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Recent News and Articles on the Keywords: dose may + epinephrine dose + anaphylaxis  Related to the article below (Last Update: 5/5/2008)

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Source: Google News

Anaphylaxis: A review of causes and mechanisms -
SF Kemp, RF Lockey - The Journal of Allergy and Clinical Immunology, 2002 - Elsevier
... Cimetidine (4 mg/kg) alternatively may be administered to ... d. For bronchospasm resistant
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First-aid treatment of anaphylaxis to food: Focus on epinephrine -
FER Simons - The Journal of Allergy and Clinical Immunology, 2004 - Elsevier
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EpiPen Jr versus EpiPen in young children weighing 15 to 30 kg at risk for anaphylaxis -
FER Simons, X Gu, NA Silver, KJ Simons - The Journal of Allergy and Clinical Immunology, 2002 - Elsevier
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… intramuscular injection of epinephrine: Dose equivalence for potential treatment of anaphylaxis -
MM Rawas-Qalaji, FER Simons, KJ Simons - The Journal of Allergy and Clinical Immunology, 2006 - Elsevier
... by the magnitude of the epinephrine dose administered. ... of the 10-mg sublingual tablet
may have resulted in ... similar to those obtained after epinephrine 0.34 mg ...

Proposed use of adrenaline (epinephrine) in anaphylaxis and related conditions: a study of senior … -
LL Gompels, C Bethune, SL Johnston, MM Gompels - Postgraduate Medical Journal, 2002 - pt.wkhealth.com
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A second dose of epinephrine for anaphylaxis: How often needed and how to carry -
JM Kelso - The Journal of Allergy and Clinical Immunology, 2006 - Elsevier
... to require a second dose, the route of administration of epinephrine is not ... The
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A Retrospective Study of Epinephrine Administration for Anaphylaxis: How Many Doses Are Needed? -
P Korenblat, MJ Lundie, RE Dankner, JH Day - Allergy and Asthma Proceedings, 1999 - ingentaconnect.com
... Patients at risk for anaphylaxis and their caregivers need to recognize that more
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Use of Epinephrine for Anaphylaxis by Emergency Medical Technicians in a Wilderness Setting -
JE Fortenberry, J Laine, M Shalit - Annals of Emergency Medicine, 1995 - Elsevier
... the patients received a second epinephrine dose in the ... Bs in SKCNP to use epinephrine
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… Inhalations Be Substituted for Epinephrine Injection in Children at Risk for Systemic Anaphylaxis? -
FER Simons, X Gu, LM Johnston, KJ Simons - Pediatrics, 2000 - Am Acad Pediatrics
... as exercise or cold exposure may be inadvertently ... to administer more than one
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Anaphylaxis: can we tell who is at risk of a fatal reaction? -
R Pumphrey - Current Opinion in Allergy and Clinical Immunology, 2004 - co-allergy.com
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Source: Google Scholar

Two epinephrine doses may be needed for anaphylaxis

Last Updated: 2007-12-05 14:18:44 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Some patients who are at risk for a severe allergic reaction caused by a food allergy will require two doses of epinephrine, rather than just one, according to the findings of a new study. Researchers therefore recommend that allergic patients carry two doses of epinephrine.

Dr. Eyal Oren of Massachusetts General Hospital in Boston and colleagues reviewed the records of patients seen at the hospital's emergency department for food-induced anaphylaxis, a severe, life-threatening allergic reaction that requires immediate treatment. It is characterized by swelling of the airways that can block breathing and may also include a dramatic drop in blood pressure.

The investigators reviewed medical records of 39 patients who sought treatment for severe allergic reactions to food at the hospital's emergency department over the course of 1 year. Nineteen had anaphylaxis.

Twelve of the patients were given at least one dose of epinephrine, while three, or 16 percent, received two doses. The patients given two doses were allergic to peanuts or tree nuts, and two of the three experienced a drop in blood pressure.

"These results suggest that the use of multiple doses of epinephrine in the management of food-induced anaphylaxis is not a rare occurrence," they write in the current issue of the Annals of Allergy, Asthma and Immunology.

Recent recommendations have called for allergic individuals to carry two doses of epinephrine rather than just one. These findings suggest that those with food allergies will also benefit from doing so, Oren and his team note.

Given the small size of the study and the fact that patients who were not seen in the emergency room for treatment weren't included, more research is needed to confirm the findings, the researchers say.

Nevertheless, they conclude, the findings suggest that patients "at risk for food-induced anaphylaxis should carry at least two doses of self-injectable epinephrine."

SOURCE: Annals of Allergy, Asthma and Immunology, November 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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