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Recent News and Articles on the Keywords: metabolic syndrome + blood pressure + link  Related to the article below (Last Update: 5/13/2008)

Obesity-Related Inflammation Boosts Heart Risks
Washington Post, United States - May 6, 2008
Metabolic syndrome is a collection of risk factors -- obesity, high blood pressure, elevated blood glucose levels, excess abdominal fat, and abnormal ...
Less than 6 hours sleep 'increases heart risk'
Telegraph.co.uk, United Kingdom - May 1, 2008
A lack of sleep was found to raise the risk of metabolic syndrome, a set of symptoms including high cholesterol, increased blood pressure, a large waist ...
Sleeping less ?doubles risk of heart disease? The News - International
all 26 news articles »
Less Sleep Means More Heart Risk
HeartZine, UK - May 8, 2008
It can also increase the risk of metabolic syndrome, a combination of symptoms that include high cholesterol, increased blood pressure, a large waist ...
Update in Sleep and Control of Ventilation 2007
RedOrbit, TX - May 2, 2008
Metabolic syndrome was identified if threshold levels were exceeded in three of five areas: waist circumference, blood pressure, triglyceride level, ...
Don?t Sleep too Much or too Little
Ivanhoe, FL - Apr 29, 2008
The link between metabolic syndrome and sleep duration was strongest in the short sleepers. Overall, they were nearly twice as likely as normal sleepers to ...

Nigerian Tribune
Your Health
Nigerian Tribune, Nigeria - Apr 23, 2008
This can cause high blood pressure, which can damage the carotid arteries on each side of the neck. The carotid arteries carry oxygen to the brain. ...

Southwest News-Herald
Your Daily Dose of DGAs
Southwest News-Herald, IL - Apr 14, 2008
Metabolic syndrome is a condition that occurs among people who have at least three of the following health risks: abdominal obesity, poor control of blood ...
May Conference to address impact of obesity, nutrition on health
Media Newswire (press release), NY - Apr 30, 2008
... on bone breaks and metabolic syndrome, a session on the relationship between dietary variety and obesity and a presentation exploring the link between ...
Morten Bryhn, MD, Ph.D., Presents "DHA Omega-3 and Type 2 Diabetes ...
NPIcenter (press release), Canada - Apr 30, 2008
This has led to a marked increase in metabolic syndrome, a clustering of risk factors for cardiovascular disease characterized by elevated blood pressure, ...
Cecil Chandler speaks about having diabetes and effects it's had ...
Florence Morning News, SC - Apr 24, 2008
This whole metabolic syndrome that occurs in people that are overweight and obese includes hypertension, hyperlymphodemic, which are the high fats and ...
Source: Google News

Prevalence of the Metabolic Syndrome Among US Adults Findings From the Third National Health and … -
ES Ford, WH Giles, WH Dietz - JAMA, 2002 - Am Med Assoc
... The Farnesoid X Receptor: A Molecular Link Between Bile ... Several Others Relate to
Factors of Metabolic Syndrome in the Family Blood Pressure Program Kraja ...

… of Metabolic Syndrome Report of the National Heart, Lung, and Blood Institute/American Heart … -
SM Grundy, HB Brewer, JI Cleeman, SC Smith, C … - Circulation, 2004 - Am Heart Assoc
... favored inclusion of elevated blood pressure as one ... It strongly associates with other
metabolic risk factors ... account for the term insulin resistance syndrome. ...

The metabolic syndrome?a new worldwide definition -
KGMM Alberti, P Zimmet, J Shaw - The Lancet, 2005 - Elsevier
... International Diabetes Federation: metabolic syndrome definition Central ... lipid
abnormality Raised blood pressure Systolic 130 mm ... to define presence of syndrome. ...

Hyperleptinaemia: the Missing Link in the Metabolic Syndrome? -
M de Courten, P Zimmet, A Hodge, V Collins, M … - Diabetic Medicine, 1997 - doi.wiley.com
... Hyperleptinaemia: the Missing Link in ... is a central component of the Metabolic Syndrome
independent of ... and Treat- ment of High Blood Pressure: 39 systolic blood ...

… Plasma Cortisol Concentrations: A Link between Low Birth Weight and the Insulin Resistance Syndrome … -
DIW Phillips, DJP Barker, CHD Fall, JR Seckl, CB … - Journal of Clinical Endocrinology & Metabolism, 1998 - Endocrine Soc
... alterations in HPAA activity could explain the link between reduced ... in the impairment
of lipid metabolism observed in the metabolic syndrome. ... Blood Pressure. ...

The Metabolic Syndrome and Total and Cardiovascular Disease Mortality in Middle-aged Men -
HM Lakka, DE Laaksonen, TA Lakka, LK Niskanen, E … - JAMA, 2002 - Am Med Assoc
... Featured Link, ? E-mail Alerts, ... Assessment of Components of the Metabolic Syndrome.
Blood pressure was measured with a random-zero mercury sphygmomanometer. ...

… events by optimal control of blood pressure and lipids in patients with the metabolic syndrome -
ND Wong, JR Pio, SS Franklin, GJ L?Italien, TV … - The American Journal of Cardiology, 2003 - Elsevier
... 9149(03)00392-8 How to Cite or Link Using DOI ... coronary events by optimal control
of blood pressure and lipids in patients with the metabolic syndrome *1. ...

… and Validation of Recently Suggested Definitions of the Metabolic Syndrome in a Prospective Cohort … -
DE Laaksonen, HM Lakka, LK Niskanen, GA Kaplan, JT … - American Journal of Epidemiology, 2002 - pt.wkhealth.com
... Link]. 3. Bouchard C. Genetics and the metabolic syndrome. ... not with the insulin
resistance syndrome: the Hoorn ... evaluation, and treatment of high blood pressure. ...

… Management of the Metabolic Syndrome An American Heart Association/National Heart, Lung, and Blood … -
SM Grundy, JI Cleeman, SR Daniels, KA Donato, RH … - Circulation, 2005 - Am Heart Assoc
... have also been proposed to link insulin resistance ... emphasis in people with the metabolic
syndrome; the goals here are to reduce blood pressure as much as ...

Hyperinsulinaemia: the key feature of a cardiovascular and metabolic syndrome -
E Ferrannini, SM Haffner, BD Mitchell, MP Stern - Diabetologia, 1991 - Springer
... resistance with the physiological and metabolic changes found ... a primary insulin
resistance syndrome (Fig. ... hyper- glycaemia or high blood pressure) dominate the ...

Source: Google Scholar

Linking Players In Blood Pressure Control To Metabolic Syndrome
A new study elucidates the connection between an enzyme involved in blood pressure control and symptoms of the metabolic syndrome. The researchers report in the December issue of Cell Metabolism, a publication of Cell Press, that mice lacking the enzyme known as renin are lean and resistant to gaining weight on a high-fat diet, even though they continue to eat just as much and don't exercise more.

The findings suggest that renin-blocking drugs designed for treating high blood pressure might also improve obesity and insulin resistance, according to the researchers. Renin plays an important rate-limiting role in the production of a hormone called angiotensin II (Ang II) that increases blood pressure by constricting blood vessels.

"An overactive renin-angiotensin system has also been associated with obesity and the metabolic syndrome," said Nobuyuki Takahashi of The University of North Carolina at Chapel Hill. "Now we've gained new insight into the mechanism responsible."
The metabolic syndrome is characterized by central obesity, hypertension, abnormally high blood lipid levels, and impaired glucose tolerance, the researchers explained. It also increases the risk of heart disease and type 2 diabetes. While most theories to explain the condition have focused on primary defects of insulin action, the renin-angiotensin system has also been implicated.

Clinical trials have shown that drugs that block other parts of the renin-angiotensin system improve insulin sensitivity and decrease the incidence of type 2 diabetes. Studies have also revealed that mice lacking angiotensinogen, the substrate that renin acts on, are lean and resistant to diet-induced obesity.

In the current study, the researchers generated mice with a predisposition for obesity that were also deficient for renin. They found that the renin-less mice were lean, resistant to diet-induced obesity, and more insulin sensitive than normal mice.

"This metabolically favorable state results partly from an increased metabolic rate and partly from gastrointestinal loss of dietary fat, but not from increased physical activity or decreased food intake," they said. The metabolic effects were explained almost entirely by a lack of Ang II in the absence of renin. Renin's other effects on metabolism were minimal.

"Our findings are particularly relevant since they suggest that renin inhibitors recently approved or under development for the treatment of hypertension are likely to have favorable effects on obesity, insulin sensitivity, and their associated metabolic and cardiovascular consequences," the researchers said.

The researchers include Nobuyuki Takahashi, Feng Li, Kunjie Hua, Jianbei Deng, Chih-Hong Wang, Hyung-Suk Kim, and Joyce B. Harp, of The University of North Carolina at Chapel Hill, in Chapel Hill, NC, USA; Robert R. Bowers, and Timothy J. Bartness, of the Center for Behavioral Neuroscience, Georgia State University, Atlanta, GA, USA.

Source:
Cathleen Genova
Cell Press
 
 
 
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