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Recent News and Articles on the Keywords: lower serotonin + rotating shift + serotonin  Related to the article below (Last Update: 5/12/2008)

Study: The less sleep you get, the more problems you encounter
St. Louis Post-Dispatch,  United States - Apr 13, 2008
And people who do rotating-shift work have lower levels of the hormone serotonin, low levels of which are associated with anxiety and depression. ...
Source: Google News

EEG synchronization following application of serotonin to area postrema -
JD BRONZINO, PJ MORGANE, WC STERN - American Journal of Physiology - Am Physiological Soc
... The lower half-amplitude frequency setting was 0.25 Hz ... acetylcholine, norepinephrine,
Xylocaine, and serotonin were applied in a rotating sequence (ie ...

… of protonated excited-state forms of 5-hydroxytryptamine (serotonin) and related indoles. -
RF Chen - Proceedings of the National Academy of Sciences of the …, 1968 - JSTOR
... With the rotating shutter in place, the ultraviolet band ... In the case of serotonin
and related indoles, if ... state, one would expect a relatively lower yield of ...

Influence of synaptic serotonin level on [18F] altanserin binding to 5HT2 receptors in man -
R Larisch, A Klimke, K Hamacher, U Henning, S … - Behavioural Brain Research, 2003 - Elsevier
... none of them received medication influencing serotonin receptors or ... The remainder
was given at lower speed over the ... the emission scans using a rotating 68 Ge ...

Visualization of modulatory effects of serotonin in the silkmoth antennal lobe -
ES Hill, K Okada, R Kanzaki - Journal of Experimental Biology, 2003 - jeb.biologists.org
... the time course of the effects of serotonin, we used programs to rotate and shift ...
Application of a lower concentration of serotonin (10 -5 mol l ...

Power spectrum analysis of EEG synchronization following application of serotonin to area postrema -
JD Bronzino, J Brusseau, PJ Morgane, WC Stern - Annals of Biomedical Engineering, 1972 - Springer
... and sero- tonin were applied in a rotating sequence (ie ... in relative power densities
at lower frequencies, and ... that the topical application of serotonin to the ...

Functional bowel disorders in rotating shift nurses may be related to sleep disturbances. -
WZ Lu, KA Gwee, KY Ho - European Journal of Gastroenterology & Hepatology, 2006 - eurojgh.com
... of this condition is very low in this ... our study showed that FBD in rotating shift
nurses may ... irritable bowel syndrome; melatonin; night shift; serotonin; sleep. ...

Ethanol-Related Behaviors in Serotonin Transporter Knockout Mice -
JM Boyce-Rustay, LM Wiedholz, RA Millstein, J … - Alcoholism: Clinical and Experimental Research, 2006 - Blackwell Synergy
... important role for the brain serotonin [5-hydroxytryptamine ... 2 revolutions per minute
(rpm)] rotating rod, which ... mice showed a significantly lower latency than ...

Serotonin and serotonin transporter gene variant in rotating shift workers. -
S SOOKOIAN, C GEMMA, TF Gianotti, A Burgue?o, A … - Sleep(New York, NY), 2007 - pubmedcentral.nih.gov
... Platelet 5-HT and 5-HIM contents were significantly lower in rotating shift ... Serotonin
and serotonin transporter gene variant in rotating shift workers. ...

… Provides Specific Optical and NMR Signatures for Serotonin at Intravesicular Concentrations -
S Nag, J Balaji, PK Madhu, S Maiti - Biophysical Journal, 2008 - Biophysical Soc
... is evident in the two dimensional NMR Rotating Frame Overhauser ... the osmolality of
a high concentration serotonin solution is substantially lower than that ...
-

… Melatonin Synthesis: Light and Cyclic AMP Control Abundance of Serotonin N-Acetyltransferase Protein … -
M Zatz, JA Gastel, JR Heath III, DC Klein - Journal of Neurochemistry, 2000 - pt.wkhealth.com
... Piscataway, NJ, USA) at 4?C (rotating) for 1 ... an LR 12:12 cycle (upper) and in RR
(lower). ... of the pineal melatonin rhythm: regulation of serotonin N-acetylation ...

Source: Google Scholar

Rotating shift workers have lower levels of serotonin

WESTCHESTER, Ill. -- People who work rotating shifts have significantly lower levels of serotonin, a hormone and neurotransmitter in the central nervous system believed to play an important role in the regulation of sleep, according to a study published in the August 1st issue of the journal SLEEP.

The study, authored by Carlos J. Pirola, PhD, of the Universidad de Buenos Aires, Argentina, focused on 683 men of self-reported European ancestry, in which 437 day workers were compared with 246 rotating shift workers. Day and night work periods started at 6 a.m. and 6 p.m. respectively. None of the subjects interchanged their job schedule.

The results showed that serotonin content differed greatly between day workers and rotating shift workers, with levels of serotonin significantly higher in day workers.

“These findings may be important not only to understand the mechanisms related to the circadian rhythm desynchronization imposed by the rotating shift work regime, but also to target truly effective therapeutic strategies that may ameliorate the associated comorbidities and behavioral problems in rotating shift workers,” said Pirola.

In addition to sleep problems, low levels of serotonin are also associated with other conditions such as anger, depression and anxiety.

Shift work sleep disorder is a circadian rhythm sleep disorder that occurs due to a work schedule that takes place during the normal sleep period. This schedule requires you to work when your body wants to sleep. Then you have to try to sleep when your body expects to be awake. The timing of when you sleep and wake is much different than what your internal body clock expects.

This sleep problem causes you to have trouble sleeping or to be severely tired. It is most often reported due to the night and early-morning shifts. These workers typically sleep one to four hours less than average. They also feel that the quality of their sleep is very poor. They do not feel refreshed when they wake up. This can hinder their performance at work. It can also make them less alert. This can put them at risk of an injury on the job.

Sleep problems from shift work affect male and female workers of all age groups. Those who have unusual work hours are most likely to have it. Estimates are that two to five percent of the general population is affected.

Those who suspect they might be suffering from shift work sleep disorder, or another sleep problem, are urged to consult with their primary care doctor or a sleep specialist.

SLEEP is the official journal of the Associated Professional Sleep Societies, LLC, a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society.

SleepEducation.com, a Web site maintained by the AASM, provides information about the various sleep disorders that exist, the forms of treatment available, recent news on the topic of sleep, sleep studies that have been conducted and a listing of sleep facilities.

For a copy of this article, entitled, “Serotonin and Serotonin Transporter Gene Variant in Rotating Shift Workers”, or to arrange an interview with an AASM spokesperson regarding this study, please contact Jim Arcuri, public relations coordinator, at (708)492-0930, ext. 9317, or jarcuri@aasmnet.org.
 
 
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