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Recent News and Articles on the Keywords: false positive + false-positive cancer + cancer  Related to the article below (Last Update: 7/1/2008)

Construction of a cancer-perturbed protein-protein interaction ...
7thSpace Interactive (press release), NY -
Next, we applied a nonlinear stochastic model, maximum likelihood parameter estimation, and Akaike Information Criteria (AIC) to eliminate false-positive ...

Business Wire (press release)
Provista Life Sciences and International Health Technology ...
Business Wire (press release), CA -
The BT Test, a new blood test to aid healthcare providers in early breast cancer detection, will be provided through IHT?s women?s clinic for breast health, ...
Avoiding a False Positive on Your Mammogram
U.S. News & World Report, DC - Jun 11, 2008
They also may detect "false positive" abnormalities?in all women regardless of their breast density?that look suspiciously like cancer but are really benign ...
Q&A with Dr Thomas Stuttaford on prostate cancer (part 2)
Times Online, UK - Jun 18, 2008
The clinical importance of false positives has been, in my opinion, grossly exaggerated for medico political reasons. Nobody wants to have a false positive ...
Gene test gives early alert for breast cancer
guardian.co.uk, UK - Jun 25, 2008
... clear-cut and that significant numbers of women are given a false positive result, causing anxiety and in some cases leading to unnecessary treatment. ...

dBTechno
Ovarian Cancer Symptoms Plus Blood Test Aid Early Detection
MedPage Today, NJ - Jun 23, 2008
The false positive rate among high-risk women without cancer was 11.8% with the symptom index but 0% if positive results were required on both screening ...
Ovarian symptoms check with blood test improves detection, study finds CBC.ca
Breakthrough in fight against ovarian cancer NECN
Researchers say they've discovered a breakthrough in detecting ... WZZM
all 55 news articles »
18 F-FDG Uptake in Reactive Neck Lymph Nodes of Oral Cancer ...
Journal of Nuclear Medicine (subscription) - Jun 27, 2008
Reactive lymphadenopathy is well known as a principal cause of false-positive findings on PET/CT for nodal staging. We investigated the reactive lymph nodes ...
Asymptomatic anal HPV infection more common than thought in ...
Aidsmap, UK -
They also acknowledge the possibility of false-positive results; that DNA might have been detected from the skin surface without true infection; ...
When a Mammogram Isn't Enough
Wall Street Journal - Jun 23, 2008
One downside: the risk that MRI and ultrasound screenings can produce many false positives, creating needless anxiety in some patients. After the cancer ...
Polygenic Analysis May Aid Breast Cancer Diagnosis
GenomeWeb News (subscription), NY - Jun 26, 2008
Still, they noted that ?[m]ost reported genetic associations have been false positive results and would be worthless for risk prediction. ...
Source: Google News

Ten-Year Risk of False Positive Screening Mammograms and Clinical Breast Examinations -
JG Elmore, MB Barton, VM Moceri, S Polk, PJ Arena, … - New England Journal of Medicine, 1998 - content.nejm.org
... False Positives with Mammograms and Breast Exams. JWatch Women's Health 1998:
5-5 [Full Text]; (1998). False Positive Results in Breast Cancer Screening. ...

Hepatic metastases from colorectal cancer: detection and false-positive findings with helical CT … -
P Soyer, DA Bluemke, RH Hruban, JV Sitzmann, EK … - Radiology, 1994 - ncbi.nlm.nih.gov
Click here to read Hepatic metastases from colorectal cancer: detection and
false-positive findings with helical CT during arterial portography. ...

Factors associated with false-positive staging of lung cancer by positron emission tomography -
PF Roberts, DM Follette, MD Derek von Haag, JA … - The Annals of Thoracic Surgery, 2000 - Soc Thorac Surgeons
... role in staging lung cancer. At distant sites, false-positive PET findings are less
common than in the mediastinum, resulting in a positive predictive value of ...

… of false positive findings of mammography in breast cancer screening: analysis of false positive -
E Lidbrink, J Elfving, J Frisell, E Jonsson - BMJ, 1996 - ncbi.nlm.nih.gov
... Neglected aspects of false positive findings of mammography in breast cancer screening:
analysis of false positive cases from the Stockholm trial. ...

[CITATION] Human papillomavirus is a necessary cause of invasive cervical cancer worldwide -
JMM Walboomers, MV Jacobs, MM Manos, FX Bosch, JA … - The Journal of Pathology, 1999
... biopsies from patients with cervical cancer were HPV ... products of CPI/II PCR- positive
specimens were ... precautions were taken to prevent false- positive results. ...

Use of proteomic patterns in serum to identify ovarian cancer -
EF Petricoin, AM Ardekani, BA Hitt, PJ Levine, VA … - The Lancet, 2002 - Elsevier
... pelvic disease? circumstances in which false positive CA125 results ... 2 , 3 , 4 and
5 A positive-predictive value ... where the incidence of ovarian cancer in the ...

Effect of False-Positive Mammograms on Interval Breast Cancer Screening in a Health Maintenance … -
ML Burman, SH Taplin, DF Herta, JG Elmore - Annals of Internal Medicine, 1999 - annals.highwire.org
... False-positive mammograms were defined as positive mammograms in women without
a diagnosis of breast cancer during the subsequent 12 months. ...

… Evaluating Para-aortic Nodal Metastasis in Locally Advanced Cervical Cancer Before Surgical Staging … -
PG Rose, LP Adler, M Rodriguez, PF Faulhaber, FW … - Journal of Clinical Oncology, 1999 - jcojournal.org
... Six of eight patients with positive para-aortic ... had only one microscopic focus of
metastatic cancer. Two patients were identified as false-positive PET scans ...

Psychiatric morbidity associated with screening for breast cancer.
R Ellman, N Angeli, A Christians, S Moss, J … - Br J Cancer, 1989 - ncbi.nlm.nih.gov
... further investigation of a positive screening result ... screened women, women with false
positive screening results ... diagnosis, newly diagnosed cancer patients and ...

Technetium-99m-sestamibi prone scintimammography to detect primary breast cancer and axillary lymph … -
R Taillefer - Journal of Nuclear Medicine, 1995 - Soc Nuclear Med
... for detecting primary breast cancer was 91.5% (43 true-positive, 4 false-negative)
and the specificity was 94.4% (17 true-negative, 1 false-positive). ...

Source: Google Scholar

Survey Determines Impact of False-positive Cancer Tests

Copenhagen, Denmark – July 19, 2007 - According to a new study in Value in Health, women coping with the strain of being mistakenly diagnosed with breast cancer have not been adequately studied in the past. The focus of the study is a new survey that accurately assesses the negative effects of false diagnosis and provides useful information to health care practitioners and researchers.

“We know that having a false alarm at a breast cancer screening causes significant negative psychological harm,” says Dr. John Brodersen, co-author of the study. “Unfortunately, previous studies of the long-term psychological consequences of these false alarms have used inadequate measures.”

The survey, developed by Brodersen and his colleagues, focuses on six psychosocial dimensions; anxiety, behavioral impact, sense of dejection, impact on sleep, breast examination and sexuality. The survey showed that women who had an abnormal screening mammography later confirmed to be false-positive were negatively influenced in all six categories.

“This is an urgent issue to be addressed, because one-in-four women following the European Union-recommended biannual breast cancer screening program over a 20-year period will experience a false-positive screening mammogram,” says Brodersen. “Thousands of women experience false-positive screening results.

Therefore, women should be better informed both before breast cancer screening and during the screening process. This should include a discussion about the implications of a false-positive result, as well as the benefits of early detection of breast cancer.”

_________________________________________________________________
This study is published in the July/August issue of Value in Health. Media wishing to receive a PDF of this article may contact medicalnews@bos.blackwellpublishing.net.

John Brodersen, M.D., GP, Ph.D. is senior researcher in the Department of Research Unit of General Practice at the Institute of Public Health at the University of Copenhagen. He can be reached for questions at j.brodersen@gpmed.ku.dk.

Value in Health is a multidisciplinary peer-reviewed journal reporting on evaluations of medical technologies including pharmaceuticals, biologics, devices, procedures, and other health care interventions. It is also a sounding board for the discussion of health policy issues related to health economics and outcomes studies associated with all medical technologies. For more information, please visit www.blackwellpublishing.com/vhe.

Wiley-Blackwell was formed in February 2007 as a result of the merger between Blackwell Publishing Ltd. and John Wiley & Sons, Inc.'s Scientific, Technical, and Medical business. Together, the companies have created a global publishing business with deep strength in every major academic and professional field. Wiley-Blackwell publishes approximately 1,250 scholarly peer-reviewed journals and an extensive collection of books with global appeal. For more information on Wiley-Blackwell, please visit www.blackwellpublishing.com or http://interscience.wiley.com.

###

Media Contact

Sean Wagner
Public Relations Specialist
350 Main St.

Malden, MA 02148
United States
781-388-8550 (phone)
781-338-8550 (fax)
swagner@bos.blackwellpublishing.com

 
 
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