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Recent News and Articles on the Keywords: fight against + fight aids + aids  Related to the article below (Last Update: 5/5/2008)

Resistance to medicines threatens war against AIDS in Africa
Radio Netherlands, Netherlands -
... which can cause AIDS has access to cheap viral-inhibitors which help keep the virus under control. That's an impressive result for the fight against ...
Ghanaian Teacher Takes Up Health in Country
AllAfrica.com, Washington -
All the way from his native country, Ghana, he is obsessed with the fight against malaria and HIV/AIDS here in Nigeria. The above provides an insight into ...
Uganda: LC5 to Punish Aids Funds Swindlers
AllAfrica.com, Washington -
CIVIL servants of Masaka district who swindle money from the Global Funds to fight AIDS, tuberculosis and malaria are in for tough times. ...
Human Protein Offers New Approach in the Fight Against AIDS
Voice of America - May 1, 2008
By V?ronique LaCapra As researchers work to defeat HIV - the virus that causes AIDS - they have developed an ever-increasing number of medications. ...
Local authorities in joint fight against HIV/AIDS
IPP Media - Guardian, United Republic of Tanzania - May 3, 2008
... sub-Saharan Africa, has been at a fore front in the fight against the spread of Human Immuno Virus and Acquired Immuno Deficiency Syndrome (HIV/AIDS). ...
Africa: Alarm Over High HIV Prevalence
AllAfrica.com, Washington -
Meanwhile, the UN has released a report on the progress made in the fight against HIV/Aids in the last seven years. Released by the UN Secretary General, ...
Cyclists Join Fight Against HIV/Aids
AllAfrica.com, Washington - Apr 30, 2008
In a bid to prevent the spread of HIV & AIDS, Namibia's leading cyclists have ganged up to join the fight against the deadly pandemic. ...
Voice of the Youth-Sierra Leone on Youth sensitization
Awareness Times, Sierra Leone -
Mr. Philip Hartling pointed out that the objectives of his organization are to fight against drug abuse, HIV/AIDS, commercial sex workers, child trafficking ...
Brown needs grassroots help on aid
guardian.co.uk, UK -
Eight years ago a Fast Track Initiative was created to do for education what global initiatives were doing for the fight against Aids, malaria and TB: poor ...
Cameroon: Workers Deplore Accidents at Workplaces
AllAfrica.com, Washington -
... brandished messages which reflected the theme of celebration, their commitment to fight HIV/AIDS, and contribute to the development of the country. ...
Source: Google News

Progress and Problems in the Fight against AIDS -
B Hirschel, P Francioli - New England Journal of Medicine, 1998 - content.nejm.org
PreviousPrevious, Volume 338:906-908, March 26, 1998, Number 13. Next Next.
Progress and Problems in the Fight against AIDS. Since this ...

Fighting against AIDS: the Brazilian experience. -
GC Levi, MAA Vit?ria - AIDS, 2002 - aidsonline.com
... The fight against the disease set the stage for a new kind of ... the rights of those
living with HIV/AIDS, or fighting against prejudice, discrimination and ...

T-Cell Subset Counting and the Fight Against AIDS: Reflections Over a 20-Year Struggle -
F Mandy, J Nicholson, B Autran, G Janossy - strategies, 2002 - doi.wiley.com
Page 1. CD4 Testing: A Twenty Year Perspective T-Cell Subset Counting and
the Fight Against AIDS: Reflections Over a 20-Year Struggle ...

[CITATION] God and the Fight Against AIDS
H Epstein - New York Review of Books, 2005

Defining and refining international donor support for combating the AIDS pandemic -
A Attaran, J Sachs - The Lancet, 2001 - Elsevier
... this pandemic has been unfolding, the fight against AIDS has been ... designated by donors
as AIDS control programmes ... The total amount of international aid to deal ...

How to lose the fight against AIDS among gay men. -
R Stall - BMJ, 1994 - ncbi.nlm.nih.gov
BMJ. 1994 Sep 17;309(6956):685-6. Click here to read How to lose the fight
against AIDS among gay men. Stall R. Publication Types ...

[CITATION] Discourses of power and empowerment in the fight against HIV/AIDS in Africa
C Baylies, J Bujra - AIDS, safety, sexuality and risk, eds. Aggleton P., P. …, 1995

The Global HIV/AIDS Pandemic, Structural Inequalities, and the Politics of International Health -
R Parker - American Journal of Public Health, 2002 - Am Public Health Assoc
... new HIV/AIDS prevention and control efforts, making its loans the single most important
source of financial resources for the global fight against the epidemic ...

Fighting HIV/AIDS: is success possible? -
S Okware, A Opio, J Musinguzi, P Waibale - Bulletin of the World Health Organization, 2001 - SciELO Public Health
... Fighting HIV/AIDS: is success possible? Sam Okware, 1 Alex Opio, 2 Joshua Musinguzi,
3 & Paul Waibale 3. Abstract The fight against HIV/AIDS poses enormous ...
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[PDF] Transmission, acute HIV-1 infection and the quest for strategies to prevent infection -
M Pope, AT Haase, H Cleaver - 2003 - microbicide.com
... 11 years in Africa's most successful fight against the epidemic ... adults are HIV-positive,
Uganda's AIDS and HIV ... Uganda's HIV-fighting mantra is referred to as ABC ...
-

Source: Google Scholar

New Discovery In The Fight Against AIDS Sees Major Decrease In Spread

Olive oil has become part of the fight against the Human Immunodeficiency Virus (HIV) -- the cause of AIDS -- thanks to the research carried out by the Bionat team, from the University of Granada, headed by Prof. Andres García-Granados, senior lecturer in Organic Chemistry. Their work shows that maslinic acid -- a natural product extracted from dry olive-pomace oil in oil mills -- inhibits serin-protease, an enzyme used by HIV to release itself from the infected cell into the extracellular environment and, consequently, to spread the infection into the whole body. They determined that the use of olive-pomace oil can produce an 80% slowing in the spread of AIDS in the body.
Maslinic or crataegolic acid is a pentacyclic terpene with antioxidant and anticancer effects found in wax from olive skin, alongside oleanolic acid. The effects of this compound in the fight against AIDS are simultaneously being studied in the UGR and in Hospital Carlos III in Madrid by a team headed by Prof. Vallejo Nájera.

Maslinic acid innovative properties stem from its powerful protease-inhibition activity, allowing researchers from Granada to register two patents on behalf of the UGR to produce drugs for treatment of diseases caused by protozoa Cryptosporidium -- a parasite causing small intestine infection and diarrhoea -- and by HIV. The University of Granada has already registered almost ten other patents related to this compound's properties.

Maslinic acid is also a very active compound in opportunistic parasitic infections seriously affecting HIV patients.

In trials carried out by these researchers with the MT2 cell line, for concentrations of 25 and 30 µg/ml maslinic acid inhibited replication of a primary HIV-1 isolate. For 25 µg/ml a decrease in the cytopathic effect and in p24 antigen levels in the supernatant culture medium was detected. For 30 µg/ml, there was total absence of the cytopathic effect and also a decrease of p24 antigen levels.

Pilot Plant

The UGR Faculty of Sciences hosts a unique maslinic acid production pilot plant where the company MANINVEST S.L. -- staffing scientists from the UGR departments of Organic Chemistry, Biochemistry and Parasitology, as well as a coordinating economist -- is carrying out research on technology implementation and business programmes tuning aimed at making manitol and maslinic and oleanolic acids programmes more profitable.

Whilst manitol is obtained from olive oil waste water (alpechín) and olive-tree leaves, both acids are extracted from dry olive-pomace oil (orujo) produced at the olive-milling stage during olive oil elaboration process.
To this day, only oleanolic acid -- produced in China -- has been marketed. However, maslinic acid has gained importance as it is not still on the market and has a greater biological activity.

Prof. Andrés García-Granados's team intends to continue working in the design and implementation of new maslinic acid by-products to fight against HIV, as well as in other innovative research projects financed by the Spanish Ministry of Science and Technology and the Andalusian Regional Government.

Reference:
Prof. Andrés García-Granados López de Hierro. Department of Organic Chemistry, University of Granada.

Source: Professor Andrés García-Granados López de Hierro
Universidad de Granada
 
 
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