Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California
blank

 

Recent News and Articles on the Keywords: cancer vaccine + innovative project + project  Related to the article below (Last Update: 5/5/2008)

Groundbreaking celebrated for new $100M centre for vaccine research
Laboratory Products News, Canada - Apr 30, 2008
Senior company and Ontario provincial government officials join to kick off groundbreaking for the project. (Photo: Rodney Daw, ro... Artist's sketch of the ...
Colleges, State In Money Tug-Of-War
Tampa Tribune, FL - Apr 22, 2008
They want to spend most of it on a project to develop innovative energy sources in Florida, a project that received lower marks from the same group of ...
OTCPicks.com: OTCPicks.com Stocks to Watch for Friday, May 2nd ...
Trading Markets (press release), CA - May 2, 2008
May 1 - Zoro Mining Has Contracted for 8000 Meters of Diamond Drilling at Its Don Beno Project, Region III Chile Zoro Mining Corp. ...MESA - NETM
JUICE Pharma Announces ?bigtique? Business Model
PharmaLive.com (press release), PA - May 2, 2008
JUICE Pharma is the professional agency responsible for the global launch of GARDASIL, Merck?s cervical cancer vaccine, among other agency-of-record work on ...
Penn State scientists elected to National Academy of Sciences
Penn State Live, PA - Apr 30, 2008
... and that patients with this bacteria also were at significant risk for developing stomach cancer. His current research project is studying the molecular ...
Full Text
Science Magazine (subscription) - Apr 24, 2008
It expects to begin trials with a cancer vaccine tailored to individual patients in 2009, says CEO Yuri Gleba. Bayer's move is a healthy sign of regrowth ...

Express Pharma
Mission immunisation
Express Pharma, India - Apr 25, 2008
He adds, "In addition to this, we are also developing seasonal influenza, pandemic influenza and aerosol measles vaccines under a project with WHO. ...
Need for Products Seen As Driver
San Fernando Valley Business Journal Online (subscription), CA - Apr 28, 2008
?The (Human) Genome project opened up a whole new world of genetics and genomics. At the same, time devices started to boom with the development of balloon ...
Incorporating Healthcare Into CSR Programs
China CSR, China - Apr 21, 2008
And then in December 2007, a month after the Gates' announcement, the United Nations Development Programme and the Chang Ai Media Project hosted the launch ...
Sanofi Pasteur invests 100 million Canadian dollars in an R&D ...
Canada NewsWire (press release), Canada - Apr 15, 2008
For this project, sanofi pasteur is pleased to partner with the Government of Ontario, which will contribute 13.9 million Canadian dollars through the ...SNY - LON:CNT
Source: Google News

Preserving Innovation Under Increasing Accountability Pressures: The Health Promotion Investment …
P Hawe, A Shiell, B Corti, RJ Donovan, RM Castine, … - Perspective - healthpromotion.org.au
... mechanism to protect within-practice innovation in health ... strategies for breast and
cervical cancer screening must ... Influenzae Type b (Hib) Vaccine in Children ...

Cuba-innovation through synergy -
H Thorsteinsd?ttir, TW Saenz, U Quach, AS Daar, … - Nature Biotechnology, 2004 - nature.com
... is not only the recipient of innovation but also ... Delhi), to manufacture hepatitis
B vaccine, and CIMAB ... Mississauga)), to develop and market cancer therapeutics. ...

The Deep South Network for Cancer Control: Eliminating Cancer Disparities Through Community-Academic … -
EE Partridge, MN Fouad, AW Hinton, CM Hardy, N … - Family & Community Health, 2005 - familyandcommunityhealth.com
... investigators, and develop and test innovative, community-based ... in an industry-sponsored
HPV vaccine trial at ... to the SELECT prostate cancer prevention trial in ...

[DOC] The Nature and the Extent of the Market for Technology in Biopharmaceuticals -
A Arora, A Gambardella, F Pammolli, M Riccaboni - International Conference on Technology Policy and Innovation …, 2000 - unisi.it
... December 2000. This paper is part of the activities of the EPRIS Project (European
Pharmaceutical Regulation & Innovation Systems), University of Siena, Italy. ...

INNOVATIVE TREATMENTS FOR PANCREATIC CANCER -
SM Lieberman, H H?rig, HL Kaufman - Surgical Clinics of North America, 2001 - Elsevier
... CURRENT ACTIVE NCI-SPONSORED CLINICAL TRIALS FOR INNOVATIVE TREATMENT OF PANCREATIC
CANCER (AS OF 10/12 ... NCI-94-C-0096, Immunotherapy, I, K-ras, Peptide vaccine. ...

Preventing cervical cancer in low-resource settings: Building a case for the possible -
AE Pollack, VD Tsu - International Journal of Gynecology and Obstetrics, 2005 - Elsevier
... the results of ACCP research on innovative approaches to ... HPV) screening and an HPV
vaccine, and reviewed ... broader public health impact of cervical cancer in the ...

The business of making vaccines -
C Sheridan - Nature Biotechnology, 2005 - nature.com
... for its product, Gardasil, which protects against two HPV strains implicated in
cervical cancer and two ... The pace of innovation in the vaccine industry has ...

The discovery value of" Big Science" -
J Esparza, T Yamada - Journal of Experimental Medicine, 2007 - Rockefeller Univ Press
... The Global HIV Vaccine Enterprise. Int. Microbiol. ... Stokes, DE 1997. Pasteur's quadrant:
basic science and technological innovation. ... J. Natl. Cancer Inst. ...

[BOOK] Market Structure and Innovation -
MI Kamien, NL Schwartz - 1982 - books.google.com
... deficit; eliminate famine; and cure cancer, heart disease ... stock-in-trade (in his
projects of encyclopedism ... others claim that the nature of innovative activity ...

[BOOK] Science and Innovation: The US Pharmaceutical Industry During the 1980s
A Gambardella - 1995 - books.google.com
SCIENCE AND INNOVATION The US pharmaceutical industry during the 1980* ALFONSO
GAMBARDELLA ... (Some of them even win Nobel prizes!) Many small innovative firms in ...

Source: Google Scholar

Innovative Project To Develop Cancer Vaccine
Biodesign Institute researchers have received nearly $9 million in grants to develop a preventive vaccine against cancer.

Stephen Albert Johnston, PhD, director of the institute's Center for Innovations in Medicine, will focus his research project on breast cancer. Johnston is one of only two recipients in the nation bestowed with a five-year, $7.5 million grant from the Department of Defense's Innovator Award, funded through its Breast Cancer Research Program. His Biodesign research colleague, Douglas Lake, PhD, will lead a three-year $1.2 million project from the W. M. Keck Foundation to take the basic technology and see whether it could be applied to several other forms of cancer.
The grants mark the first major federal and private awards for such an approach and ramp up a cancer research collaborative initiative with the Mayo Clinic.

Cancer is the second leading cause of death in the U.S., with an estimated 1.45 million cases of cancer diagnosed this year. More than 560,000 people will die from the disease.

Breast cancer is the second leading cause of death in women. The Department of Defense, using appropriations from a congressionally directed medical research program, has sought to eradicate breast cancer by funding innovative, high-impact research through a partnership of scientists and consumers. The Innovator Award recognizes individuals who have a "history of visionary scholarship, leadership and creativity."

"Breast cancer's course is often long and devastating and, despite advances in diagnosis and treatment, one in five women still succumb to the disease," said Johnston. "It's time to fundamentally rethink how we approach this problem. Our goal, based on some promising preliminary results, is to see if we can make a vaccine that would be given to all adult women to prevent the occurrence of breast cancer"

Johnston notes that the most successful medical intervention in history has been the development of vaccines against infectious disease. "Developing a cancer vaccine would be the perfect solution, not only in eliminating cancer mortality, but also potentially some of the costs of diagnosis and treatment."

The W.M. Keck Foundation Award will further push the boundaries of cancer vaccine research by laying the groundwork for breakthrough discoveries to broaden the team's approach to other cancers.
"It's been well-established that cancers create foreign proteins that the immune system can recognize," said Douglas Lake, who will lead the Keck Foundation project. "If we could pre-immunize an individual with a collection of proteins that effectively represent any foreign protein that a breast tumor would produce, the immune system would arm itself against breast cancer," said Lake. "And, if the platform technology proves successful, it could be applied to other cancers."

The Biodesign Institute duo will lead a highly interdisciplinary team of scientists and clinicians, which involves renowned collaborators from other institutions including: Laurence Miller, MD, Mayo Clinic director for research and Richard Smith, PhD, chief scientist at Pacific Northwest National Labs.

The research team, utilizing the latest advances in genomics, proteomics and immunology, wants to find a number of common signatures that occur across a wide spectrum of breast tumors.

"This has truly been a collaborative effort, with significant contributions from both organizations," according to Miller. "I am thrilled that this is going forward, and am also pleased to see this important project launching our joint efforts in the Mayo Clinic/ASU Center for Cancer-related Convergence, Cooperation and Collaboration (MAC5)."

The research work will be performed at the Biodesign Institute's Center for Innovations in Medicine and Mayo Clinic's new Collaborative Research Building. This project is the first major initiative undertaken under the MAC5 umbrella partnership. Earlier, the organizations invested seed funds including private funding from Mayo and ASU funding made possible by the Arizona voter-approved, Proposition 301 Technology Research and Infrastructure Fund (TRIF). The funds allowed Johnston's team to launch the project and obtain the initial supportive data. Space has been allocated at research facilities at the Biodesign Institute and on the Scottsdale campus of Mayo Clinic, with additional faculty and clinicians being hired to support the project.

To find common elements in breast cancer and other tumors, the research team will use patient and normal samples from extensive tissue banks at the Mayo Clinic. The team will develop new techniques to identify small protein fragments, or peptides, found in breast cancer cell lines and primary tumors. "The key is that these peptides have to trigger an immune response against breast tumors but not in normal cells," said Johnston.

Johnston knows demonstrating their approach will be a significant challenge. But he has been encouraged by recent mouse studies in his lab, which have identified peptides that have shown protection against breast cancer. Lake is advancing these preliminary mouse studies by identifying peptides from human tumors that are candidates for a cancer vaccine.

"We believe the technology and knowledge base now exists to determine whether or not this idea is feasible," said Johnston. "If we are successful in our approach, we hope to bring a vaccine candidate to clinical trials by the end of the grant period."

The Biodesign Institute at ASU

The Biodesign Institute at Arizona State University is focused on innovations that improve health care; provide renewable sources of energy and clean our environment; outpace the global threat of infectious disease; and enhance national security. Using a team approach that converges the biosciences with nanoscale engineering and advanced computing, the goal is to find solutions to complex global challenges and accelerate these discoveries to market. The institute also educates future scientists by providing hands-on laboratory research for more than 250 students per semester. For information, visit http://www.biodesign.asu.edu/

Mayo Clinic Cancer Center

Mayo Clinic Cancer Center is one of only 38 U.S. medical centers that have been named as a National Cancer Institute (NCI) Comprehensive Cancer Center. To receive this designation, an institution must meet rigorous standards demonstrating clinical excellence in treating cancer patients and scientific excellence in its research programs. Mayo Clinic Cancer Center is ranked by the NCI as one of the top 10 cancer centers in the nation, and is the only national, multi-site center with the NCI's Comprehensive Cancer Center designation. In Arizona, Mayo's clinical and research experts work together to address the complex needs of cancer patients, with a dedication to understanding the biology of cancer; discovering new ways to predict, prevent, diagnose and treat cancer; and transforming the quality of life for cancer patients today and in the future.

The W. M. Keck Foundation

Based in Los Angeles, the W. M. Keck Foundation was established in 1954 by the late W. M. Keck, founder of the Superior Oil Company. The Foundation's grant making is focused primarily on pioneering efforts in the areas of medical research, science and engineering. The Foundation also maintains a program to support undergraduate science and humanities education and a Southern California Grant Program that provides support in the areas of health care, civic and community services, education and the arts, with a special emphasis on children.

Source: Joseph Caspermeyer
Arizona State University
 
 
Google
Web www.iconocast.com

Search inside Iconocast for the keyword you have in mind.

Iconocast has collected more than 50,000 articles and press releases on health and science.

These are current and most up to date press releases on the subject you are searching.

We collect current health and science press releases daily from more than 5000 research and health institutes. Here is an example : The elderberry way to perfect skin

We believe if you do search inside Iconocast, you will get better results than searching the web alone.

 
 
Continue News With: News4 ; News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services.

 

Iconocast Home Page

Contact Iconocast

© 2003-07. ICONOCAST is a trademark of iconocast.com.