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Recent News and Articles on the Keywords: study reveals + male-factor infertility + infertility  Related to the article below (Last Update: 5/5/2008)

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Source: Google News

Role of sperm chromatin abnormalities and DNA damage in male infertility -
A Agarwal, TM Said - Human Reproduction Update, 2003 - ESHRE
... In a recent study conducted at the ... damage analysis usually reveals hidden abnormalities ...
including non- severe male factor infertility, unexplained infertility ...

… gonadotropin treatment: a prospective, randomized, crossover study during intrauterine insemination … -
A Arici, W Byrd, K Bradshaw, WH Kutteh, P … - Fertil Steril, 1994 - ncbi.nlm.nih.gov
... RESULTS: Twenty-nine couples completed the study and the analysis of 95 cycles revealed
that among the male factor infertility group, one pregnancy occurred ...

… leiomyomas reduce the efficacy of assisted reproduction cycles: results of a matched follow-up study -
DW Stovall - Human Reproduction, 1998 - ESHRE
... Our search of the literature revealed no data which ... assisted reproduction during
the study interval (36.8 ... of couples with male factor infertility undergoing IVF ...

PARTIAL OBSTRUCTION, NOT ANTISPERM ANTIBODIES, CAUSING INFERTILITY AFTER VASOVASOSTOMY -
DJ CARBONE, A SHAH, AJ THOMAS, A AGARWAL - The Journal of Urology, 1998 - Elsevier
... Our study reveals that in the persistently infertile patient ... Thus, the group in our
study with the ... in 49 men with pure male factor infertility and antisperm ...

Have sperm densities declined? A reanalysis of global trend data. -
SH Swan, EP Elkin, L Fenster - Environmental Health Perspectives, 1997 - pubmedcentral.nih.gov
... Moscato ML, Jouannet P, Czyglik F, David G. Study of a ... C. Data from men in greater
Seattle area reveals no downward ... The male factor in fertility and infertility ...

Evidence for decreasing quality of semen during past 50 years. -
E Carlsen, A Giwercman, N Keiding, NE Skakkebaek - BMJ: British Medical Journal, 1992 - pubmedcentral.nih.gov
... The male factor in fertility and infertility ... Circannual rhythm in human sperm count
revealed by serially ... A comparative study of zinc, copper, cadmium, and lead ...

… mapping of a patient who experienced failed fertilization at IVF reveals altered expression of at … -
KL Pixton, ED Deeks, FM Flesch, FLC Moseley, L … - Human Reproduction, 2004 - ESHRE
... the fertile donor proteome maps revealed excellent reproducibility ... may be useful
to study defects in ... ICSI and IVF in mild male factor infertility reported that ...

Study of DNA-methylation patterns at chromosome 15q11-q13 in children born after ICSI reveals no … -
M Manning, W Lissens, M Bonduelle, M Camus, M De … - Molecular Human Reproduction, 2000 - Oxford Univ Press
... ICSI procedure was performed because of male factor infertility in all ... In the present
study, the M-PCR of ... born after an ICSI procedure revealed a methylation ...

INCREASED INCIDENCE OF TESTICULAR CANCER IN MEN PRESENTING WITH INFERTILITY AND ABNORMAL SEMEN … -
JAYD RAMAN, CF NOBERT, M GOLDSTEIN - The Journal of Urology, 2005 - Elsevier
... In fact, subgroup analysis from that study revealed that men ... in men in our study
group, the ... during a routine physical examination for male factor infertility. ...

[PDF] Increased sperm nuclear DNA damage in normozoospermic infertile men: a prospective study -
RA Saleh, A Agarwal, DR Nelson, EA Nada, MH El- … - Fertil Steril, 2002 - clevelandclinic.org
... Conclusion(s): The results of this study indicate that ... sperm DNA damage analysis
may reveal a hidden ... Male-factor infertility plays a role in ap- proximately 50 ...

Source: Google Scholar

Study Reveals Surge In Male-Factor Infertility Technique
A national study reveals that the use of intracytoplasmic sperm injection or ICSI -- an assisted reproductive technology used to treat male-factor infertility -- has increased dramatically in the United States since 1995, while the proportion of patients receiving treatment for male-factor infertility has remained stable.

"Despite its added cost and uncertain efficacy and risk, the use of ICSI has been extended to include patients without documented male-factor infertility," said Dr. Tarun Jain, assistant professor of reproductive endocrinology and infertility at the University of Illinois at Chicago and lead author of the study that appears in the July 19 issue of the New England Journal of Medicine.
The research also compared the use of ICSI in states with and without mandated insurance coverage for infertility treatment.

States with mandated insurance coverage for infertility (Illinois, Massachusetts and Rhode Island) had a greater use of ICSI for reasons other than male-factor infertility when compared to states without mandated insurance coverage.

The researchers analyzed national data on assisted reproductive technology during a 10-year time span from 1995 to 2004. The study included all in vitro fertilization cycles involving fresh embryos from non-donor eggs in women younger than 43.

"The percentage of IVF cycles that used ICSI increased dramatically during the 10-year time span, from 11 percent to 57.5 percent, while the percentage of diagnosis for male-factor infertility remained steady," said Jain.

They also found that the number of fertility clinics and the number of fresh-embryo cycles has increased, as have pregnancy and live-birth rates.

Jain notes that some physicians may feel ICSI is appropriate for patients who have failed prior IVF cycles, for patients who have very few eggs available, or to overcome barriers to the normal fertilization process.

The largest study to compare traditional IVF with ICSI in patients without male-factor infertility found that patients who underwent ICSI had lower rates of implantation and pregnancy than patients who did not have ICSI, according to Jain.

There have been very few studies to evaluate the routine use of ICSI and the possibility of associated risks, such as genetic disorders and congenital anomalies.

"Further studies are needed to better understand the proper role of ICSI, and perhaps guidelines may be useful to determine what the best indications are for use of the technology in patients without male-factor infertility," said Jain.

Ruchi Gupta of Northwestern University is co-author of the study.
UIC ranks among the nation's top 50 universities in federal research funding and is Chicago's largest university with 25,000 students, 12,000 faculty and staff, 15 colleges and the state's major public medical center. A hallmark of the campus is the Great Cities Commitment, through which UIC faculty, students and staff engage with community, corporate, foundation and government partners in hundreds of programs to improve the quality of life in metropolitan areas around the world.

University of Illinois at Chicago
601 S. Morgan St. MC 288
Chicago, IL 60607-7113
United States
http://www.uic.edu/index.html
 
 
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