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Recent News and Articles on the Keywords: novel biomarkers + novel biomarker + research  Related to the article below (Last Update: 5/12/2008)

LineaGen Selects Affymetrix Technology to Discover Genes ...
WELT ONLINE, Germany -
LineaGen?s goal is to develop a diversified portfolio of novel biomarkers for the development of new diagnostic tests, and to strategically license its ...AFFX
SomaLogic and Otsuka Enter Into Research Collaboration
FOXBusiness - May 10, 2008
SomaLogic has generated novel aptamers that target over 500 human proteins. These aptamers have very high affinity and specificity. ...
Associate Director/ Director- Oncology Biomarker
Nature.com (subscription), UK - May 2, 2008
An important part of our success is the use of relevant and novel PD-biomarkers to help drive our decision making on which drugs to bring forwards and how ...
Senior Director, Oncology Biomarker Development Nature.com (subscription)
all 2 news articles »
Epigenomics AG Presents Data on Novel Prostate Cancer Biomarkers ...
Primenewswire (press release), CA - Apr 13, 2008
Biomarkers discovered by DMH were subsequently validated by real-time PCR technology in an independent sample set. A total of 26 novel biomarkers were ...FRA:ECX
Epigenomics AG Reports First Quarter 2008 Financial Results
FOXBusiness - May 6, 2008
As an interim result from Epigenomics' prostate cancer development program the company reported on the validation of 26 novel biomarkers in a tissue study. ...FRA:ECX
Burnham Institute for Medical Research Advances Biomarker Research ...
Earthtimes, UK - Apr 22, 2008
Aperio worked with Burnham researchers to develop advanced image analysis algorithms for Burnham?s novel dual or multicolor stainings in histology and ...
Senior Research Scientist, Intrinsic Bioprobes to Present at ...
PR-Inside.com (Pressemitteilung), Austria - Apr 22, 2008
This presentation will describe how this novel top-down proteomic approach can be applied to rediscover old biomarkers and increase their clinical utility. ...
AVEO Pharmaceuticals? Novel Triple VEGF Receptor Inhibitor Shows ...
Business Wire (press release), CA - Apr 14, 2008
?Results from Phase 1 research of our novel, oral triple VEGFR inhibitor have not only indicated highly selective, potent activity in some of the most ...
Astute Medical Gets $6.25M For Biomarker Research
socalTech.com, CA - May 1, 2008
Astute Medical is focused on developing novel diagnostic tests based an identification and validation of protein biomarkers. ...
Biomarkers allow doctors to match therapy to patient
Genetic Engineering News (press release), NY - Apr 13, 2008
Our work provides novel data on a potential biomarker for the monitoring of anti-angiogenic drug activity in cancer patients, as well as identifies a cell ...
Source: Google News

The Serum Concentration of Human Kallikrein 10 Represents a Novel Biomarker for Ovarian Cancer … -
LY Luo, D Katsaros, A Scorilas, S Fracchioli, R … - Cancer Research, 2003 - AACR
... 2003 American Association for Cancer Research Clinical Investigations. The Serum
Concentration of Human Kallikrein 10 Represents a Novel Biomarker for Ovarian ...

Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury. -
WK Han, V Bailly, R Abichandani, R Thadhani, JV … - Kidney International, 2002 - pt.wkhealth.com
... adhesion molecule containing a novel immunoglobulin domain ... WF, Porter GA: Urinary
biomarkers: Recommendations of the ... United states workshop for future research. ...

CCR7 and CXCR4 as Novel Biomarkers Predicting Axillary Lymph Node Metastasis in T1 Breast Cancer -
N Cabioglu, MS Yazici, B Arun, KR Broglio, GN … - Clinical Cancer Research, 2005 - AACR
... 11, 5686-5693, August 15, 2005 ? 2005 American Association for Cancer Research Human
Cancer Biology. CCR7 and CXCR4 as Novel Biomarkers Predicting Axillary ...

Development of a novel biomarker of free radical damage in reperfusion injury after cardiac arrest. -
S Basu, A Nozari, XL Liu, S Rubertsson, L Wiklund - FEBS Lett, 2000 - ncbi.nlm.nih.gov
... here to read Development of a novel biomarker of free ... plasma may be used as biomarkers
for quantification of ... Publication Types: Research Support, Non-US Gov't. ...

Human Kallikrein 8, a Novel Biomarker for Ovarian Carcinoma 1 -
T Kishi, L Grass, A Soosaipillai, A Scorilas, N … - Cancer Research, 2003 - AACR
... 63, 2771-2774, June 1, 2003] ? 2003 American Association for Cancer Research
Epidemiology and Prevention. Human Kallikrein 8, a Novel Biomarker for Ovarian ...

Diagnosis of Intra-amniotic Infection by Proteomic Profiling and Identification of Novel Biomarkers -
MG Gravett, MJ Novy, RG Rosenfeld, AP Reddy, T … - JAMA, 2004 - Am Med Assoc
... The objective of this study was to discover novel biomarkers for subclinical or ... and
Utilization Committee of the Oregon National Primate Research Center and ...

Novel Risk Factors for Systemic Atherosclerosis A Comparison of C-Reactive Protein, Fibrinogen, … -
PM Ridker, MJ Stampfer, N Rifai - JAMA, 2001 - Am Med Assoc
... based on the measurement of each novel marker in ... prospective evaluation of 11 plasma
biomarkers associated with ... measured using an in-house research-based assay ...

… Biomarker System from Ciphergen Biosystems: a novel proteomics platform for rapid biomarker … -
K Chapman - Biochem Soc Trans, 2002 - bst.portlandpress.com
... a novel proteomics platform for rapid biomarker discovery and validation. K. Chapman
1. Ciphergen Biosystems Ltd, Surrey Technology Centre, The Surrey Research ...
-

Identification of a novel serine protease-like gene, the expression of which is down-regulated … -
XL Liu - Cancer Research, 1996 - AACR
... 14 3371-3379, Copyright ? 1996 by American Association for Cancer Research. ... Serum
Concentration of Human Kallikrein 10 Represents a Novel Biomarker for Ovarian ...

The Human KLK8 (Neuropsin/Ovasin) Gene: Identification of Two Novel Splice Variants and Its … -
A Magklara, A Scorilas, D Katsaros, M Massobrio, … - Clinical Cancer Research, 2001 - AACR
... April 2001 ? 2001 American Association for Cancer Research ... in Epithelial Ovarian
Cancer Produces Novel Variants with Potential as Cancer Biomarkers Clin. ...

Source: Google Scholar

George Mason University Researchers Partner To Discover Novel Biomarkers For Exposure To Infectious Diseases
Researchers at George Mason University's National Center for Biodefense and Infectious Diseases and its Center for Applied Proteomics and Molecular Medicine are merging their expertise in host-pathogen biology, proteomics and nanotechnology to discover tissue and bloodborne markers that could be used for the early detection of exposure to infectious diseases.

Funded by the U.S. Department of Energy, these efforts may help save the lives of civilians and military forces exposed to biological weapons or other emerging infectious diseases, such as influenza and SARS.

"This collaboration illustrates how proteomic technologies combined with unique nanotechnology methodology can be used to better understand, diagnose and treat infectious diseases," says Charles Bailey, NCBID executive director.
A major goal of the program, which initially focuses on anthrax and tularemia, is to discover protein biomarkers that could be used to identify the onset of an infectious disease before a patient exhibits symptoms, explains Bailey. "A pre-symptomatic diagnosis of these often fatal diseases enables physicians to begin immediate lifesaving treatment for the patient. The earlier, the better."

Using cutting-edge proteomic technologies and nanotechnology-based devices invented by CAPMM scientists, the research will concentrate on the discovery, collection and analysis of potential infectious diseases biomarkers found in the blood. Comparing the differences between pre- and post-symptomatic biomarkers may result in early detection of biological agent exposure and disease onset, and immediate monitoring of patient response to medical intervention.

"We have developed new classes of biomarker discovery technologies that combine high resolution mass spectrometry and nanoparticles," says Lance Liotta, CAPMM co-director. "The investment that the university made in personnel and equipment to establish our two centers is paying dividends, and now we can leverage this investment to find specific bloodborne markers of early infection by some very nasty bugs."

Findings also may help determine if military personnel have been successfully immunized against infectious diseases before they enter an area that poses the threat of exposure to biological agents, and aid in drug discovery for certain geographic strains of diseases that are drug resistant.

"As a microbiologist by training, I'm very excited to bring the one-of-a-kind proteomic technologies and nanotechnologies we have developed for biomarker discovery for cancer and other diseases to infectious diseases applications," says CAPMM co-director Emanuel Petricoin III. "The ability to synergize the expertise of these two centers is a great opportunity and illustrates the powerhouse research that is going on now at Mason."

This research also impacts Mason's long-range plans to be a major player in biodefense and infectious diseases research, Bailey adds.

"Once our Biomedical Research Laboratory opens in late 2009, we'll have the highly specialized facility and equipment needed for next-level research utilizing animal studies," he says. "Preliminary data obtained from our current work may lead to additional funding opportunities or collaborative work with other laboratories."

http://www.gmu.edu
 
 
 
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