOSOME REGION 9p21-p22 SURROUNDING THE CDKN2 LOCUS IN MELANOMA -
JAS Michael MASTRANGELO, CMC SHIELDS - Int. J. Cancer, 1996 - doi.wiley.com
... 15 Dutch familial atypical multiple mole-melanoma syndrome pedigrees ... The present
results of deletion mapping at 9p21 ... of more than one melanoma tumor suppressor ...

Evidence against the reported linkage of the cutaneous melanoma-dysplastic nevus syndrome locus to … -
LA Cannon-Albright, DE Goldgar, EC Wright, A Turco … - American Journal of Human Genetics, 1990 - pubmedcentral.nih.gov
... Mapping the gene for hereditary cutaneous malignant melanoma-dysplastic ... precursor
lesions of superficial spreading and nodular melanoma. ... The BK mole syndrome'. ...

The Transformation Rate of Moles (Melanocytic Nevi) Into Cutaneous Melanoma A Population-Based … -
H Tsao, C Bevona, W Goggins, T Quinn - Archives of Dermatology, 2003 - Am Med Assoc
... any given mole will turn into a melanoma. ... within MN, photographic documentation
("mole mapping") of all ... Targeted mapping of older individuals (at least older ...

Further evidence for a locus for cutaneous malignant melanoma-dysplastic nevus (CMM/DN) on … -
AM Goldstein, NC Dracopoli, EC Ho, MC Fraser, KS … - American Journal of Human Genetics, 1993 - pubmedcentral.nih.gov
... The BK mole syndrome ... The CEPH consortium linkage map of human chromosome 1. Genomics ...
Linkage analysis of melanoma alone and chromosome 1p markers PND, D1S47, and ...

A Locus Linked to p16 Modifies Melanoma Risk in Dutch Familial Atypical Multiple Mole Melanoma ( … -
PA van der Velden, LA Sandkuijl, W Bergman, E … - Genome Research, 1999 - Cold Spring Harbor Lab
... candidate region for further gene mapping in p16 ... search for risk modifiers in melanoma
development ... The familial atypical multiple mole melanoma (FAMMM) syndrome ...

Source: Google Scholar

"Mole mapping" may help people spot melanoma

NEW YORK (Reuters Health) - Few people follow experts' advice to regularly inspect their skin for signs of cancer, and even fewer do it thoroughly and accurately. But a new study suggests that a simple diagram of the body could help.

Researchers found that people who "mapped" their moles on a drawing of the torso were better able to catch new growths than their peers who relied on visual memory alone. In this case, the new growths were merely computer manipulations of digital photographs of the study participants' backs. But in real life, a simple mole-mapping diagram could help people find melanoma early, according to Dr. Martin A. Weinstock, the study's senior author.

The best way to detect melanoma is through regular, thorough self-exams of the skin, looking for new growths or changes in the size, shape or color of existing moles. But most people neither regularly nor thoroughly inspect their skin, Weinstock told Reuters Health.

"It's there to see," he said, "but you have to look, and you need to do it systematically."

To help people do that, Weinstock and his colleagues at Brown University Medical School in Providence, Rhode Island, came up with the idea of "mole mapping" -- giving patients a simple drawing of the body on which they can mark the location of existing moles, then hopefully catch any new growths when they arise.

For the current study, reported in the Journal of the American Academy of Dermatology, the researchers gave 88 men and women instructions on how to do a skin self-exam, then asked them all to perform one before a follow-up visit two weeks later.

Half of the study participants also received a diagram of the back to help them document their moles. The rest served as a comparison group.

When they returned for their follow-up visit, participants were shown digital photos of their backs that had been taken at their initial visit. They were told that some pictures had been manipulated and some had not; their task was to identify what, if any, changes had been made in each photo.

In the end, 52 percent of the diagram group correctly assessed their photos, versus 33 percent of the comparison group. In instances where a skin growth had been added to the photo, 60 percent of the diagram group caught it, while, again, only 33 percent of the comparison group gave an accurate judgment.

A thorough skin exam includes using full-length and hand mirrors to see the back of the body, and inspecting easily forgotten areas like the scalp, the soles of the feet and the skin between the toes.

Ideally, skin self-exams should be performed once a month, Weinstock said. When melanoma is caught in its earliest stages, he noted, the disease has a 95 percent survival rate. The survival odds plummet, however, once the cancer has spread to other parts of the body.

SOURCE: Journal of the American Academy of Dermatology, August 2006.

Copyright © 2006 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

Plastic surgeons have new device for midface lifts

NEW YORK (Reuters Health) - A device used to help plastic surgeons perform lifts of the midface area produces good results, according to the results of a pilot study.

The device, called the Endotine ST, is used to stabilize the soft tissue in the cheekbone area after the surgeon has separated it from the ligaments connecting it to the bone and lifted it into a new position. It attaches to soft tissue with tiny blunt-tipped tines, after which two "leashes" are sutured into the tissue to anchor it in place. The device is then absorbed into the body over several months, and completely disintegrates, according to animal studies.In the July/August issue of the Archives of Facial Plastic Surgery, Dr. James Newton of Stanford University Medical Center in California reports on the results of midface lifts using the device in 10 patients. At the time of the study, Newton served on the physician advisory board of Coapt Systems, Inc., in Palo Alto, the company that makes the Endotine ST.

Nine of the 10 patients reported significant improvements in their appearance by six months after the procedure, Newton reports. One patient stated that the procedure did not improve her appearance at all; this could have been due to a tear in the suture used to anchor the Endotine ST's leash, which would have allowed the soft tissue to drop to its original position, he suggests. Using two sutures rather than one for each leash appears to have alleviated that problem, Newton writes.

Patients had less major swelling and nerve weakness than is typically seen with traditional face-lifts, which use sutures to anchor soft tissue, according to Newton. They did experience some tenderness and swelling of the cheek area in the weeks after the procedure. One patient developed a paralysis of a facial nerve that disappeared by three months after the procedure. None of the patients had infections or skin irregularities.The main benefit of the procedure is a redistribution of the volume of the fat pads over the cheeks, so the procedure is particularly appropriate for patients with sagging in this area, he notes.The device also reduces the risk that a physician will accidentally entrap a nerve in a suture, Newton said.

"The adjustability and decreased risk of nerve entrapment to the overlying soft tissues makes the Endotine ST device another option for safe and secure stabilization of a properly mobilized midface," he concludes.
 
 
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