Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide … -
W Focuses, NPG Contact - The EMBO Journal, 1997 - nature.com
The crystal structure of the phosphorylated, activated form of the insulin
receptor tyrosine kinase in complex with a peptide substrate and an ATP analog
has been determined at 1.9 ? resolution. The activation loop (A-loop) of ...

A generalization of Brouwer?s fixed point theorem -
S Kakutani, PDF File, DV File, DMJ Contact - Duke Math. J, 1941 - projecteuclid.org
Page 1. A GENERALIZATION OF BROUWERS FIXED POINT THEOREM BY SHIZUO IAKUTANI The
purpose of the present paper is to give a generalization of Brouwer?s fixed point
theorem (see [111), and to show that this generalized theorem implies the ...

Monotone (nonlinear) operators in Hilbert space -
GJ Minty, PDF File, DV File, DMJ Contact - Duke Math. J, 1962 - projecteuclid.org
Page 1. MONOTONE (NONLINEAR) OPERATORS IN HILBERT SPACE 1. IntrodUction. Let
be a Hilbert space, with real or complex scalars, and with inner product .(x,
y}. For C E, we call a (not necessarily linear) operator F: -- ...

Role of integrins in regulating epidermal adhesion, growth and differentiation -
W Focus, NPG Contact - The EMBO Journal, 2002 - palgrave-journals.com
Mammalian epidermis is renewed throughout life by proliferation of a
multipotential stem cell population and terminal differentiation of stem cell
progeny. In recent years, extracellular matrix receptors of the integrin ...

All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral -
W Focuses, NPG Contact - The EMBO Journal, 1998 - nature.com
Ras, Rap1 and Ral are related small GTPases. While the function of Ras in signal
transduction is well established, it has been recognized only recently that Rap1
and Ral also are activated rapidly in response to a large variety of ...

From the following article
… , TA Rosen, JD Levine, D Julius, NPG Contact - Nature, 1997 - nature.com
Nature is the international weekly journal of science: a magazine style journal
that publishes full-length research papers in all disciplines of science, as well
as News and Views, reviews, news, features, commentaries, web focuses and more ...

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin- … -
W Focuses, NPG Contact - The EMBO Journal, 1998 - nature.com
The focal adhesion kinase (FAK) protein-tyrosine kinase (PTK) links
transmembrane integrin receptors to intracellular signaling pathways. We show
that expression of the FAK-related PTK, Pyk2, is elevated in fibroblasts ...

From the following article -
KW Finkel, NJ Holbrook, NPG Contact - Nature, 2000 - nature.com
Although maximum life span is the most relevant and defined endpoint with regard
to ageing, it seems likely that in large multicellular organisms ageing need not
proceed uniformly. This concept of non-uniform or focal ageing, or what has ...

Take five?BACE and the gamma-secretase quartet conduct Alzheimer's amyloid beta-peptide generation -
W Focuses, NPG Contact - The EMBO Journal, 2004 - nature.com
In 1959, Dave Brubeck and Paul Desmond revolutionized modern jazz music by
composing their unforgettable Take Five in 5/4, one of the most defiant time
signatures in all music. Of similar revolutionary importance for biomedical ...

On Cartan?s method of Lie groups and moving frames as applied to uniqueness and existence questions … -
P Griffiths, PDF File, DV File, DMJ Contact - Duke Math. J, 1974 - projecteuclid.org
TABLE OF CONTENTS 0. INTRODUCTION 1. TWO LEMMAS ON MAURER-CARTAN FORMS 2. LIE
GROUPS AND MOVING FRAMES 3. EUCLIDEAN GEOMETRY () Curves in R (b) Hypersurfces
in R / 4. HOLOMORPHIC CURVES IN PROJECTIVE SPACE () Frenet frames nd the ...