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Recent News and Articles on the Keywords: may underlie + african americans + differences  Related to the article below (Last Update: 5/12/2008)

Uneasy relations between many races
Contra Costa Times, CA - Apr 13, 2008
The survey also reported high levels of isolation among the groups, which may underlie and reinforce racial tensions. It found 73 percent of Latinos said ...
Obama's World, Part II
FrontPage magazine.com, CA - May 8, 2008
It is precisely those views that underlie her support for black empowerment, an ideological obsession that, as in the case of Jeremiah Wright, sometimes has ...

MinnPost.com
Tuesday's elections will gauge extent of Wright damage to Obama
MinnPost.com, MN - May 5, 2008
Deep psychological and anthropological factors underlie attitudes toward women. "The challenge for women competing in politics or business is less misogyny ...
Nation and world briefs May 2
New Mexican, NM - May 1, 2008
Stark statistics underlie the initiative by the national governing body for swimming. Black children drown at a rate almost three times the overall rate. ...
New study: 58 percent of black children can't swim
Munster Times, IN - May 1, 2008
"There are African-Americans who swim, but they're in the background," Jones said. "People only pay attention when you're in the limelight. ...
Source: Google News

Race and Sex Differences in Cutaneous Pain Perception -
D Sheffield, PL Biles, H Orom, W Maixner, DS Sheps - Psychosomatic Medicine, 2000 - Am Psychosomatic Soc
... activation and opioid activity, may underlie sex differences ... a lesser extent, sex
differences in ratings ... thermal pain perception: African Americans were more ...

for the African-American Heart Failure Trial Investigators -
AL Taylor, S Ziesche, C Yancy? - Combination of isosorbide dinitrate and hydralazine in …, 2004 - Mass Med Soc
... is that genetic variability may underlie drug-response ... is some evidence of racial
differences in the ... for the African-American Heart Failure Trial Investigators ...

Novel Single Nucleotide Polymorphisms in the Distal IL-10 Promoter Affect IL-10 Production and … -
AW Gibson, JC Edberg, J Wu, RGJ Westendorp, TWJ … - The Journal of Immunology, 2001 - Am Assoc Immnol
... high IL-10 production, and it is interesting to speculate whether this difference
may underlie, in part, the higher susceptibility of African-Americans to SLE. ...

Racial Differences in Factors that Influence the Willingness to Participate in Medical Research … -
VL Shavers, CF Lynch, LF Burmeister - Annals of Epidemiology, 2002 - Elsevier
... 31]; and factors that underlie African American participation and ... to medical research
among African Americans do not ... determine factors that may be associated ...

Racial Differences Pertaining to a Belief about Lung Cancer Surgery: Results of a Multicenter Survey -
ML Margolis, JD Christie, GA Silvestri, L Kaiser, … - Annals of Internal Medicine, 2003 - annals.highwire.org
... of current mistrust and disenfranchisement of African-American patients in ... diverse
attitudes and beliefs may underlie other racial differences in health ...

Hypertension, glomerular number, and birth weight in African Americans and white subjects in the … -
MD Hughson, R Douglas-Denton, JF Bertram, WE Hoy - Kidney International, 2006 - pt.wkhealth.com
... African Americans and white subjects and whether racial differences in glomerular
number may underlie the greater risk of African Americans for hypertensive ...

differences in prostate cancer growth: Apoptosis and cell proliferation in Caucasian and African- … -
Y Guo, DB Sigman, A Borkowski, N Kyprianou - The Prostate, 2000 - doi.wiley.com
... determinants of tumor growth that may underlie the ethnic ... Downregulation of bcl-2
expression may be potentially ... in prostate tumors from African-American men. ...

Trends and Racial Differences in Birth Weight and Related Survival -
GR Alexander, ME Tompkins, MC Allen, TC Hulsey - Maternal and Child Health Journal, 1999 - Springer
... the content and qualityof the health care services received, may underlie these
racial differences in the mortality risk of some African-American mac- rosomic ...

Excess of Rare Amino Acid Polymorphisms in the Toll-like Receptor 4 in Humans -
I Smirnova, MT Hamblin, C McBride, B Beutler, A Di … - Genetics, 2001 - Genetics Soc America
... number of low-frequency variants may underlie disease susceptibility ... mode of evolution
of a gene may provide insights ... D value in the African American and pooled ...

Fcgamma RIIa polymorphism in systemic lupus erythematosus -
LJC Smyth, N Snowden, D Carthy, C Papasteriades, A … - British Medical Journal, 1997 - ard.bmj.com
... The functional differences between R and H ... containing predominantly IgG2 autoantibodies
may underlie the reported ... with SLE and nephritis in African-Americans. ...

Source: Google Scholar

Immune System Variations May Underlie Differences In MS Between African Americans And Caucasians

A new report shows differences in immune system responses between a group of African Americans with MS compared with Caucasians. Previous research had shown that clinical symptoms differ between these groups, and the current findings may help to explain why. Drs. John R. Rinker II, Anne Cross (Washington University in St. Louis) and colleagues have published this study in the July 3 issue of Neurology (2007;69:68-72). Dr. Rinker was supported by a 2006-2007 Serono-Pfizer Clinical Fellowship of the National MS Society.

Background: Generally, the risk of MS in African Americans is around half that of Caucasian Americans. Researchers have previously reported significant differences in the clinical characteristics of MS in African Americans and Caucasian Americans: in that study, African Americans tended to have a more aggressive course of disease, were at higher risk for developing mobility impairments, were more likely to develop MS later in life, and were at higher risk for having symptoms restricted to the optic nerve and spinal cord (Neurology 2004;63[11]:2039-45).

Study and Results: The team sought to determine if differences in the immune system which launches an attack on the brain and spinal cord in MS underlie these clinical differences. They reviewed the medical records of 66 African Americans and 132 Caucasian Americans with MS for whom results of cerebrospinal fluid (CSF) tests were available.

This test is often given to help confirm the diagnosis of MS. The CSF of people with MS usually contains elevated levels of antibodies called IgG, as well as a specific group of proteins called oligoclonal bands. These findings indicate an abnormal immune response within the central nervous system.

The group found that IgG antibodies in the spinal fluid were on average 29% higher in African Americans than in Caucasian Americans.

The study also confirmed previous reports that African Americans tended to need walking aids sooner than Caucasians (on average, African Americans had MS for nine years before needing ambulatory assistance such as a cane, compared to 17 years for Caucasians). However, the study did not find that higher antibody levels could predict earlier need for ambulatory assistance.

The authors caution that the results may be affected by the fact that patients for whom CSF samples were available may have had the test performed to help diagnose unusual courses of MS such as very mild or very aggressive forms. They add that the challenge facing researchers now is to understand how this increased immune response relates to the differences in clinical symptoms.

http://www.nationalmssociety.org

 
 
 
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