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Recent News and Articles on the Keywords: some offer + important diabetes + diabetes  Related to the article below (Last Update: 5/12/2008)

With changes in how health care is delivered and financed, the ...
Minneapolis Star Tribune, MN -
Providers and insurers would be encouraged to offer the service to all Minnesotans. Some providers could offer one-price "baskets" of care for specific ...
Health care bill calls for healthier citizens, plus more coverage ... Minneapolis Star Tribune
all 62 news articles »
Low-cost clinics vital for many uninsured Utahns
Salt Lake Tribune, United States -
Charged on a sliding scale, clients seek care that ranges from prenatal visits to immunizations to help with managing diabetes or cardiovascular disease. ...

The Money Times
Scientists find something good about big bottom
Xinhua, China - May 6, 2008
BEIJING, May 7 (Xinhuanet) -- A type of fat that accumulates around the hips and bottom may actually offer some protection against diabetes, US researchers ...
Having a big bum may protect you from diabetes! News-Medical.net
Scientists find something good about a big bottom China Daily
all 82 news articles »
Medical Travel Aid
Tumbler Ridge News,  Canada -
Accommodation is particularly important and many centres provide medical rates. I have researched Edmonton, Grande Prairie, Dawson Creek and Fort St. John ...
Surgery Shows Promise For Treatment of Diabetes
Washington Post, United States - May 3, 2008
"It's a surgical solution to diabetes." While many surgeons share Rangraj's enthusiasm, and some diabetes experts agree that the operation and similar ones ...
Pet store owner changes stock after food recall
Staunton News Leader, VA -
Sprouse's 7-year-old German shorthaired pointer, Lucy, was diagnosed with diabetes about a month ago; her sugar levels were five times higher than they ...
Penobscot launches $6M endowment fund for youth club
Indian Country Today, NY - May 11, 2008
''So we're setting up the endowment fund to extend the programs we offer and to keep the programs going. One of the worst things is to set up a successful ...
Genomic Research and Personalized Medicine: An Expert Interview
Medscape (subscription) - May 8, 2008
In addition, there is a lot of excitement now as we begin to identify genetic risk factors for an ever-longer list of diseases that includes diabetes and ...

Malaysia Star
Rich in nutrients
Malaysia Star, Malaysia - May 7, 2008
In fact, when left intact in their natural state, whole grains offer more health benefits. Before we unravel their goodness, let?s examine a grain at close ...
New Ford hospital strives for 5-star treatment
Detroit Free Press, United States - May 9, 2008
"We have an epidemic of obesity, high blood pressure, diabetes -- things very much affected by diet and exercise and lifestyle. ...
Source: Google News

Diet, Lifestyle, and the Risk of Type 2 Diabetes Mellitus in Women. -
FB Hu, JAE Manson, MJ Stampfer, G Colditz, S Liu, … - Obstetrical & Gynecological Survey, 2002 - obgynsurvey.com
... Of these measures, weight control seems to offer the most ... issues, which are at least
as important to our ... health and, in fact, often contribute to some of the ...

US public health and the 21st century: diabetes mellitus -
J McKinlay, L Marceau - The Lancet, 2000 - Elsevier
... We discuss some limitations of US public health and identify new perspectives which
offer promise ... access and utilisation are therefore critically important. ...

Prevention of autoimmune diabetes in NOD mice by 1, 25 dihydroxyvitamin D 3 -
C Mathieu, M Waer, J Laureys, O Rutgeerts, R … - Diabetologia, 1994 - Springer
... anti-CD3 stimulation (Table 2). Some known immune ... but more impor- tantly, clinical
diabetes was even ... clearance of the drug, could offer important advantages in ...

Screening for type 2 diabetes. -
MM Engelgau, KM Narayan, WH Herman - Diabetes Care, 1910 - ncbi.nlm.nih.gov
... models have helped to answer some of the ... Diabetes Prevention Program, may eventually
offer more direct ... It will be important to use comprehensive cardiovascular ...

Psychosocial factors in juvenile diabetes: A review -
SB Johnson - Journal of Behavioral Medicine, 1980 - Springer
... These difficulties are characteristic of only some youngsters with diabetes. ...
There is little doubt that some children with diabetes ...

An Update on Perioperative Management of Diabetes -
SJ Jacober, JR Sowers - Archives of Internal Medicine, 1999 - Am Med Assoc
... It is also important to understand this regimen's ability ... in insulin-treated patients
with type 2 diabetes. ... widely used in Europe and offers some advantages in ...

A survey of diabetes care in general practice in England and Wales -
M Pierce, G Agarwal, D Ridout - British Journal of General Practice, 2000 - ingentaconnect.com
... Many practices now offer some diabetes care in the form ... registers; practice nurses
with some knowledge of ... Diabetes-related activity An important result is the ...

… Diabetes A Common Agenda for the American Cancer Society, the American Diabetes Association, and the … -
H Eyre, R Kahn, RM Robertson, NG Clark, C Doyle, Y … - Circulation, 2004 - Am Heart Assoc
... for clinicians to focus on important risk factors ... Fourth, this collaboration offers
new opportunities for ... Indeed, for some health indicators, the goals serve ...

A Diabetes Report Card for the United States: Quality of Care in the 1990s -
JB Saaddine, MM Engelgau, GL Beckles, EW Gregg, TJ … - Annals of Internal Medicine, 2002 - annals.highwire.org
... care systems for a population, and they offer a wayto ... Some measures came exclusively
from NHANES III, and ... of diabetes care in several important subgroups, such ...

… When Choosing a Coronary Revascularization Strategy The Diabetes-Percutaneous Transluminal Coronary … -
RE Kuntz - Circulation, 1999 - Am Heart Assoc
... that may cause future clinically important coronary narrowings ... including the presence
of diabetes mellitus ... the other hand, appears to offer some protection from ...

Source: Google Scholar

While Most Diabetes Drugs Provide Similar Glucose Control, Some Offer Important Advantages, New Review Shows
Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS' Agency for Healthcare Research and Quality. A version of the analysis was posted today in the on-line version of Annals of Internal Medicine.

The federally funded analysis is based on scientific evidence found in 216 published studies. The report summarizes the effectiveness, risks, and estimated costs for 10 drugs: acarbose (sold as Precose), glimepiride (Amaryl), glipizide (Glucotrol), glyburide (Micronase, DiaBeta, Glynase PresTab), metformin (Glucophage, Riomet, Fortamet), miglitol (Glyset), nateglinide (Starlix), pioglitazone (Actos), repaglinide (Prandin), and rosiglitazone (Avandia).
Type 2 diabetes is an increasingly common chronic disease that occurs in people who have difficulty converting glucose (a sugar) into energy. Blood glucose levels are high either because their cells are resistant to insulin (a hormone that helps convert glucose into energy) or because their pancreas does not produce enough insulin. Diabetes can cause severe problems with the heart, eyes, kidneys, and nerves. Obesity increases the risks of developing type 2 diabetes. From 1980 through 2005, the number of Americans diagnosed with diabetes soared from 5.6 million to 15.8 million.

"As more people are diagnosed with type 2 diabetes and with the growing array of treatment choices, this is a landmark review,'' said AHRQ Director Carolyn M. Clancy, M.D. "This summary of scientific evidence is not only an important tool for clinicians and patients seeking the most appropriate therapy, but it also points out in what areas we need more research to confront this disease."

As new classes of oral diabetes medications have become available, patients and clinicians have faced a growing list of treatment options. Earlier scientific reviews have highlighted some differences between medications, but AHRQ's new analysis is the first to summarize evidence on the effectiveness and adverse events for all approved oral medications commonly used in the United States for type 2 diabetes.

Diabetes patients typically are monitored with tests that check the percentage of hemoglobin A1c (HbA1c) in their blood. Checking for HbA1c is a more reliable indicator of chronic high blood sugar than checking blood glucose itself. According to the AHRQ review, most diabetes drugs offer about a one point absolute reduction in HbA1c. In those cases, for example, a diabetes patient's HbA1c might drop from 8 to 7 (with 5 being normal in patients who don't have diabetes). Nateglinide, acarbose, and miglitol lower HbA1c by about half that much. Combining diabetes medications, evidence shows, often works better at reducing HbA1c.

AHRQ's analysis of published studies, completed by the Agency's Johns Hopkins University Evidence-based Practice Center in Baltimore, also concluded:

-- Metformin and acarbose do not increase weight among diabetes patients. Other diabetes drugs (glimepiride, glipizide, glyburide, pioglitazone, repaglinide, and rosiglitazone) have been shown to increase weight by an average of 2 pounds to 11 pounds.

-- Blood levels of low-density lipoprotein, which is known as "bad cholesterol" because it may amplify risks of heart attack and stroke, consistently decrease (by about 10 milligrams per deciliter) in patients taking metformin and increase (by similar amounts) in patients taking rosiglitazone and pioglitazone.

-- Pioglitazone and rosiglitazone cause a small but significant increase in high-density lipoprotein, often called "good cholesterol" because it promotes the breakdown and removal of cholesterol from the body.

-- Glimepiride, glipizide, glyburide, and repaglinide are associated with hypoglycemia (when blood glucose levels go too low) more than other diabetes drugs.
-- Metformin and acarbose are generally more likely than other diabetes medications to cause gastrointestinal problems such as diarrhea. Patients who used metformin alone were more likely to experience problems than those using the drug at a lower dose in combination with glimepiride, glipizide, glyburide, pioglitazone, or rosiglitazone.

-- Patients who take pioglitazone and rosiglitazone have a greater risk of congestive heart failure compared with those who take metformin, glimepiride, glipizide, or glyburide. While one recent analysis raised the possibility that rosiglitazone may also increase heart attack risks, authors of the AHRQ analysis concluded that current evidence is not sufficient to make a meaningful assessment.

-- More, longer studies are needed to understand the impact of oral diabetes drugs on patients' quality of life and whether long-term use causes adverse side effects or reduces important complications of diabetes such as heart disease and kidney disease. Additional research is needed to study interactions between the drugs and to compare therapeutic combinations of the drugs, according to the report.

The report, Comparative Effectiveness and Safety of Oral Diabetes Medications for Adults with Type 2 Diabetes, is the newest analysis from AHRQ's Effective Health Care program, authorized by the Medicare Prescription Drug, Improvement and Modernization Act. That program represents an important federal effort to compare alternative treatments for health conditions and make the findings public. The program is intended to help patients, doctors, nurses, and others choose the most effective treatments.

http://www.effectivehealthcare.ahrq.gov
 
 
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