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Recent News and Articles on the Keywords: stem cell + stem cells + new  Related to the article below (Last Update: 7/8/2008)


CitizenLink
Stem cell discovery could ease ethical fears
Scotsman, United Kingdom -
But to date, stem cells have been obtained from five-day-old embryos in a process which breaks the embryo apart. The new development suggests stem cells can ...
End the stem cell ban Detroit Free Press
Michigan stem cell research proposal advances The Associated Press
Michigan Likely to Vote on Forcing Funding of Embryonic Stem Cell ... LifeNews.com
The Canadian Press - Detroit Free Press
all 294 news articles »
International Stem Cell Corporation Announces Collaboration with ...
FOXBusiness -
OCEANSIDE, Calif., Jul 08, 2008 (BUSINESS WIRE) ----International Stem Cell Corporation (OTCBB: ISCO) announced today a new collaboration with leading stem ...OTC:ISCO

WWL
Dr. breaks new ground by using stem cells on damaged hearts
WWL, LA -
A local doctor is doing the only research of its kind with stem cells that could prove to be life saving for people with cardiovascular disease. ...
Opexa's Phase IIb Study of Tovaxin(R) Receives Positive Review ...
FOXBusiness -
The Company is focused on autologous cellular therapy applications of its proprietary T-cell and stem cell therapies. The Company's lead product is Tovaxin, ...OPXA
Stem Cell granted new Prolactin patents
Trading Markets (press release), CA -
Jul 08, 2008 (Datamonitor via COMTEX) -- SCTPF | Quote | Chart | News | PowerRating -- Stem Cell Therapeutics has received two new Prolactin corresponding ...CVE:SSS - OTC:CMTX
Leading Plastic Surgeons Reveal Revolution in Stem Cell Research ...
PR Web (press release), WA -
"Stem cells are in the fat and have always been in the fat. The reparative results are seen in weeks and seem to improve with time," said Ellenbogen. ...
BrainStorm Cell Therapeutics and Rutgers University Study Shows ...
FOXBusiness -
NEW YORK & PETACH TIKVAH, Israel, Jul 07, 2008 (BUSINESS WIRE) ----BrainStorm Cell Therapeutics Inc. (OTCBB:BCLI), a leading developer of adult stem cell ...CTIC
Ky. Girl Heads To China For Stem Cell Treatment
Kentucky Post, KY -
Five-year-old Haley Goranflo has Batton's Disease, which can only be treated with stem cells. Haley and her mother were planning on taking the long trip two ...
KY Girl Headed To China For Treatment WYMT
Flight with local family trying to transport daughter to China has ... WHAS 11.com (subscription)
Ky. Girl Headed To China For Treatment WYMT
all 8 news articles »
UPI NewsTrack Health and Science News
United Press International -
LOUIS, July 8 (UPI) -- US researchers have shown mouse embryonic stem cells can build the heart, thereby moving science closer to heart disease treatments ...
Novel high-throughput automated stem cell culture & screening system
PharmaLive.com (press release), PA -
KINGSTON, England, July 8, 2008-A novel high-throughput automated stem cell culture and screening system is described in a new technical data sheet ...
Source: Google News

CNS stem cells express a new class of intermediate filament protein -
U Lendahl, LB Zimmerman, RD McKay? - Cell, 1990 - neuron.org
... Full Text] [PDF] A New Role for Glia: Generation of Neurons! Ben A Barres 1999,
97:6:667-670 [Full Text] [PDF] Identification of a Neural Stem Cell in the ...

[CITATION] Bone marrow stem cells regenerate infarcted myocardium -
D Orlic, J Kajstura, S Chimenti, DM Bodine, A Leri … - Pediatric Transplantation, 2003 - Blackwell Synergy
... At 27 days after induction of an infarct by coronary artery occlusion, the mobilized
stem cells regenerated a new band of myocardium that occupied 76% of the ...

Multilineage Potential of Adult Human Mesenchymal Stem Cells -
MF Pittenger, AM Mackay, SC Beck, RK Jaiswal, R … - Science, 1999 - sciencemag.org
... to differentiate into multiple cell types in vitro, establishing their stem cell
nature ... of multiple tissue types and the potential of new therapeutic approaches ...

Adult Stem Cells for Tissue Repair--A New Therapeutic Concept? -
M Korbling, Z Estrov - New England Journal of Medicine, 2003 - content.nejm.org
... Next Next. Adult Stem Cells for Tissue Repair ? A New Therapeutic Concept? ... Eradication
of Leukemia Stem Cells as a New Goal of Therapy in Leukemia. Clin. ...

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor … -
J Nichols, B Zevnik, K Anastassiadis, H Niwa, D … - Developmental Cell, 2004 - cell.com
... Nanog: A New Recruit to the Embryonic Stem Cell Orchestra Fatima Cavaleri and Hans
R. Sch?ler Cell, 2003, 113:5:551-552 [Summary] [Full Text] [PDF]; ...
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cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells -
GR Martin - Proceedings of the National Academy of Sciences of the …, 1981 - JSTOR
... here, as well as the one re- cently reported by Evans and Kaufman (12), also has
immediate practical value for the isolation of new pluripotent stem cell lines ...

[PDF] Stem cells, cancer, and cancer stem cells -
T Reya, SJ Morrison, MF Clarke, IL Weissman? - Nature, 2001 - microarray.princeton.edu
... and clinical applications havebeen covered in earli- er reviews, here we discuss
emerging evidence that stem cell biology could provide new insights into ...
-

Embryonic Stem Cell Lines Derived from Human Blastocysts -
JA Thomson, J Itskovitz-Eldor, SS Shapiro, MA … - Science, 1998 - sciencemag.org
... Keller, G. (2005). Embryonic stem cell differentiation: emergence of a new
era in biology and medicine. Genes & Dev. 19: 1129-1155 ...

Mammalian Neural Stem Cells -
FH Gage - Science, 2000 - sciencemag.org
... stem cell will divide symmetrically or asymmetrically, differentiate into a neuron
or a glial cell, become quiescent, or die? What are the functions of the new ...

Stem Cells A New Lease on Life -
E Fuchs, JA Segre - Cell, 2000 - Elsevier
... As new clues are obtained from additional developmental and cell culture ... to provide
pivotal groundwork for future clinical applications of stem cell technology ...

Source: Google Scholar

New Treatment Of Disorders Of The Cornea Employing Adult Stem Cell Growth

A new method of adult stem cell growth, designed in the Area of Cellular Therapy of the University Clinic (University of Navarra), has demonstrated its efficacy for its capacity to grow cornea stem cells. So Ana Fernandez Hortelano, ophthalmologist at the Hospital demonstrated on applying the growth technique in treating diseases of the cornea, using stem cells, in 70 test animals (rabbits). The aim of the procedure was to regain the damaged epithelium and thus restore transparency to the cornea.

The thesis, defended by doctor Fernández Hortelano at the Faculty of Medicine of the University of Navarra, proves the therapeutic efficiency of using corneal stem cells in patients with pathologies of the cornea, such as caustications or ocular herpes, by using stem cells from a healthy contralateral eye. The technique is being currently applied to patients with satisfactory results.
The research has two essential parts. On the one hand, it describes the design of a new method of cell growth and, on the other, explains the clinical application of the procedure.

The research undertaken by the ophthalmologist has shown that, from a small biopsy sample, the new technique enables the growth of a number of stem cells sufficient for the treatment to be effective. The cell sample is taken from the limb of the healthy eye -- the ocular structure responsible for the transparency of the cornea.

The importance of this growth method lies in the fact that it enables the characterisation of the cells obtained, i.e. determining the quantity and viability of the units to be used.

The method developed combines culture on a plastic chip with that of pne on an amniotic membrane. The novelty of the technique focuses on the first stage -- where the plastic chip is used. The fragment of tissue obtained from the healthy eye divides into smaller fractions which are grown on the chip. Thus a greater number of halos of stem cells are obtained (as many as the fragments of tissue). A sample of the cells obtained are then sent the Anatomic Pathology laboratory where the viability and quality of the cell units are verified.

The cells are transferred to the amniotic membrane growth culture, one that is highly suitable when dealing with stem cells that are to be transplanted for ocular regeneration treatment.

Once in the amniotic membrane, the stem cells expand in a homogeneous manner, enabling a better cell identification in order to select the most suitable units for the treatment. This method reveals the cell population that we are implanting in the eye and verifies the quality and quantity of the cells transplanted.

The second part of the research involves the clinical application of the adult stem cells transplanted in rabbits, which previously have had an epithelial corneal lesion induced, causing loss of corneal transparency. This is a pathology that does not respond to a corneal transplant nor to other conventional treatment.

The procedure used by Dr Fernández Hortelano involved obtaining this type of cell -- corneal stem cells -- by means of a biopsy of cells from the healthy eye of the rabbit. This is a small sample of cells -- 3 by 4 mm -- and so the contrateral eye is not in danger. It is then necessary to grow the samples in order to obtain greater numbers of cells, an expansion achieved by transferring the culture to the amniotic membrane.
The adult stem cells obtained are implanted in the damaged eye and the limb is regenerated, leading to the recovery of the corneal epithelium and the transparency of the cornea. The results to date achieved amongst the group of rabbits, with induced limbic insufficiency and which then had a transplant of adult stem cells, showed recovery of the corneal epithelium in 60% of the treated animals. The corneal epithelium is the layer that is damaged with limbic insufficiency, a problem which, in the long term, results in opacity of the cornea.

Source: Irati Kortabitarte
Elhuyar Fundazioa
 
 
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