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Recent News and Articles on the Keywords: specialist centres + tissue sarcoma + soft  Related to the article below (Last Update: 5/12/2008)

NHS shake-up to axe hospital services
Telegraph.co.uk, United Kingdom - May 8, 2008
It is all very well having specialist centres around the country but it is not want the public want." Andrew Lansley, the shadow health secretary, ...
Bid to calm fears over NHS overhaul The Press Association
all 170 news articles »
Health vision for east unveiled
Norfolk Eastern Daily Press, UK -
... dentists and radiotherapy services with longer GP surgery opening hours. the creation of urgent care centres and new specialist centres for stroke, ...
Conquering the divide WCIT 2008
Malaysia Star, Malaysia -
Our inability to do this could be the reason why telecentres, as well as computer and Internet centres set up by the Government in rural areas are mostly ...
Quality Assurance Specialist - Call Centre
iTWire, Australia - May 11, 2008
You will oversee the development and implementation of Call Recording within Direct Contact Centres. Your key responsibilities will include: In this role ...
Proximity is no substitute for survival
Irish Independent, Ireland - May 3, 2008
Cancer treatment is shown to be irrefutably more successful in specialist Centres of Excellence (CoE) dealing exclusively with cancer patients. ...
Developers see potential of city shopping districts
Financial News (subscription) - May 11, 2008
... a retail property specialist formerly part of the C&A group and now owned by the Swiss-based company Cofra Holding, said blending shopping centres into ...
SENIOR ACUTE AND SPECIALIST CARE COMMISSIONING MANAGER
Health Service Journal, UK - May 9, 2008
... and specialist services, including Independent Sector Treatment Centres, to ensure the delivery of high quality, cost-effective commissioned services. ...
Cross-border politics deny patients specialist services
ic Wales, United Kingdom - May 5, 2008
... and Welsh health commissioners are reluctant to pay for lab samples to be sent to recognised specialist centres in England for some diagnostic services. ...
Heart op is a world first for Liverpool hospital
Liverpool Daily Post, UK - May 11, 2008
The operation is a coup for the hospital in Broadgreen, as such world firsts are usually performed at specialist centres in the USA or London. ...

ic Wales
Tenovus brings cancer care closer to patients? homes
ic Wales, United Kingdom - May 11, 2008
We have developed a solution that will see mobile units and support centres rolled out across Wales over the next five years. The Tenovus mobile units will ...
Tenovus bus to provide mobile cancer treatment ic Wales
all 5 news articles »
Source: Google News

… the management of soft tissue sarcoma: Diagnosis and treatment should be given in specialist centres -
A Rydholm - BMJ: British Medical Journal, 1998 - pubmedcentral.nih.gov
... whereas no one questions that patients with bone sarcomas should be treated at
specialist tumour centres, many patients with soft tissue sarcoma (which is at ...

Variable management of soft tissue sarcoma: regional audit with implications for specialist care -
R CLASBY, K TILLING, MA SMITH, CDM FLETCHER - British Journal of Surgery, 1997 - Blackwell Synergy
... Lack of experience outside specialist centres poses difficulties for both pathologist ...
treatment and outcome for patients with soft tissue sarcoma within South ...

Effect of Reresection in Extremity Soft Tissue Sarcoma. -
JJ Lewis, D Leung, J Espat, JM Woodruff, MF … - Annals of Surgery, 2000 - annalsofsurgery.com
... with the referral of patients with rare tumors to specialist centers. ... optimal
limb-sparing multimodality treatment for soft tissue sarcoma, local recurrence ...

A randomised phase II study on neo-adjuvant chemotherapy for ?high-risk?adult soft-tissue sarcoma -
E Gortzak, A Azzarelli, J Buesa, VHC Bramwell, F … - European Journal of Cancer, 2001 - Elsevier
... J. Verweij and the EORTC Soft Tissue Bone Sarcoma ... Spain d London Regional Cancer
Centre, London, Ontario ... The Netherlands f King Faisal Specialist Hospital and ...

Prospective evaluation of soft tissue masses and sarcomas using fluorodeoxyglucose positron emission … -
JD Lucas, MJ O?Doherty, BF Cronin, PK Marsden, MA … - Br J Surg, 1999 - doi.wiley.com
... and management of these tumours may best be undertaken in specialist centres. ... Variable
management of soft tissue sarcoma: regional audit with implications for ...

Amputation for soft-tissue sarcoma -
MA Clark, JM Thomas - Lancet Oncology, 2003 - Elsevier
... 25 Soft-tissue sarcoma is at least twice as common as bone sarcoma, for which
recognition of the benefits of specialist centres is widespread. ...

… increase loco-regional control after optimal resection of soft-tissue sarcoma of the extremities? -
K Khanfir, L Alzieu, P Terrier, C Le P?choux, S … - European Journal of Cancer, 2003 - Elsevier
... Treatment strategies for soft-tissue sarcoma (STS) have gradually ... developed exclusively
in referral centres that manage ... upon in a non-specialist centre [8, 11 ...

Soft-tissue sarcomas: an update -
N de Saint Aubain Somerhausen, CDM Fletcher - European Journal of Surgical Oncology, 1999 - Elsevier
... need to achieve more consistent primary surgical management of these tumours,
preferably in specialist centres. Key words: soft-tissue; sarcoma; biopsy; grading ...

… and reresection in the management of patients with soft tissue sarcoma using conservative surgery … -
GK Zagars, MT Ballo, PWT Pisters, RE Pollock, SR … - Cancer, 2003 - doi.wiley.com
... Patients with localized soft tissue sarcoma (STS) who present to specialist centers
after undergoing apparent macroscopic total resection often have a ...

… clinical practice guidelines, multidisciplinary management and outcome of treatment for soft tissue … -
I Ray-Coquard, P Thiesse, D Ranchere-Vince, F … - Annals of Oncology, 2004 - pt.wkhealth.com
... [Context Link]. 2. Rydholm A. Improving the management of soft tissue sarcoma.
Diagnosis and treatment should be given in specialist centres. ...

Source: Google Scholar

Specialist Centres Should Deal With All Soft Tissue Sarcomas
Soft tissue sarcomas---rare tumours of the connective tissue---should be treated at the few centres which see most cases, in order to give patients the best chance of good outcomes, concludes an analysis of sarcoma management in Florida, published in the Annals of Surgery last month.

"STS [soft tissue sarcomas] are rare. This paucity leaves most health care institutions with low case volumes and outdated or inadequate resources, which impede the ability to offer optimal treatment of these rare and often complicated tumours," the authors explain.
Using an analysis of a large population-based state cancer registry in Florida, the Juan Gutierrez and colleagues tested the hypothesis that soft tissue sarcomas are better treated at institutions with higher volumes of cases. They used the Florida cancer data system, a prospective database of all cancer cases in the state of Florida since 1981, to identify all records of soft tissue sarcomas up to 2001. A total of 6259 cases were extracted and, after duplicates were removed, the researchers arrived at a total of 5564 unique cases. A final study sample of 4205 cases was created by excluding individuals who had non-surgical treatments.

Next, the researchers looked at the medical facilities where each person's treatment was done. A total of 256 institutions in Florida performed at least one resection of a soft tissue sarcoma between 1981 and 2001; these were grouped into percentile ranges by surgical procedure volume. Of 4673 surgical procedures recorded (including repeat procedures, which were excluded from the main analysis), 7 institutions performed 1504 cases (32.2%) and were classified as high volume centres. The remaining two thirds of institutions did 3169 cases (67.8% of the total) and were classed as low volume. "Our analysis of 20 years' surgical management of STS in Florida…[showed that] volumes in 213 facilities amounted to less than 1 case per year and less than 2 cases per year were managed at an additional 79 health care institutions," reported the authors.

Patients at high volume centres were generally younger, with a higher proportion of women, were more likely to have high-grade tumours and were more likely to receive radiation therapy and chemotherapy. When the authors looked at outcomes, they found that 30-day mortality rates were twice as high in low volume centres than in high volume institutions; there was a similar disparity with the 90-day mortality rate. Median 5-year and 10-year survival was significantly better for patients treated at high volume centres (40 months versus 37 months); however, survival of patients with extremity tumours was equal among the two groups of institutions. There was a slight selection bias in favour of the low volume centres because tumours managed at high volume places were higher grade and larger in size but despite this, higher volume centres achieved superior outcomes in patients with high grade lesions and those with tumours over 10 cm in size.
In an additional analysis, the researchers examined outcomes from treatment of extremity tumours alone to establish whether the volume of surgeries done at a centre affected the likelihood of patients keeping their limbs. A total of 1937 extremity tumours were analysed. At high volume centres, 90.6% of procedures for these tumours were limb sparing operations compared with 86.2% at low volume centres, suggesting that physicians at low-volume centres were more likely to resort to amputation to protect the patient's survival chances.

"This analysis reveals a direct correlation between hospital surgical volume and both short-term and long-term treatment outcomes for STS. While the observations reported here require confirmation with additional independent data sets they argue persuasively for exclusive referral of patients with STS to high volume specialised centres for optimal treatment, survival, and functional outcomes," conclude the authors.

Should soft tissue sarcomas be treated at high volume centres" An analysis of 4205 patients Juan Gutierrez, Eduardo Perez, Frederick Moffat, Alan Livingstone, Dido Fransceschi, and Leonidas Koniaris Annals of Surgery 2007; 245:952-58

Source: Corinne Hall
European School of Oncology
 
 
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