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Recent News and Articles on the Keywords: dialysis patients + patients + dialysis  Related to the article below (Last Update: 5/13/2008)

Dialysis patients petition hospital to protest hospital parking fees
Peterborough Examiner, Canada -
Dialysis ?is not a cure, only a treatment,? he said. Goldman sent a petition to PRHC signed by 14 dialysis patients protesting the parking fees because many ...
New Data At ERA-EDTA Show Mimpara(R) (Cinacalcet) Improves ...
Medical News Today (press release), UK -
Amgen (Europe) GmbH announced results from the Evaluation of the Clinical Use of Mimpara in Haemodialysis and Peritoneal Dialysis Patients, an Observational ...
Ark. dialysis clinic keeps pumping despite tornado
Pine Bluff Commercial, AR -
Inside the dark-brick building, the clinic's patients sat in cooled 72-degree air as dialysis machines pumped blood out of their bodies, through a cleaning ...
Ark. dialysis clinic keeps pumping despite tornado
WREG, TN -
AP - May 12, 2008 7:54 PM ET STUTTGART, Ark. (AP) - Officials of a kidney dialysis center at Stuttgart have made sure their patients lives aren't completely ...
1 dies, 1 ill after receiving kidneys
Boston Globe, United States -
"But, on the other hand, we see patients who die every day on dialysis" awaiting a kidney transplant, he said. The 57-year-old man transplanted at Hanto's ...
Vitamin D Keeps Kidney Patients Alive
Ivanhoe, FL - May 11, 2008
In addition, the results suggest treatment with activated vitamin D can offer CKD patients who are not yet on dialysis a better chance of survival. ...
PATIENTS WALK IN TO SEE DOCTOR 12 HOURS EVERY DAY
Derby Evening Telegraph, UK -
Richard Henley is a kidney dialysis patient in Ilkeston whose condition means he occasionally needs to see a doctor urgently. ...

Earthtimes (press release)
NxStage Medical Reports First Quarter 2008 Results
PR Newswire (press release), NY -
Safety needles are essential products used to access patients' blood during the vast majority of chronic dialysis therapy treatments. ...
NxStage Medical Reports First Quarter 2008 Results Biloxi Sun Herald
all 454 news articles »  NXTM
Kidney dialysis helps patients by cleaning their blood
Sun Shopper, AZ - May 9, 2008
Dialysis is now a standard treatment around the world. The federal government pays 80 percent of all dialysis costs for most patients. ...
New Data at ERA-EDTA Show Mimpara(R) (Cinacalcet) Improves ...
InfoBolsa, Spain - May 11, 2008
Mimpara is the first and only calcimimetic agent approved for use in dialysis patients to specifically bind to and directly modulate the calcium-sensing ...
Source: Google News

… of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and … -
RA Wolfe, VB Ashby, EL Milford, AO Ojo, RE … - New England Journal of Medicine, 1999 - content.nejm.org
... Next Next. Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis
Awaiting Transplantation, and Recipients of a First Cadaveric Transplant. ...

Death risk in hemodialysis patients: the predictive value of commonly measured variables and an …
EG Lowrie, NL Lew - Am J Kidney Dis, 1990 - ncbi.nlm.nih.gov
... Therefore, we suggest that strategies designed to improve the overall mortality
statistic for dialysis patients in the United States would be better directed ...

… calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. -
GA Block, TE Hulbert-Shearon, NW Levin, FK Port - Am J Kidney Dis, 1998 - ncbi.nlm.nih.gov
... the distribution of serum phosphorus in two large national, random, cross-sectional
samples of hemodialysis patients who have been receiving dialysis for at ...

Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. -
J Zimmermann, S Herrlinger, A Pruy, T Metzger, C … - Kidney International, 1999 - pt.wkhealth.com
... Recently, Koch et al have found that low apo AI is an independent predictor of cardiac
and noncardiac death in 412 diabetic dialysis patients [12]. ...

… beam computed tomography in the evaluation of cardiac calcification in chronic dialysis patients. -
J Braun, M Oldendorf, W Moshage, R Heidler, E … - Am J Kidney Dis, 1996 - ncbi.nlm.nih.gov
Am J Kidney Dis. 1996 Mar;27(3):394-401. Electron beam computed tomography in the
evaluation of cardiac calcification in chronic dialysis patients. ...

C-Reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients. -
JY Yeun, RA Levine, V Mantadilok, GA Kaysen - Am J Kidney Dis, 2000 - ncbi.nlm.nih.gov
... jyyeun@ucdavis.edu Hypoalbuminemia predicts death in dialysis patients. ... We measured
CRP and albumin levels in October 1995 in 91 hemodialysis (HD) patients. ...

Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. -
GM Chertow, SK Burke, P Raggi - Kidney International, 2002 - pt.wkhealth.com
... 280,000 patients undergoing dialysis for end-stage renal disease (ESRD) in the United
States [1]. The annual mortality rate in dialysis patients is in excess ...

Congestive heart failure in dialysis patients: Prevalence, incidence, prognosis and risk factors -
JD Harnett, RN Foley, GM Kent, PE Barre, D Murray, … - Kidney Int, 1995 - nature.com
... 10.1038/ki.1995.132. Congestive heart failure in dialysis patients: Prevalence,
incidence, prognosis and risk factors. John D Harnett ...

… , nutritional status, and cardiovascular disease in hemodialysis patients. Dialysis-Transplantation -
ME Suliman, AR Qureshi, P Barany, P Stenvinkel, CD … - Kidney International-, 2000 - pt.wkhealth.com
... and progressive occlusive vascular disease is high in chronic uremic patients and
accounts for more than 40% of the deaths in dialysis patients [4]. The ...

Interleukin-6 predicts hypoalbuminemia, hypocholesterolemia, and mortality in hemodialysis patients. -
RM Bologa, DM Levine, TS Parker, JS Cheigh, D … - Am J Kidney Dis, 1998 - ncbi.nlm.nih.gov
Am J Kidney Dis. 1998 Jul;32(1):107-14. Interleukin-6 predicts hypoalbuminemia,
hypocholesterolemia, and mortality in hemodialysis patients. ...

Source: Google Scholar

Study Questions Impact of Hemoglobin Variations on Mortality in Dialysis Patients

For patients with dialysis-related anemia, the risk of death is increased when hemoglobin levels remain persistently low over a period several months—not necessarily when they fluctuate over time, according to a study in the January Clinical Journal of the American Society of Nephrology.

"Our results show that the effect of hemoglobin variability on mortality, beyond the absolute level of hemoglobin, may not confer much additional risk, after adjusting for other illnesses and hospitalizations," comments David T. Gilbertson, Ph.D., of the Minneapolis Medical Research Foundation, Minneapolis, Minn.

Dr. Gilbertson and colleagues used data on nearly 160,000 dialysis patients to analyze the effects of variations in hemoglobin level on the risk of death. Patterns of hemoglobin variability during the first six months of 2004 were analyzed and compared with mortality rates over the subsequent six months.

Hemoglobin is the oxygen-carrying compound in the blood. Anemia, or low hemoglobin levels, is one of the most frequent complications of kidney failure and is associated with an increased risk of death in dialysis patients. Treatment including erythropoietin and intravenous iron has been a major advance in the management of kidney failure-related anemia, yet low blood counts and variation in hemoglobin levels continue to be a problem for many dialysis patients.

In the study, patients who developed low hemoglobin levels during the monitoring period were at increased risk of death. This was true both for patients with temporary reductions in hemoglobin and those whose hemoglobin level was persistently low. This risk was considerably greater than any risk associated with fluctuations in hemoglobin levels.

On further analysis, the key risk factor seemed to be the amount of time spent with a low hemoglobin level—not the hemoglobin variations themselves. Patients who spent three months or longer with low hemoglobin levels had the highest mortality rates.

"A number of research groups have shown that variability of hemoglobin levels is very common in patients receiving dialysis for end-stage renal disease," says Dr. Gilbertson. "Low hemoglobin levels, which are an indication of anemia, have been shown to be associated with poor outcomes. It is relatively unknown whether fluctuations in hemoglobin levels add additional risk." If so, then more intensive treatment might be needed to keep hemoglobin levels within a relatively narrow range.

"Our results suggest that fluctuations in hemoglobin levels probably do not add much to the mortality risk for patients with dialysis-related anemia," Dr. Gilbertson concludes. "Low hemoglobin levels show significantly greater associations with increased risk of death than fluctuations in hemoglobin levels." More research will be needed to evaluate the causes of variations in hemoglobin levels, including what proportion of the variability is under the control of doctors and dialysis centers.

This study was supported by a research contract from Amgen, Inc., Thousand Oaks, Calif. The contract provides for the investigators of the Minneapolis Medical Research Foundation to have the final determination of the content of this publication. The following study authors have received consulting fees from Amgen: David T. Gilbertson, Robert N. Foley, and Allan J. Collins. Study author Brian D. Bradbury works in the Department of Epidemiology at Amgen, Inc.

The study entitled, "Hemoglobin Level Variability: Associations with Mortality" is available online at http://cjasn.asnjournals.org and in print in the January issue of the Clinical Journal of the American Society of Nephrology (CJASN).

The ASN is a not-for-profit organization of 10,500 physicians and scientists dedicated to the study of nephrology and committed to providing a forum for the promulgation of information regarding the latest research and clinical findings on kidney diseases.
 
 
 
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