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Recent News and Articles on the Keywords: may not + sinus infections + effective  Related to the article below (Last Update: 5/5/2008)


Wilkes Barre Times-Leader
Ancient and simple sinus cleaners work ASK DR. H MITCHELL HECHT
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And when endodontic treatment (root canal therapy) is not effective, endodontic surgery may be able to save the tooth." Question: I'm trying to get on the ...
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Attempts at eliminating the "carrier" status are not very effective - and even when successful, recolonization by the bacteria is common. ...
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Belleville News Democrat,  USA - Apr 15, 2008
The clinics treat about 25 to 30 common ailments such as cold and flu, sinus, ear and bladder infections, pinkeye, allergies, minor burns and rashes, ...
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Scotts Valley Banner, CA - Apr 11, 2008
Nasal stuffiness from allergic rhinitis can cause swelling and obstruction of the sinuses, which can cause a bacterial sinus infection. ...

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Source: Google News

Acute sinusitis: a cost-effective approach to diagnosis and treatment -
LJ Fagnan - Am Fam Physician, 1998 - aafp.org
... Imaging studies are not cost effective in the initial ... Radiographs, however, may be
helpful in uncertain or recurrent ... A normal sinus x-ray series has a negative ...
-

Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta- … -
SD de Ferranti, JP Ioannidis, J Lau, WV Anninger, … - BMJ, 1998 - pubmedcentral.nih.gov
... and ?sinusitis,? we searched Medline up to May 1998 for ... to doctors because primary
care practitioners do not routinely obtain sinus films for ...

Associations of Symptoms and Health-Related Quality of Life: Findings from a National Study of … -
KA Lorenz, MF Shapiro, SM Asch, SA Bozzette, RD … - Annals of Internal Medicine, 2001 - annals.highwire.org
... In addition, headache and sinus symptoms were ... oral herpes simplex virus infection,
and aphthous ... unless specifically elicited and therefore may not be addressed ...

Antimicrobial Use in Long-Term-Care Facilities -
LE Nicolle, DW Bentley, R Garibaldi, EG Neuhaus, … - Infection Control and Hospital Epidemiology, 2000 - UChicago Press
... In the LTCF, culture results may not be available or may be delayed, often ... Sinus
infection CT (refractory only) TMP-SMX+amoxicillin, cefuroxime axetil ...

Fourth Branchial Pouch Sinus: Principles of Diagnosis and Management. -
MS Godin, DB Kearns, SM Pransky, AB Seid, DB … - The Laryngoscope, 1990 - laryngoscope.com
... that a portion of the thymus may actually be ... A recurrent left neck abscess that does
not respond to ... an anomalous tract originating at the left pyriform sinus. ...

Sinusitis -
ER Wald - Pediatrics in Review, 1993 - Am Acad Pediatrics
... The frontal sinus is not a frequent site of infection, but may be a focus for
spread of infection to the orbit or central nervous system. ...

Controlled study of fluconazole in the prevention of fungal infections in neutropenic patients with … -
ME Ellis, H Clink, P Ernst, MA Halim, A Padmos, D … - European Journal of Clinical Microbiology & Infectious …, 1994 - Springer
... for ARUNF, but includes patients who may have an ... pulmo- nary: cough, dyspnoea, sputum;
sinus: headache, facial ... radiological signs and fever not responding to ...

One-Year Follow-up of Symptoms of Gastroesophageal Reflux During Infancy -
SP Nelson, EH Chen, GM Syniar, KK Christoffel - Pediatrics, 1998 - Am Acad Pediatrics
... to experience an increased frequency of ear, sinus, or upper ... of pH-proven GER, but
this may not be feasible ... The data reported do not address whether physicians ...

Lumbar and thoracic epidural blood injections to treat spontaneous intracranial hypotension -
HT Benzon, R Nemickas, RE Molloy, S Ahmad, O Melen … - Anesthesiology, 1996 - anesthesiology.org
... head or neck trauma, or sinus infection experienced a ... oncotic pressures across the
venous sinus and arachnoid ... first patient or the blood may not have reached ...

The medical management of rhinosinusitis -
MS BENNINGER, J ANON, RL MABRY - Otolaryngology-Head and Neck Surgery, 1997 - Elsevier
... middle meatus under endoscopic guidance may provide useful ... long-term outcome after
endoscopic sinus surgery than ... Although allergy has not been fully shown to ...

Source: Google Scholar

Some Common Treatments for Sinus Infections May Not Be Effective

A comparison of common treatments for acute sinusitis that included an antibiotic and a topical steroid found neither more effective than placebo, according to a study in the December 5 issue of JAMA.

Acute sinusitis (sinus infection) is a common clinical problem with symptoms similar to other illnesses, and is often diagnosed and treated without clinical confirmation. Despite the clinical uncertainty as to a bacterial cause, antibiotic prescribing rates remain as high as 92 percent in the United Kingdom and 85 percent to 98 percent in the United States, according to background information in the article. “Because there are no satisfactory studies of microbiological etiology from typical primary care patient practices, wide-scale overtreatment is likely occurring,” the authors write. Concerns about wide-spread antibacterial use include increasing antibiotic resistance in the community. Anti-inflammatory drugs such as topical steroids are also used as a treatment and may be beneficial, but there has been limited research.

Ian G. Williamson, M.D., of the University of Southampton, England, and colleagues conducted a double-blind randomized placebo-controlled trial to determine the effectiveness of the antibiotic amoxicillin and topical steroid budesonide in acute maxillary sinusitis (rhinosinusitis; inflammation of the nasal cavity and sinuses). The study included 240 adults with acute nonrecurrent sinusitis treated at 58 family practices between November 2001 and November 2005. Patients were randomized to 1 of 4 treatment groups: antibiotic and nasal steroid (500 mg of amoxicillin 3 times per day for 7 days and 200 μg of budesonide in each nostril once per day for 10 days); placebo antibiotic and nasal steroid; antibiotic and placebo nasal steroid; placebo antibiotic and placebo nasal steroid.

The researchers found that the proportions of patients with symptoms lasting 10 or more days were 29 of 100 (29 percent) for amoxicillin vs. 36 of 107 (33.6 percent) for no amoxicillin; and 32 of 102 (31.4 percent) for topical budesonide vs. 33 of 105 (31.4 percent) for no budesonide. Secondary analysis suggested that nasal steroids were significantly more effective in patients with less severe symptoms at baseline.

“Our main conclusions are that among patients with the typical features of acute bacterial sinusitis, neither an antibiotic nor a topical steroid alone or in combination are effective in altering the symptom severity, the duration, or the natural history of the condition. Topical steroids are likely to be effective in those with such features but who have less severe symptoms at presentation to the physician,” the authors write.

(JAMA. 2007;298(21):2487-2496. Available pre-embargo to the media at www.jamamedia.org)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Editorial: Acute Sinusitis—To Treat or Not to Treat?

In an accompanying editorial, Morten Lindbaek, M.D., of the University of Oslo, Norway, comments on the findings regarding treating acute sinusitis.

“The study by Williamson et al has implications for clinicians who treat patients with acute sinusitis–like symptoms. This study reinforces the lack of benefit from antibiotics shown in a number of other studies that recruited patients based on clinical symptoms and findings. Most patients with acute purulent sinusitis recover without antibiotic treatment, as was also observed in a study that used sinus computed tomography scans as the diagnostic standard. But some patients with sinusitis are more ill than others with fever, malaise, and deteriorated general condition. These patients still are in need of antibiotics, although they are relatively uncommon in general practice. So far there is no reliable way to distinguish viral sinusitis from bacterial sinusitis in the general practice setting, and a point of care test that could single out patients who could benefit from antibiotic treatment is not available.”

(JAMA. 2007;298(21):2543-2544. Available pre-embargo to the media at www.jamamedia.org)

Editor’s Note: Please see the article for additional information, including other financial disclosures, funding and support, etc.
 
 
 
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