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Recent News and Articles on the Keywords: brugada syndrome + brugada syndrome: + brugada  Related to the article below (Last Update: 8/5/2008)

Heart Healthy: Preventive Medicine 2008
Medscape (subscription) -
... a hereditary cause without structural disease -- for example, long or short QT syndrome, catecholaminergic ventricular tachycardia, or Brugada syndrome. ...
Woman crosses bridges for charity
Buckinhamshire Free Press, UK - Jul 23, 2008
The Manchester University student became involved with the charity when she and her dad Peter were diagnosed with Brugada Syndrome last year. ...
Ont. introduces guidelines for coroners, pathologists
Canada.com, Canada - Jul 29, 2008
They include Long QT syndrome, Short QT syndrome, Brugada syndrome and CPVT. But because the flaw is located in a faulty gene, routine autopsies can't ...
Grieving parents walk for charity
Essex Echo, UK - Jul 25, 2008
... Billericay, became involved with the charity when they lost their son, James from an undiagnosed cardiac illness ? Brugada Syndrome ? in 2005. ...
Heart Disease Specialists Meet Spanish Footballers To Develop ...
Medical News Today (press release), UK - Jul 17, 2008
Several ion channel abnormalities have been identified that are known to increase the risk of sudden cardiac arrest, including long QT syndrome and Brugada ...
Source: Google News

… sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report -
P Brugada, J Brugada - Journal of the American College of Cardiology, 1992 - Am Coll Cardio Found
... Rodriguez Tpeak-Tend and Tpeak-Tend Dispersion as Risk Factors for Ventricular
Tachycardia/Ventricular Fibrillation in Patients With the Brugada Syndrome J. Am ...

Brugada Syndrome: Report of the Second Consensus Conference Endorsed by the Heart Rhythm Society and … -
… , P Brugada, M Borggrefe, J Brugada, R Brugada, D … - Circulation, 2005 - Am Heart Assoc
... Special Report. Brugada Syndrome: Report of the Second Consensus Conference. ...
Bottom, Twelve-lead ECGs in a patient with Brugada syndrome. ...

Proposed Diagnostic Criteria for the Brugada Syndrome Consensus Report -
… , M Borggrefe, J Brugada, R Brugada, P Brugada, D … - Circulation, 2002 - Am Heart Assoc
... Mini-Review: Current Perspective. Proposed Diagnostic Criteria for the Brugada Syndrome.
Consensus Report. ... 27. The Diagnosis of Brugada Syndrome. ...

… Responsible for the Electrocardiographic Phenotype of the Brugada Syndrome Are Temperature Dependent -
… DV Nesterenko, VV Nesterenko, J Brugada, R Brugada … - Circulation Research, 1999 - Am Heart Assoc
... Cellular Biology. Ionic Mechanisms Responsible for the Electrocardiographic
Phenotype of the Brugada Syndrome Are Temperature Dependent. ...

… and antiarrhythmic drug modulation of STsegment elevation in patients with Brugada syndrome -
T Miyazaki, H Mitamura, S Miyoshi, K Soejima, Y … - Journal of the American College of Cardiology, 1996 - Am Coll Cardio Found
... Autonomic and antiarrhythmic drug modulation of ST segment elevation in
patients with Brugada syndrome. T Miyazaki, H Mitamura, S ...

… Death in Individuals With the Electrocardiographic Pattern of Brugada Syndrome and No Previous … -
J Brugada, R Brugada, P Brugada - Circulation, 2003 - Am Heart Assoc
... Determinants of Sudden Cardiac Death in Individuals With the Electrocardiographic
Pattern of Brugada Syndrome and No Previous Cardiac Arrest. ...

… basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome -
… , K Nademanee, R Brugada, J Brugada, G Veerakul, H … - Human Molecular Genetics, 2002 - Oxford Univ Press
... Genetic and biophysical basis of sudden unexplained nocturnal death syndrome
(SUNDS), a disease allelic to Brugada syndrome. Matteo ...

Brugada Syndrome A Decade of Progress -
C Antzelevitch, P Brugada, J Brugada, R Brugada, W … - Circulation Research, 2002 - Am Heart Assoc
... Inc. MiniReview. Brugada Syndrome. A Decade of Progress. C ... syndrome. 33 Only 20%
of Brugada syndrome cases have been linked to SCN5A mutations. A ...

Brugada syndrome: 1992-2002 A historical perspective -
C Antzelevitch, P Brugada, J Brugada, R Brugada, … - Journal of the American College of Cardiology, 2003 - Am Coll Cardio Found
... Brugada syndrome: 1992?2002. A historical perspective. ... Evolution of a new clinical
entity responsible for sudden cardiac death: Brugada syndrome. ...

Proposed Diagnostic Criteria for the Brugada Syndrome -
… , M Borggrefe, J Brugada, R Brugada, P Brugada, D … - European Heart Journal, 2002 - Eur Soc Cardiology
... Consensus Report Proposed Diagnostic Criteria for the Brugada Syndrome ... What are the
proper diagnostic criteria to be used in identifying Brugada syndrome? ...

Source: Google Scholar
 

Brugada Syndrome

Brugada syndrome is an abnormality of the heart cells that disrupts the electrical activity in the heart and can cause life-threatening heart rhythms.

Symptoms

Because Brugada syndrome disturbs the heart's rhythm, blood is not pumped effectively through the body. Symptoms can include:

  • Fainting as a result of the brain not receiving enough blood
  • A chaotic, uncoordinated electrical pattern (called ventricular fibrillation). In this situation, the heart quivers and stops pumping blood. Sudden death usually occurs unless the heart is electrically shocked back into a normal pattern by a defibrillator.

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Causes and Risk Factors

Electrical signals in the heart coordinate when and how often the heart beats. Electrically charged elements flow in and out of the heart cells through tiny pores called channels. They control the flow of charged particles through the heart's cells, and thereby the electrical activity of the heart. A defect in the channels causes periods of abnormal electrical activity.

In many cases, the cause of Brugada syndrome is not known. Genetics may play a role in some families.

Brugada syndrome often occurs in young adults.

Diagnosis

Brugada syndrome can be identified on an electrocardiogram (ECG). An ECG can be abnormal without the patient having dangerous heart rhythm irregularities - a condition called a Brugada sign. If heartbeat irregularities are also present, it is called Brugada syndrome.

A doctor may also recommend:

  • Continuous monitoring of the heart's electrical activity with a Holter monitor, - a device in which electrodes are attached to the chest and connected to a portable recorder. The Holter monitor allows the wearer to perform normal activities while the heart is being monitored during a 24-hour period.
  • Electrophysiologic studies. For these studies, the doctor threads electrodes attached to a long, thin tube (catheter) through a vein in the arm or leg and into the heart. The electrodes record how electrical impulses spread through the heart.
Treatment

Treatment depends on the risk of developing an abnormal heart rhythm (arrhythmia). Risk factors for arrhythmia include:

  • A history of relatives who died young as a result of sudden heart attacks
  • Having had heart rhythm problems
  • Having a history of fainting spells
People who are at high risk of sudden death usually undergo surgery to implant a defibrillator. The defibrillator is a small device that is inserted inside the chest. It continuously tracks the heart's rhythm and gives precise electrical shocks whenever they are needed to control abnormal, racing heartbeats.
 
 
 
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