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Recent News and Articles on the Keywords: trick + revealed + scientists  Related to the article below (Last Update: 8/5/2008)


TVNZ
Chemical discovery on Mars stumps Phoenix team
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ReutersVideo
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Scientists from the Centers for Disease Control and Prevention reported Saturday that 56300 people nationwide became infected with HIV in 2006, ...
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Generic phishing scams that try to trick people into typing their usernames and passwords at spoofed Web pages are typically mass-e-mailed indiscriminately. ...
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U-turn as lab accepts scientist caught meningitis at work
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Source: Google News

[BOOK] The Secret Life of Lobsters: How Fishermen and Scientists Are Unraveling the Mysteries of Our … -
T Corson - 2004 - books.google.com
... Other graves revealed that the ocean wasn't the ... a century the relationship between
scientists and lobstermen in ... of coor- dinates to the scientist?numbers he ...

[BOOK] The Secret History of Emotion: From Aristotle's Rhetoric to Modern Brain Science
DM Gross - 2006 - books.google.com
... ofCongress Cataloging-in-Publication Data Gross, Daniel M., 1965- The secret history
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[BOOK] Artful Science: Enlightenment, Entertainment, and the Eclipse of Visual Education
BM Stafford - 1994 - books.google.com
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Science is neither sacred nor a confidence trick
S Haack - Foundations of Science, 1995 - Springer
... SCIENCE IS NEITHER SACRED NOR A CONFIDENCE TRICK* ... avoid the need for discretion -
as is revealed by the ... is there any guarantee that, as science proceeds, it ...

The Unaccountable Element in Science
M Polanyi - Philosophy, 1962 - JSTOR
... tree or a table, we are performing a secret trick which is unlikely ever to be revealed
to our ... to have occurred, have been widely accepted among scientists. ...

[BOOK] Uncertainty and Quality in Science for Policy -
SO Funtowicz, JR Ravetz - 1990 - books.google.com
... A new role for scientists will involve the management of these crucial uncertainties;
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[BOOK] Investigating Science with Dinosaurs
CA Munsart - 1993 - books.google.com
... the secret behind the mystery is revealed, the wonder ... Robert Scott Root-Bernstein's"
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A low-cost high-impact computer science show for family audiences -
T Bell - Computer Science Conference, 2000. ACSC 2000. 23rd …, 2000 - ieeexplore.ieee.org
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[BOOK] The Biology of Doom: The History of America's Secret Germ Warfare Project
E Regis, E Regis - 2000 - books.google.com
... Beyond the narrow confines of the US Army, the world of science was full of pro ... that
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The mind's best trick: how we experience conscious will -
DM Wegner - Trends in Cognitive Sciences, 2003 - Elsevier
... the popular explanation, investigations by scientists such as ... devices between hands
and tables) revealed that the ... of conscious will is a marvelous trick of the ...

Source: Google Scholar
 

Toxoplasmosis infection trick revealed by scientists

Toxoplasmosis is a parasitic disease, primarily carried by cats. It is transmitted to humans by eating undercooked meat or through contact with cat faeces. It is particularly dangerous for pregnant women, whose foetuses can be infected via the placenta, and those with a weakened immune system, such as people infected with HIV. In severe cases, toxoplasmosis can cause damage to the brain and eyes, and even death

Now researchers from London and Geneva have determined, for the first time, the atomic structure of a key protein which is released onto the surface of the parasite just before it invades host cells in the human body. They found that the protein known as TgMIC1 binds to certain sugars on the surface of the host cell, assisting the parasite to stick to, and then enter the human cell.

Using a novel carbohydrate microarray the team were able to identify the precise sugars to which the parasite protein binds. Following this the team used a combination of NMR spectroscopy and cellular studies to characterise the behaviour and interactions of the parasite protein and host cell sugars. This means that the team have a more detailed picture than ever before of exactly how the parasite recognises and attacks host cells in the body.

Article continues below and (thank you)

 

Professor Steve Matthews from Imperial College London’s Division of Molecular Biosciences, one of the paper’s authors, explains the significance of the research, saying: "Understanding the fundamental, atomic-level detail of how diseases like toxoplasmosis pick out and invade host cells in the human body is vital if we want to fight these diseases effectively.

"Now that we understand that it’s a key interaction between a protein on the parasite’s surface and sugars on the human cell which lead to the cell’s invasion, there is potential to develop therapeutics that are targeted at disrupting this mechanism, therefore thwarting infection."

Toxoplasma gondii, the parasite that causes toxoplasmosis, is one of the world’s most common parasites. Around a quarter to half of the world’s population is thought to be infected, and around 1% of people in the UK catch toxoplasmosis each year. In the majority of cases, those affected don’t have any symptoms. But for those with weakened immune systems, and unborn babies, toxoplasmosis can cause very serious health problems.

 
 
 
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