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Recent News and Articles on the Keywords: brain lesions + older patients + patients  Related to the article below (Last Update: 5/12/2008)


eFluxMedia
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Irish Independent
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Daily Mail
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Source: Google News

Language dominance determined by whole brain functional MRI in patients with brain lesions -
RR Benson, DB FitzGerald, LL LeSueur, DN Kennedy, … - Neurology, 1999 - AAN Enterprises
... signal along areas of high signal gradient (brain borders, ventricle ... p = 0.227 for
the 9 largest lesions (S > 8.2). ... age 26 years, n = 9) and older group (mean ...

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on … -
WI McDonald, A Compston, G Edan, D Goodkin, HP … - Annals of Neurology, 2001 - doi.wiley.com
... that, in the absence of brain lesions, two or ... lack specificity (as in the older patient),
or when ... provide information about dissemination of lesions or events ...

Large focal tumor-like demyelinating lesions of the brain: intermediate entity between multiple … -
JJ Kepes - Ann Neurol, 1993 - ncbi.nlm.nih.gov
... The lesions presented clinically and radiologically as brain tumors (gliomas or
metastases) or as multiple cysts. Six patients were older than 57 years (2 in ...

Letter and category fluency in patients with frontal lobe lesions -
JV Baldo, AP Shimamura - Neuropsychology, 1998 - content.apa.org
... 10.1037/0894-4105.12.2.259 Keywords category & verbal fluency, 33-77 yr old patients
with frontal lobe lesions Index Terms *Brain Damage; *Classification ...

[PDF] Source memory impairment in patients with frontal lobe lesions -
JS Janowsky, AP Shimamura, LR Squire - Neuropsychologia, 1989 - cs.dartmouth.edu
... damage (in black) from the CT or MRI brain scans of ... means--23.4, 22.8 and 25.0 questions
for the patients with frontal lobe lesions, older subjects and ...

… : Basis of a New Functional Risk Profile in the Selection of Patients with Cortical Brain Lesions. -
M Hund, AR Rezai, E Kronberg, J Cappell, M … - Neurosurgery, 1997 - neurosurgery-online.com
... FIGURE 2. Patient (24-yr-old) suffering from seizures ... three-dimensional reconstruction
of the brain (B) located ... close proximity to the tumor lesion (high MEG ...

Phase II study of temozolomide in heavily pretreated cancer patients with brain metastases. -
C Christodoulou, D Bafaloukos, P Kosmidis, E … - Annals of Oncology, 2001 - pt.wkhealth.com
... patients (with measurable and nonmeasurable lesions), overall median ... in a
44-year-old man, diagnosed ... and pericardial effusions and multiple brain metastases. ...

… Seizures in Traumatic Brain Injury Rehabilitation Patients: Brain Injury Factors Causing Late … -
I Asikainen, M Kaste, S Sarna - Epilepsia, 1999 - Blackwell Synergy
... late seizure also was longer in older age groups ... posttraumatic amnesia (PTA) without
local brain lesion, should not ... Thorough follow-up of patients with TBI with ...

MR brain scanning in patients with vasculitis: differentiation from multiple sclerosis -
DH Miller, IEC Ormerod, A Gibson, E Boulay, P … - Neuroradiology, 1987 - Springer
... has proved sen- sitive in the detection of brain lesions in patients with multiple ...
with cerebrovascular disease have generally been in an older age group ...

Blood Pressure, Cognitive Functions, and Prevention of Dementias in Older Patients With Hypertension -
WH Birkenhager, F Forette, ML Seux, JG Wang, JA … - Archives of Internal Medicine, 2001 - Am Med Assoc
... at this stage may be an expression of brain lesions accompanying Alzheimer ... Medical
Research Council trial 21 of treatment in older patients with hypertension ...

Source: Google Scholar

Brain Lesions In Older Patients Evaluated
Lesions commonly seen on MRI in the brains of older patients may be a sign of potentially more extensive injury to the brain tissue, according to a recent study conducted by researchers at the Duke University Medical Center, in Durham, NC.

According to the study, hyperintense lesions are a common finding on neuroimaging and are associated with aging, medical illness and some invasive medical procedures. "These hyperintensities are seen in most everyone as we age, although they can be more severe in some than others, said Warren Taylor, MD, lead author of the study. "We feel they're important as greater severity of these lesions is associated with a number of conditions including dementia and memory problems, depression, risk of falls, incontinence, and even higher mortality," he said.
The study consisted of 82 patients age 60 and older who were not depressed and had no history of neurologic illness. Each patient underwent a brain MRI with diffusion tensor imaging (DTI). The volume of white matter lesions and gray matter lesions was measured, and fractional anisotropy was measured in the white matter of frontal regions, the internal capsule, and corpus callosum. In general, increased lesion volumes were associated with lower fractional anisotropy (FA) values; a measure of both the direction and the intensity of water diffusion and is used as a surrogate marker for tissue integrity.

"What we found in the study is that these lesions may just be the visible sign of more widespread disease in the brain. That is, in people with more severe lesions, even brain areas that appear normal on MRI may also be affected, particularly brain areas involved in reasoning," said Dr. Taylor. "One theory we've used is that lesion location may distinguish why some people with a lot of these lesions seen on MRI may get depressed or develop memory problems, while others don't have these problems and do fine. The development of depression or dementia may be because a lesion occurred in areas of the brain that help control mood or memory," he said.

The full results of this study appeared in the American Journal of Roentgenology, published by the American Roentgen Ray Society.

Source: Necoya Lightsey
American Roentgen Ray Society
 
 
 
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