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Recent News and Articles on the Keywords: ddt exposure + liver cancer + ddt  Related to the article below (Last Update: 5/13/2008)

Unwelcome Guest: PBDEs in Indoor Dust
Food Consumer, IL - May 1, 2008
Some researchers wonder if there could be a connection between PBDE exposure and thyroid cancer, a disease that disproportionately affects women. ...

The Canadian Press
Environmental exposures can have an impact on whether men's 'boys ...
The Canadian Press, TORONTO - Apr 21, 2008
Certain environmental exposures - including heavy metals, organic solvents and some pesticides such as DDT - have been a focus of attention as well. ...
The Global Pesticide Pushers in Latin America
RedOrbit, TX - Apr 24, 2008
He says the group found that four of the 14 pesticides that are officially banned in Bolivia-Aldrin, DDT, Folidol and Endrin- continue to be sold in the ...
Source: Google News

THE HUMAN HEALTH EFFECTS OF DDT (DICHLORODIPHENYLTRICHLOROETHANE) AND PCBS (POLYCHLORINATED … -
MP Longnecker, WJ Rogan, G Lucier - Annual Reviews in Public Health, 1997 - Annual Reviews
... As with DDT, exposure is ongoing owing to accumulation ... consistently associated with
abnormal liver function tests ... also found that occupational exposure to PCBs ...

Cancer mortality and environmental exposure to DDE in the United States. -
P Cocco, N Kazerouni, SH Zahm - Environmental Health Perspectives, 2000 - pubmedcentral.nih.gov
... The association between liver cancer and DDE observed ... of dichloro-diphenyl-
trichloroethane (DDT) workers: a ... Hayward D. Organochlorine exposure estimation in ...

Dichlorodiphenyltrichloroethane (DDT): ubiquity, persistence, and risks. -
V Turusov, V Rakitsky, L Tomatis - Environmental Health Perspectives, 2002 - pubmedcentral.nih.gov
... V, Charles RT, Boiocchi M, Gati E. Liver tumours in CF ... L, Huff J. Evidence of
carcinogenicity of DDT in nonhuman ... RT, Boicchi M. Effect of long-term exposure to ...

Pesticides and Breast Cancer Risk: A Review of DDT, DDE, and Dieldrin -
SM Snedeker - Environmental Health Perspectives, 2001 - pubmedcentral.nih.gov
... latipes) following egg microinjection of o,p'-DDT. ... P. Risk of breast cancer and
organochlorine exposure. ... of organochlorines in human brain, liver, and adipose ...

Pesticides and cancer -
J Dich, SH Zahm, A Hanberg, HO Adami - Cancer Causes and Control, 1997 - Springer
... 1 In mice, the exposure to p,p-DDT increased the ... 48 The increase in liver tumor
incidence among DDT-exposed animals has been confirmed in many studies. ...

DDT mimicks estradiol stimulation of breast cancer cells to enter the cell cycle -
C Dees, M Askari, JS Foster, S Ahamed, J … - Molecular Carcinogenesis, 1997 - doi.wiley.com
... in ER-negative HS 578Bst breast cancer cells or in rat liver epithelial cells. ...
Therefore, the cancer risks associated with DDT exposure may be ...

… (DDT) and 1, 1-Dichloro-2, 2-bis (p-chlorophenyl) ethylene (DDE) and Risk of Primary Liver Cancer -
KA McGlynn, CC Abnet, M Zhang, XD Sun, JH Fan, TR … - jnci, 2006 - jnci.oxfordjournals.org
... reports, a Swedish study that interviewed relatives of deceased cases and control
subjects reported no association between DDT exposure and liver cancer (26). ...

Effects of long-term oral administration of DDT on nonhuman primates -
S Takayama, SM Sieber, DW Dalgard, UP Thorgeirsson … - Journal of Cancer Research and Clinical Oncology, 1999 - Springer
... species variation in response to DDT exposure (Chabra and ... early hepatic changes caused
by DDT in rats ... focal ne- crosis and regenerative liver response (Kostka ...

Loss of gap junctions from DDT-treated rat liver epithelial cells -
RJ Ruch, WJ Bonney, K Sigler, X Guan, D Matesic, … - Carcinogenesis, 1994 - Oxford Univ Press
... M. (1987) Effect of in vivo exposure to the liver tumor promoters phenobarbital
or DDT on the gap ... connexin32 during tumor promotion in rat liver and its ...

Pesticide exposure: human cancers on the horizon. -
K Jaga, D Brosius - Rev Environ Health, 1999 - ncbi.nlm.nih.gov
... DDT administration and lymphoma, respiratory cancer, liver cancer, and estrogenic ...
as multiple chemical exposure, lifestyle factors ... of data on DDT toxicity from ...

Source: Google Scholar

DDT exposure linked to liver cancer in humans

NEW YORK (Reuters Health) - High blood levels of the pesticide DDT are associated with an elevated risk of liver cancer, according to the results of a study conducted in China.

Previous reports have linked DDT and its breakdown product DDE with liver tumors in laboratory animals. Whether exposure to this pesticide is associated with liver cancer in humans, however, has been less clear. To investigate, Dr. Katherine A. McGlynn, from the National Cancer Institute in Rockville, Maryland, and colleagues analyzed data from 168 "case" patients with liver cancer and 385 age- and sex-matched healthy controls who participated in the Nutritional Intervention Trials in Linxian. DDT and DDE serum levels were measured using gas chromatography-mass spectrometry.

The risk of liver cancer was directly related to the DDT serum level, McGlynn's group reports in the current Journal of the National Cancer Institute. Subjects in the highest DDT quintile were nearly four times more likely to develop liver cancer than those in the lowest quintile.

The DDE level alone was not significantly associated with liver cancer risk. However, in conjunction with a high DDT level, a low DDE level appeared to increase the risk further.

In terms of absolute risk, the highest DDT quintile was tied to a liver cancer rate of 46 cases per 100,000 persons per year compared with a rate of 26 cases per 100,000 persons per year for the lowest quintile.

The results suggest that DDT exposure may be a risk factor for the development of liver cancer in humans, "especially in populations that are directly exposed to DDT, rather than just exposed to its metabolites," the authors conclude.

A glass of wine a day may protect the aging heart

NEW YORK (Reuters Health) - Data from the Cardiovascular Health Study show that moderate alcohol consumption may reduce risk of heart failure among older adults, researchers report in the Journal of the American College of Cardiology.

The ongoing study was launched in 1989 to follow the health status of Medicare recipients living in communities across the country. Dr. Chris L. Bryson of the University of Washington, Seattle, and associates investigated whether there was an association between moderate alcohol consumption -- defined as one to six drinks a week -- and the risk of congestive heart failure in 5,888 subjects who were at least 65 years old. The subjects were followed for 7 to 10 years.There were 5,595 subjects at risk for heart failure at baseline and 1056 events occurred during follow-up.

During follow up, moderate drinkers had about an 18 percent lower risk of developing heart failure than abstainers. Those consuming 7 to 10 drinks per week had a 34 percent lower risk of heart failure.

 

 

 

 

 

 
 
 
 
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