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Recent News and Articles on the Keywords: etoricoxib and + arthritis + etoricoxib  Related to the article below (Last Update: 5/5/2008)

Need to know - osteoarthritis
Pulse, UK - Apr 8, 2008
... treatment with an oral NSAID or cox-2 inhibitor, the first choice should either be a standard NSAID or a cox-2 inhibitor ? other than etoricoxib 60mg/d. ...
DUBLIN, Ireland--(BUSINESS WIRE)--
Ad-Hoc-News (Pressemitteilung), Germany - Apr 11, 2008
... targets the US$688mn NSAID market, with two other leading NSAID brands produced by Dr Reddy's, namely Nise (nimesulide) and Retoz (etoricoxib). ...
Source: Google News

A randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis -
AK Matsumoto, A Melian, DR Mandel, HH McIlwain, D … - J Rheumatol, 2002 - jrheum.com
... HARRIS H. McILWAIN, DAVID BORENSTEIN, PENG LIANG ZHAO, CHRISTOPHER R. LINES, BARRY
J. GERTZ, SEAN CURTIS, and the Etoricoxib Rheumatoid Arthritis Study Group. ...
-

Randomised double blind trial of etoricoxib and indometacin in treatment of acute gouty arthritis -
HR Schumacher Jr, JA Boice, DI Daikh, S … - BMJ: British Medical Journal, 2002 - pubmedcentral.nih.gov
... 2002 June 22; 324(7352): 1488?1492. Copyright ? 2002, BMJ. Randomised double blind
trial of etoricoxib and indometacin in treatment of acute gouty arthritis. ...

[CITATION] … randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis
E Collantes, SP Curtis, KW Lee, N Casas, T McCarthy … - BMC Fam Pract, 2002

… osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis … -
CP Cannon, SP Curtis, GA FitzGerald, H Krum, A … - The Lancet, 2006 - Elsevier
... with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis
in the Multinational Etoricoxib and Diclofenac Arthritis Long-term ...

[CITATION] … Etoricoxib Rheumatoid Arthritis Study Group: A randomized, controlled, clinical trial of etoricoxib …
AK Matsumoto, A Melian, DR Mandel, HH McIlwain, D … - J Rheumatol, 2002

Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit … -
D Riendeau, MD Percival, C Brideau, S Charleson, D … - Journal of Pharmacology and Experimental Therapeutics, 2001 - ASPET
... Etoricoxib was a potent inhibitor in models of carrageenan-induced paw edema (ID
50 ... induced pyresis (ID 50 = 0.88 mg/kg), and adjuvant-induced arthritis (ID 50 ...

Efficacy of cyclo-oxygenase-2 inhibition by etoricoxib and naproxen on the axial manifestations of … -
L Gossec, D van der Heijde, A Melian, DA Krupa, MK … - British Medical Journal, 2005 - ard.bmj.com
... scale. Keywords: ankylosing spondylitis; non-steroidal anti-inflammatory
drugs; efficacy; peripheral arthritis; etoricoxib. The group ...

The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy … -
RH Hunt, S Harper, DJ Watson, C Yu, H Quan, M Lee, … - American Journal of Gastroenterology, 2003 - Blackwell Synergy
... Fewer GI-related treatment discontinuations with etoricoxib compared with nonselective
cyclooxygenase inhibitors (NSAIDs). Arthritis Rheum 2001;44(suppl 9):S317 ...

[CITATION] … osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis …
CP Cannon, SP Curtis, GA FitzGerald, H Krum, A … - Lancet, 2006

… studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib -
RH Hunt, S Harper, P Callegari, C Yu, H Quan, J … - Alimentary Pharmacology & Therapeutics, 2003 - Blackwell Synergy
... of endoscopically detectable gastric/duodenal ulcers was determined in 742
osteoarthritis or rheumatoid arthritis patients receiving etoricoxib (120 mg once ...

Source: Google Scholar

Etoricoxib and naproxen effective for arthritis

Last Updated: 2007-07-30 16:46:47 -0400 (Reuters Health)

NEW YORK (Reuters Health) - The COX-2 inhibitor etoricoxib and the older agent naproxen are both safe and effective for the treatment of arthritis, according to a report in the Annals of the Rheumatic Diseases.

Dr. Sean P. Curtis, of Merck Research Laboratories, Rahway, New Jersey, and colleagues studied etoricoxib at 60 milligrams once-daily versus naproxen 500 milligrams twice-daily over a 138-week period in patients with arthritis at 80 clinical centers in 19 countries. Nearly 1,000 patients were included in the study.

Etoricoxib and naproxen were comparable in their ability to reduce pain throughout the entire study period, the report indicates.

Both treatments were generally well tolerated and the side effects seen with each were similar. Still, more naproxen-treated patients were likely to discontinue the drug due to side effects than patients in the etoricoxib group.

"Regardless of treatment group, the most common (side effects) in the three study periods overall were upper respiratory infection and (high blood pressure)," they report.

The investigators also note that the study was not designed to compare the risk of gastrointestinal or heart side effects with each drug.

SOURCE: Annals of the Rheumatic Diseases, July 2007.

 

Dietary carbs linked to vision loss

Last Updated: 2007-07-30 16:49:17 -0400 (Reuters Health)

NEW YORK (Reuters Health) - The carbohydrates present in a diet can influence the risk of age-related macular degeneration (AMD), the most common cause of vision loss in older adults, according to a report in the American Journal of Clinical Nutrition.

"AMD appears to share several carbohydrate-related mechanisms and risk factors with diabetes-related diseases, including (eye) and cardiovascular disease," write Dr. Allen Taylor, of Tufts University, Boston, and colleagues. "However, to date, only one small study has addressed this issue." To investigate further, the researchers conducted a study of 4,099 participants, aged 55 to 80 years, in the Age-Related Eye Disease Study. The team classified a total of 8,125 eyes into one of five AMD groups based on the severity of the disease and other factors. Regular consumption of a diet with a high-glycemic index - a diet containing carbs that quickly raise blood sugar levels -- significantly increased the risk of AMD relative to regular consumption of a diet with a low-glycemic index.The researchers calculate that 20 percent of AMD cases could have been prevented if subjects had consumed diets with a low-glycemic index.

SOURCE: American Journal of Clinical Nutrition, July 2007.

 

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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