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Recent News and Articles on the Keywords: bioengineered skin + skin substitute + approach  Related to the article below (Last Update: 5/12/2008)

Anti-aging aftershave hits male cosmetics market
CosmeticsDesign.com, France -
DermaLastyl-m aftershave contains elastatropin, a bioengineered form of the tropoelastin (a building block of human elastin) which appears in many of the ...
The secret of beautiful skin
Times of India, India - Apr 14, 2008
?Most immediately, this study should lead to bioengineered skin grafts that more closely resemble the natural tone and color of recipients, which may help ...
Cosmetic Science Conference to take place in Amsterdam Fibre2fashion.com
all 2 news articles »

WVEC.com (subscription)
Artifical skin patch may help diabetics, burn victims
WVEC.com (subscription), VA - Apr 24, 2008
Unlike having a skin graft, applying bioengineered skin does not involve anesthesia or surgery. Many patients at Therapy Concepts have had complete success ...
Sold Out at Selfridges!
PR-Inside.com (Pressemitteilung), Austria - Apr 17, 2008
Dozens of women have joined a waiting list set up by Selfridges to buy a ?125 face serum that boasts the world's first and only topical bioengineered human ...
JAPAN GOVT AIMS FOR MEDICAL BREAKTHROUGHS WITH SPECIAL ZONES
Trading Markets (press release), CA - Apr 24, 2008
These include regenerative medicine, bioengineered pharmaceuticals and induced pluripotent stem cells, or iPS cells. The government will begin accepting ...

Vanderbilt University News
Vanderbilt burn expertise to assist federal battlefield injuries ...
Vanderbilt University News, TN - Apr 18, 2008
?The goal of the burn team within AFIRM is to assemble bioengineered skin substitutes containing stem cells that will regenerate better than any products ...
Source: Google News

… Modified Human Keratinocytes Overexpressing PDGF-A Enhance the Performance of a Composite Skin … -
SA Eming, DA Medalie, RG Tompkins, ML Yarmush, JR … - Human Gene Therapy, 1998 - liebertonline.com
... Bioengineered skin substitutes that use cultured keratinocytes as an ... the performance
of a skin substitute can be ... chain (PDGF-A). Composite skin substitutes of ...

Healing of Venous Ulcers of Long Duration with a Bilayered Living Skin Substitute: Results from a … -
H Brem, J Balledux, T Sukkarieh, P Carson, V … - Dermatologic Surgery, 2001 - Blackwell Synergy
... in chronic wounds and the use of bioengineered skin. ... spite of these differences in
the approach to wound ... wound prior to the application of the skin substitute. ...

… of partial thickness facial burns (comparison of topical antibiotics and bio-engineered skin … -
RH Demling, L DeSanti - Burns, 1999 - Elsevier
... Author Keywords: Partial thickness burn; Face; Bioengineered skin substitute. ... 4].
The difficulties of this approach plus the ... 2.2. Bio-engineered skin substitute. ...

Wounding of Bioengineered Skin: Cellular and Molecular Aspects After Injury -
V Falanga, C Isaacs, D Paquette, G Downing, N … - Journal of Investigative Dermatology, 2002 - nature.com
... An added advantage of this approach is that it can lead ... to know the events associated
with injury to bioengineered skin. ... Human bilayered skin substitute (HBSS). ...
-

A bilayered living skin construct (APLIGRAF?) accelerates complete closure of hard-to-heal venous … -
V Falanga, M Sabolinski - Wound Repair and Regeneration, 1999 - Blackwell Synergy
... Biological skin substitutes (bioengineered skin), such as ... a literature-guided
approach.Clin Dermatol 1994 ... M, Laszlo KA composite skin substitute (Graftskin) for ...

Tissue-Engineered Skin: Current Status in Wound Healing. -
YM Bello, AF Falabella, WH Eaglstein - American Journal of Clinical Dermatology, 2001 - dermatology.adisonline.com
... Morgan J, Yarmush M. Bioengineered skin substitutes. ... Autologous full-thickness skin
substitute for healing chronic ... Clinical Approach to Wounds: Debridement and ...

Evaluation of Tissue-Engineered Skin (Human Skin Substitute) and Secondary Intention Healing in the … -
S Gohari, C Gambla, M Healey, G Spaulding, KB … - Dermatologic Surgery, 2002 - Blackwell Synergy
... a tried and true approach well reviewed ... of pyoderma gangrenosum treated with
bioengineered skin and concomitant ... Laszlo K. A composite skin substitute (HSS) for ...

Human plasma as a dermal scaffold for the generation of a completely autologous bioengineered skin. -
SG Llames, M Del Rio, F Larcher, E Garc?a, M … - Transplantation, 2004 - transplantjournal.com
... tested on immunodeficient mice as a preclinical approach. ... The bioengineered skin
was placed orthotopically on the ... protect and hold the skin substitute in place ...

Skin Substitutes in Burns -
RL Sheridan, RG Tompkins - Burns, 1999 - Elsevier
... skin substitute is within the realm of possibility sometime in the next decade.
Just what form that substitute will take is not clear. A promising approach is ...

[PDF] HIV-1 in semen: an isolated virus reservoir -
RA Byrn, D Zhang, R Eyre, K McGowan, AA Kiessling - J Virol, 1996 - bedfordresearch.org
... 1 McCarthy M. Bio-engineered tissues move towards the clinic. ... of 11 patients who
required split-thickness skin grafts. ... At present, LSE and other bioengineered ...

Source: Google Scholar

Bioengineered Skin Substitutes Set To Approach 500 Million Dollars By The End Of The Decade
While the promise of artificial skin has been reported and debated for more than a decade, it is only recently that commercial treatments based on this family of technologies have become established. Early successes have been offset by a lack of comparative data and the custom methods used to produce and process the cellular matrices and autologous cells that comprise the majority of commercial and late-stage skin substitutes. But clinical data from a handful of approved products has demonstrated the potential of skin substitutes, particularly for the treatment of diabetic ulcers and severe burns, and has positioned this sector to achieve total revenue of 475 million dollars by 2010.
Several factors have slowed acceptance of bioengineered skin substitutes. The small biotech companies involved in creating and developing the technology typically do not have the resources for large, long-term clinical trials to provide information on the cost effectiveness of the treatment compared to conventional alternatives. Lack of cost effectiveness data is the main reason for which insurance companies are reluctant to reimburse treatment with tissue repair products. But investment from larger players and ongoing academic programs have kept the science moving forward.

Increases in disease prevalence in conditions such as diabetes will have a significant impact on demand for bioengineered skin substitutes. Other factors that will push up service-use include adverse consequences of health care, for example, drug-resistant infections and inappropriate or sub-optimal interventions.

Skin Substitutes and Cellular matrices, a recently released report, analyzes emerging therapeutics, market participants, and key regulatory and technology factors influencing this market and shaping growth prospects over the next four years. It is available from Applied Data Research by visiting: http://www.applieddata.org/Cellular_Matrices.htm
About Applied Data

Applied Data Research is a drug therapeutics consulting firm focused on medical market strategies, product commercialization, venture development, and market research. We assist medical market participants in achieving their business objectives through the creation of detailed business development strategies, product commercialization programs, and comprehensive market and technology research and analysis.

http://www.applieddata.org
 
 
 
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