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Recent News and Articles on the Keywords: chronic constipation + miralax + safe  Related to the article below (Last Update: 5/12/2008)

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Source: Google News

Comparison of Polyethylene Glycol 3350 and Lactulose for Treatment of Chronic Constipation in … -
DA Gremse, J Hixon, A Crutchfield - Clinical Pediatrics, 2002 - cpj.sagepub.com
... term treatment of adults with chronic constipa- tion ... lactulose in the treatment
ofchronic constipation in children ... received either PEG 3350 (Miralax, Brain- tree ...

Safety of Polyethylene Glycol 3350 for the Treatment of Chronic Constipation in Children -
DS Pashankar, V Loening-Baucke, WP Bishop - Archives of Pediatrics and Adolescent Medicine, 2003 - Am Med Assoc
... Conclusions Long-term PEG therapy is safe and is ... is supplied as a powder (MiraLax;
Braintree Laboratories ... older than 2 years with chronic constipation who were ...

Polyethylene Glycol Without Electrolytes for Children With Constipation and Encopresis. -
V Loening-Baucke - Journal of Pediatric Gastroenterology and Nutrition, 2002 - jpgn.org
... glycol electrolyte solution is effective, safe, well tolerated ... treatment of children
with chronic constipation and encopresis ... MiraLax did not cause any clinical ...

Efficacy and Safety of Traditional Medical Therapies for Chronic Constipation: Systematic Review -
D Ramkumar, SSC Rao - The American Journal of Gastroenterology, 2005 - Blackwell Synergy
... Lactulose appears to be an effective and safe agent for use in idiopathic ... In an
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Overnight efficacy of polyethylene glycol laxative -
JA Di Palma, JR Smith, MB Cleveland - American Journal of Gastroenterology, 2002 - Blackwell Synergy
... a 68-g dose of PEG-3350 laxative (MiraLax) provided safe and effective ... 3350, NF powder
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Polyethylene glycol 3350 without electrolytes: A new safe, effective, and palatable bowel … -
DS Pashankar, A Uc, WP Bishop - The Journal of Pediatrics, 2004 - Elsevier
... of a virtually tasteless powder (MiraLax; Braintree Laboratories ... appears to be a
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CONSTIPATION -
A Wald - Medical Clinics of North America, 2000 - Elsevier
... The efficacy of docusates for chronic constipation is highly questionable, however,
and they are ... more than 2 to 3 times per week, they are safe and effective ...

Miracle Laxative? -
WP Bishop - Journal of Pediatric Gastroenterology and Nutrition, 2001 - jpgn.org
... available to us therefore suggests that MiraLax and related products are at least
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Encopresis. -
V Loening-Baucke - Current Opinion in Pediatrics, 2002 - co-pediatrics.com
... MiraLax was effective, safe, and palatable ... The management of chronic constipation
requires considerable patience and effort on the part of the child ...

… -Controlled Trial of Polyethylene Glycol Laxative for Chronic Treatment of Chronic Constipation -
JA DiPalma, MB Cleveland, J McGowan, JL Herrera - The American Journal of Gastroenterology, 2007 - Blackwell Synergy
... renal failure, ascites, other known chronic bowel, liver ... significant differences
between MiraLAX and placebo ... and effective for treating constipation in adult ...

Source: Google Scholar

MiraLax safe for chronic constipation

Last Updated: 2007-07-24 15:49:57 -0400 (Reuters Health)

By David Douglas

NEW YORK (Reuters Health) - MiraLax, which is currently available over-the-counter in the U.S, appears to remain safe and effective when use is extended for up to 6 months in patients with chronic constipation, researchers report in the American Journal of Gastroenterology.

This study extends the formal clinical investigation on the safety of the drug, also known as polyethylene glycol (PEG) 3350, and establishes that it is safe for long-term use, lead investigator Dr. Jack A. DiPalma told Reuters Health.

Compared with a placebo, MiraLax was effective and had an excellent safety profile," he said.

DiPalma of the University of South Alabama College of Medicine in Mobile and colleagues note that MiraLax is currently approved for the short-term treatment of occasional constipation.

To examine the effects of long-term use, the researchers studied 304 patients with chronic constipation. At the beginning of the study, constipation was confirmed over a period of 14 days. The patients were then randomly assigned to a single daily dose of MiraLax or placebo for 6 months.

Using relief of constipation of 50 percent or more of the time as a measure of effectiveness, the team established that at 6 months, 52 percent of PEG patients and 11 percent of placebo patients had successful responses. The results were similar in a subgroup of 75 elderly subjects.

Diarrhea, flatulence and nausea were more common in the MiraLax patients, but individually these conditions were not significantly worse than with placebo.

This study provides evidence that MiraLax is safe and effective for treating constipation in adult and elderly patients for up to 6 months, the investigators conclude.

SOURCE: American Journal of Gastroenterology, July 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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