Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California
blank

 

Recent News and Articles on the Keywords: huntingtons disease + huntington's disease + their  Related to the article below (Last Update: 5/5/2008)

You can help man battle cancer
GoErie.com, PA -
PAOs may cause brain ailments such as Alzheimers, Parkinsons and Huntingtons diseases. In heart-disease patients, PAOs stiffen cells, Robbins says, ...
Source: Google News

Targeted disruption of the Huntington?s disease gene results in embryonic lethality and behavioral … -
J Nasir, SB Floresco, JR O'Kusky, VM Diewert, JM … - Cell, 1995 - current-biology.com
... E. File, Colin L. Stewart and Roger J. Morris Current Biology, 2000, 10:2:68-75
[Summary] [Full Text] [PDF] Huntington's Disease: Their loss is our gain? ...

Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease -
A Yamamoto, JJ Lucas, R Hen - Cell, 2000 - Elsevier
... and ME Figueiredo-Pereira, Ubiquitin, cellular inclusions and their role in ... Altherr
et al., Structure and expression of the Huntington's disease gene evidence ...

… prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease -
NR Swerdlow, J Paulsen, DL Braff, N Butters, MA … - British Medical Journal, 1995 - jnnp.bmj.com
... Even with stimuli that elicit maximal PPI in normal subjects, patients with
Huntington's disease exhibit little or no PPI, and their pattern of startle gating ...

Expanded polyglutamine in the Machado?Joseph disease protein induces cell death in vitro and in vivo -
H Ikeda, M Yamaguchi, S Sugai, Y Aze, S Narumiya, … - Nature Genetics, 1996 - nature.com
... as a pathological epitope in Huntington's disease and four ... The precursor of Alzheimer's
disease amyloid A4 protein ... structure of proteins from their amino acid ...

Cellular localization of the Huntington's disease protein and discrimination of the normal and … -
Y Trottier, D Devys, G Imbert, F Saudou, I An, Y … - Nature Genetics, 1995 - nature.com
... T., Suzuki, M. & Finch, JT Glutamine repeats as polar zippers: their possible role
in ... Characterization and localization of the Huntington disease gene product. ...

… Pathogenesis Emergence of Unifying Mechanisms for Huntington's Disease and Related Disorders -
CA Ross - Neuron, 2002 - Elsevier
... the first to be discovered; Huntington's disease (HD), perhaps ... each likely to have
their own additional ... diseases, such as Alzheimer's disease and Parkinson's ...

… of the neuropsychological deficits associated with early and advanced Huntington's disease -
N Butters, D Sax, K Montgomery, S Tarlow - Archives of Neurology, 1978 - Am Med Assoc
... Patients with "recently" diagnosed Huntington's Disease (RHD) were compared ... who have
had the disease three to ... focal deficits that stressed their memory deficits ...

Sp1 and TAFII130 Transcriptional Activity Disrupted in Early Huntington's Disease -
AW Dunah, H Jeong, A Griffin, YM Kim, DG Standaert … - Science, 2002 - sciencemag.org
... Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder
manifested by ... TAFII130 (TAFII130-M) are sufficient for their interaction with ...

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease … -
ME MacDonald, CM Ambrose, MP Duyao, RH Myers, C … - Cell, 1993 - actx.neuron.org
... New therapeutic approaches to Parkinson's disease Ann M Graybiel 1996, 6:4:368-371
[Summary] [Full Text] [PDF] Huntington's Disease: Their loss is our gain? ...

Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease. -
I Rouleau, DP Salmon, N Butters, C Kennedy, K … - Brain Cogn, 1992 - ncbi.nlm.nih.gov
... impairment has been reported in both Alzheimer's (DAT) and Huntington's (HD) disease,
there is ... DAT patients and were related to the severity of their dementia ...

Source: Google Scholar

Huntington's Disease Sufferers Need Focussed Management Of Sleep Symptoms In Their Treatment
Mice carrying the genetic mutation that causes Huntington's Disease (HD) showed marked improvements in alertness and their ability to learn after they were given drugs that put them to sleep.

Researchers at the University of Cambridge found that daily treatments of Alprazolam or chloral hydrate, two different sedative drugs, enabled them to develop a regular sleep pattern and improved their cognitive function -- their ability to understand and act on information.
According to the Cambridge neuroscientists conducting the research, HD mice have abnormal circadian rhythms; their daily sleeping and waking cycles are disrupted and irregular. Since sleep disruption contributes to problems with perception and learning in healthy people, the team wondered whether the circadian disruption and cognitive disturbances in HD mice were linked.

To test this, drugs were administered to regulate sleep patterns in the mice. The results, published today in the Journal of Neuroscience, show that both drugs caused a noticeable improvement in learning and Alprazolam also improved arousal. The study shows for the first time that treatments aimed at restoring normal sleep-wake activity could slow the cognitive decline that is such a devastating feature of the disease.

Dr. Jenny Morton, lead author of the study, said: "In the future, more attention should be paid to understanding sleep and circadian disturbance in HD. Management of these patterns may not only improve patients ability to think, learn and perform, but would also improve quality of life for both them and their carers."

The results have short-and long-term implications for treatment of HD and for the reversal of the disease's impairments. Recognising that sleep disturbance is a part of the disease means that clinicians should include focussed management of sleep symptoms in their treatment of HD patients.

Source: Genevieve Maul
University of Cambridge
 
 
 
Google
Web www.iconocast.com

Search inside Iconocast for the keyword you have in mind.

Iconocast has collected more than 50,000 articles and press releases on health and science.

These are current and most up to date press releases on the subject you are searching.

We collect current health and science press releases daily from more than 5000 research and health institutes. Here is an example : The elderberry way to perfect skin

We believe if you do search inside Iconocast, you will get better results than searching the web alone.

 
 
Continue News With: News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services.

 

Iconocast Home Page

Contact Iconocast

© 2003-07. ICONOCAST is a trademark of iconocast.com.