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Recent News and Articles on the Keywords: lisa esposito + hbns-editor@cfah.org + center  Related to the article below (Last Update: 5/5/2008)

Antioxidant users don't live longer, analysis of studies concludes
innovations report, Germany - Apr 18, 2008
Health Behavior News Service: Lisa Esposito at (202) 387-2829 or hbns-editor@cfah.org. Bjelakovic G, et al. Antioxidant supplements for prevention of ...
Source: Google News

Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans Role of … -
K Esposito, F Nappo, R Marfella, G Giugliano, F … - Circulation, 2002 - Am Heart Assoc
Methods and Results? Plasma glucose levels were acutely raised in 20 control
and 15 IGT subjects and maintained at 15 mmol/L for 5 hours while endogenous
insulin secretion was blocked with octreotide. In control subjects, plasma ...

Potential virulence determinants in terminal regions of variola smallpox virus genome -
RF Massung, JJ Esposito, L Liu, J Qi, TR Utterback … - Nature, 1993 - nature.com
* Division of Viral and Rickettsial Diseases, National Center for Infectious
Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333,
USA ? National Institute of Neurological Disorders and Stroke, National ...

Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Circulating Adhesion Molecules and … -
… Piconi, R Assaloni, R Da Ros, A Maier, K Esposito … - Diabetes, 2004 - Am Diabetes Assoc
Adhesion molecules, particularly intracellular adhesion molecule (ICAM)-1,
vascular cell adhesion molecule (VCAM)-1, and E-selectin, have been associated
with cardiovascular disease. Elevated levels of these molecules have been ...

Effect of Atorvastatin and Irbesartan, Alone and in Combination, on Postprandial Endothelial … -
… Da Ros, A Maier, L Piconi, L Quagliaro, K Esposito … - Circulation, 2005 - Am Heart Assoc
Methods and Results? Twenty type 2 diabetic patients ate 3 different test
meals: a high-fat meal, 75 g glucose alone, and a high-fat meal plus glucose.
Glycemia, triglyceridemia, endothelial function, nitrotyrosine, C-reactive ...

Targeted Inhibition of Wound-Induced PAI-1 Expression Alters Migration and Differentiation in Human … -
… MG Steiner, I Pagan-Charry, D Esposito, B Chin, KM … - Experimental Cell Research, 2000 - Elsevier
Targeted Inhibition of Wound-Induced PAI-1 Expression Alters ... Migration and
Differentiation in Human Epidermal Keratinocytes ... Fangqin Li,* John
Goncalves,* Kerri Faughnan,* Melissa G. Steiner,* Iraida Pagan-Charry,* ...

Reduction in Mitochondrial Superoxide Dismutase Modulates Alzheimer's Disease-Like Pathology and … -
L Esposito, J Raber, L Kekonius, F Yan, GQ Yu, N … - Journal of Neuroscience, 2006 - Soc Neuroscience
Alzheimer's disease (AD) is associated with accumulations of amyloid- (A )
peptides, oxidative damage, mitochondrial dysfunction, neurodegeneration, and
dementia. The mitochondrial antioxidant manganese superoxide dismutase-2 ...

Efficacy, tolerability, and effects on quality of life of inhaled salmeterol and oral theophylline … -
G Di Lorenzo, G Morici, A Drago, ME Pellitteri, P … - Clinical Therapeutics, 1998 - Elsevier
The aims of management in mild-to-mod- erate stable chronic obstructive
pulmonary disease (COPD) are to improve symptoms and quality of life (QOL),
reduce decline in lung function, prevent and treat com- plications, ...

Interventions for replacing missing teeth: treatment of perimplantitis -
M Esposito, MG Grusovin, P Coulthard, HV … - Australian Dental Journal, 2007 - Blackwell Synergy
Abstract Background: One of the key factors for the long-term success of oral
implants is the maintenance of healthy tissues around them. Bacterial plaque
accumulation induces inflammatory changes in the soft tissues surrounding ...

Acute Hyperglycemia Induces Nitrotyrosine Formation and Apoptosis in Perfused Heart From Rat -
A Ceriello, L Quagliaro, MD'Amico, C Di Filippo, R … - Diabetes, 2002 - Am Diabetes Assoc
This study investigated coronary perfusion pressure, nitric oxide (NO) and
superoxide production, nitrotyrosine (NT) formation, and cardiac cell apoptosis
in isolated hearts perfused with high glucose concentration. Coronary ...

Serum Levels of Interleukin-18--a Potential Marker of Cardiovascular Death--Could Be Determined by … -
A Kretowski, I Kinalska, K Esposito, F Nappo, R … - Circulation, 2003 - Am Heart Assoc
In our recent study (Kretowski et al, unpublished data, 2002), we observed that
in newly diagnosed subjects with type 1 diabetes, fasting baseline serum levels
of IL-18 were increased in comparison with healthy controls, and the degree ...

Source: Google Scholar

Contact: Lisa Esposito
hbns-editor@cfah.org
Center for the Advancement of Health

Advice, devices ineffective in preventing worker back pain

Back pain is the number one cause of worker-compensation complaints, second only to the common cold in causing lost workdays. Consequently, employers and regulators have pushed training programs to teach specific lifting methods, and some recommend or require the use of assistive devices such as hoists for hospital workers. However, a new review of the research on lifting advice and handling devices has found that they do not prevent work-related back pain.

“According to the studies we have so far, it seems that this is not effective,” said lead author Kari-Pekka Martimo, of the Finnish Institute of Occupational Health in Helsinki. He and his colleagues examined data from more than 18,000 employees in 11 studies. Some studies looked at advice or assistive devices alone and some looked at combining both, but the combinations did not prove effective either.

The review appears in the latest issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research. Systematic reviews draw evidence-based conclusions about medical practice after considering both the content and quality of existing medical trials on a topic.

The advice and devices did not prevent back pain or reduce disability claims or sick leave.

According to Martimo, one explanation for the negative findings could be that “safer” lifting techniques do not really exist — so teaching particular tactics would be unlikely to help. “Another possibility is that elevated risk for back pain might not be related to lifting or moving heavy objects themselves, but to other aspects of work,” he said. High stress, for example, might link jobs that require lifting to back pain, rather than the lifting itself.

Alternatively, it could be that the teaching is the problem — and that workers do not actually adopt better habits. However, the studies looked at many different training methods and did not find any to have a particular advantage. “I don’t think it’s lack of adequate teaching methods,” Martimo said. One complication of considering that there is a “correct” lifting technique that employees should adopt is that “when an employee has back pain, there’s a tendency to blame the victim because he didn’t [use the techniques or devices] correctly.”

“This study confirms that much of what is happening at the workplace is well-intentioned but probably pointless,” said Christopher Maher, associate professor of physiotherapy at the University of Sydney in Australia. “We had a pretty good idea that this was the case but this study really does confirm that we need to take a fresh look at the problem,” said Maher, who was not involved with the study.

“The frustrating thing is that government bodies and employers concentrate on things that do not work, [such as] back belts, education, lifting devices, workplace redesign and no-lift policies, and ignore the only known effective intervention — exercise,” Maher added. “We also know that exercise has health benefits beyond prevention of back pain, so you are getting two health benefits (or more) for the price of one.”

Martino concluded, “We need more studies and evidence on the chain of events between certain jobs and an elevated risk of back pain. We do not know enough about that chain yet.”

###

By Maia Szalavitz, Contributing Writer Health Behavior News Service

FOR MORE INFORMATION: Health Behavior News Service: Lisa Esposito at (202) 387-2829 or hbns-editor@cfah.org.

Martimo KP, et al. Manual material handling advice and assistive devices for preventing and treating back pain in workers (Review). Cochrane Database of Systematic Reviews 2007, Issue 3.

The Cochrane Collaboration is an international nonprofit, independent organization that produces and disseminates systematic reviews of health care interventions and promotes the search for evidence in the form of clinical trials and other studies of interventions. Visit http://www.cochrane.org for more information.
 
 
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