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Recent News and Articles on the Keywords: glaucoma drug + glaucoma drugs + glaucoma  Related to the article below (Last Update: 5/5/2008)

Biovitrum Presents Detailed Results From Clinical Neuropathic Pain ...
ABN Newswire (press release), Australia - Apr 29, 2008
One study involved the treatment of glaucoma (5-HT2A receptor antagonist) and the other neuropathic pain in diabetes patients (pH selective A2A receptor ...STO:BVT
Few Side Effects From Long-Term Use of Combination Latanoprost ...
DG News - Apr 30, 2008
The spectrum of side effects from other ocular hypotensive drugs has led scores of patients with glaucoma to stop using their medications within the first ...

Boston Globe
Novartis set to purchase 77% of Alcon for $39b
Boston Globe, United States - Apr 7, 2008
... and treatments for glaucoma. Novartis would also lessen its reliance on pharmaceuticals as new drugs face delays and sales of the hypertension drug ...PINK:NVSEF - VTX:NESN
In marijuana debate, both sides can point to the science
Minneapolis Star Tribune, MN - Apr 20, 2008
Scientists have also tested marijuana's active ingredients on other conditions, such as glaucoma and multiple sclerosis. Results have been mixed and ...
Lpath Submits Investigational New Drug Application for iSONEP(TM)
CNNMoney.com - Apr 14, 2008
... in the treatment of diabetic retinopathy, dry AMD, and uveitis, and in the prevention of scar formation associated with many glaucoma-related surgeries. ...OTC:LPTN
Preservative-Free Travoprost Significantly Better on Ocular ...
DG News - Apr 30, 2008
Ocular surface disease and ocular hyperaemia are common side effects of ocular hypotensive drugs, causing many glaucoma patients to become noncompliant with ...
NTSB: Drug, Alcohol Use by Bay Pilot
The Associated Press - Apr 9, 2008
_Alphagan, used to treat glaucoma. Side effects can include tiredness or blurred vision. _Imitrex, a migraine drug. Side effects can include dizziness or ...

eFluxMedia
NTSB Blames Pilot?s Medication and Alcohol Use for SF Oil Spill
eFluxMedia - Apr 10, 2008
Despite a series of illnesses including glaucoma, depression, kidney stones, migraines, pancreatitis and, most recently, sleep apnea, for which he was ...
World Ophthalmic Pharmaceutical Drugs Market to Reach $12.86 ...
Emediawire (press release), WA - Apr 24, 2008
... offer abundant opportunities for drug research initiatives, include Cataracts, Myopia, diabetic retinopathy, Dry AMD, and Neuroprotection in glaucoma, ...GLBL
Behind Novartis' Eye-Popping Buyout
BusinessWeek - Apr 8, 2008
... whose business spans prescription drugs for eye diseases such as glaucoma, over-the-counter products such as Opti-Free contact lens solutions, ...
Source: Google News

Bimatoprost and Travoprost A Review of Recent Studies of Two New Glaucoma Drugs -
DL Eisenberg, CB Toris, CB Camras - Survey of Ophthalmology, 2002 - Elsevier
... study included 573 patients with open-angle, exfoliation, pigmentary glaucoma, or
ocular ... for morning use while the timolol group used active drug twice daily. ...

Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma. -
A Harris, GL Spaeth, RC Sergott, LJ Katz, LB … - Am J Ophthalmol, 1995 - ncbi.nlm.nih.gov
... these drugs also alter, either directly or indirectly, orbital hemodynamics is
potentially of great importance for patients with normal-tension glaucoma who ...

Trabeculectomy with simultaneous topical application of mitomycin-C in refractory glaucoma.
CW Chen, HT Huang, JS Bair, CC Lee - J Ocul Pharmacol, 1990 - ncbi.nlm.nih.gov
1990 Fall;6(3):175-82. Trabeculectomy with simultaneous topical application of
mitomycin-C in refractory glaucoma. Chen CW, Huang HT, Bair JS, Lee CC. ...

Intraoperative mitomycin versus postoperative 5-fluorouracil in high-risk glaucoma filtering surgery … -
GL Skuta, CC Beeson, EJ Higginbotham, PR Lichter, … - Ophthalmology, 1992 - ncbi.nlm.nih.gov
... filtering site in 20 eyes at high risk for failure of glaucoma filtering surgery ...
Drug-induced corneal epithelial defects were seen in nine 5-FU-treated eyes and ...

Effects of topical glaucoma drugs on fistulized rabbit conjunctiva. -
TL Young, EJ Higginbotham, XL Zou, MD Farber - Ophthalmology, 1990 - ncbi.nlm.nih.gov
Ophthalmology. 1990 Nov;97(11):1423-7. Effects of topical glaucoma drugs on fistulized
rabbit conjunctiva. Young TL, Higginbotham EJ, Zou XL, Farber MD. ...

Intraocular Pressure?Lowering Effects of All Commonly Used Glaucoma Drugs A Meta-analysis of … -
R van der Valk, CAB Webers, JSAG Schouten, MP … - Ophthalmology, 2005 - Elsevier
... Original Article. Intraocular Pressure?Lowering Effects of All Commonly Used
Glaucoma Drugs A Meta-analysis of Randomized Clinical Trials. ...

… of inflammatory membrane markers by conjunctival cells in chronically treated patients with glaucoma
C Baudouin, C Garcher, N Haouat, A Bron, P Gastaud - Ophthalmology, 1994 - ncbi.nlm.nih.gov
... conjunctival cells). Results were not related to a specific treatment or
combination of anti-glaucoma drugs. However, the proportion ...

[PDF] Medical management of glaucoma -
WL Alward - N. Engl. J. Med, 1998 - ecu.edu
... therapy. Timolol was released in the United States in 1978 and quickly became
the most popular drug for the treatment of glaucoma. When ...
-

Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: a six-month … -
CB Camras - Ophthalmology, 1996 - ncbi.nlm.nih.gov
Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma:
a six-month masked, multicenter trial in the United States. ...

… -masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. The … -
P Watson, J Stjernschantz - Ophthalmology, 1996 - ncbi.nlm.nih.gov
... with 0.5% timolol administered twice daily in patients with open-angle glaucoma
or ocular ... No upward drift in IOP occurred with either drug during the treatment ...

Source: Google Scholar

Early trial suggests promise for glaucoma drug

Last Updated: 2007-07-18 13:44:37 -0400 (Reuters Health)

CHICAGO - An experimental drug to treat glaucoma appears promising based upon the results of early-stage trials sponsored by the drug's maker Alcon Inc., analysts said on Wednesday.

The results of the phase II study of anecortave acetate in glaucoma were presented at the World Glaucoma Congress in Singapore.

Glaucoma refers to eye diseases that affect the optic nerve and cause vision loss. Most of these diseases cause high pressure inside the eye, called intraocular pressure (IOP). Elevated IOP is the most important risk factor for the development of glaucoma.

Despite a high dropout rate in the trial, anecortave acetate "showed strong potential for sustained reduction of IOP," Mike Weinstein, an analyst with JP Morgan, wrote in a research note.

While statistical significance was not reached in the groups that received lower doses of the drug, significance was achieved in the group that received the drug at the highest dose.

Alcon, an eye-care products maker, said an additional larger study would be needed for approval and estimated it would file a new drug application with U.S. regulators in 2009 versus its earlier estimate of 2008.

(Reporting by Debra Sherman, editing by Jeffrey Benkoe)

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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