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Recent News and Articles on the Keywords: disease + heart + 0.27  Related to the article below (Last Update: 8/5/2008)

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Seeking Alpha, NY - Jul 21, 2008
Dow -0.27% to 11466. S&P -0.18% to 1258. Nasdaq -0.14% to 2280. 3:59 PM In Q2, Apple (AAPL) beat by $0.09, and closed the next day +4% on positive analyst ...FDRY
Source: Google News

… simvastatin improves prognosis of diabetic patients with coronary heart disease. A subgroup analysis … -
K Pyorala, TR Pedersen, J Kjekshus, O Faergeman, … - Diabetes Care, 1997 - ncbi.nlm.nih.gov
... OBJECTIVE: To assess in diabetic patients with coronary heart disease (CHD) the
effect of ... 0.30-1.08; P = 0.087), major CHD events 0.45 (95% CI, 0.27-0.74; P ...

A Preliminary Study of Diltiazem in the Prevention of Coronary Artery Disease in Heart-Transplant … -
JS Schroeder, SZ Gao, EL Alderman, SA Hunt, I … - New England Journal of Medicine, 1993 - content.nejm.org
... little from the base-line value of 2.32 ?0.22 mm (2.32 ?0.27 mm at ... Diltiazem in the
Prevention of Coronary Artery Disease in Heart-Transplant Recipients ...

Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the … -
MJ Stampfer - International Journal of Epidemiology, 2004 - IEA
... heart disease: a quantitative assessment of the ... 3 of 9 Table 2 Community/population-
based case-control studies of estrogen use on heart disease risk Age of ...

Dietary intake of {alpha}-linolenic acid and risk of fatal ischemic heart disease among women -
FB Hu, MJ Stampfer, JAE Manson, EB Rimm, A Wolk, … - American Journal of Clinical Nutrition, 1999 - Am Soc Nutrition
... who rarely consumed this food (RR: 0.46; 95% CI: 0.27, 0.76; P ... Key Words: Ischemic
heart disease ? diet ? -linolenic acid ? risk ? Nurses' Health Study ...

Folate and Vitamin B6 From Diet and Supplements in Relation to Risk of Coronary Heart Disease Among … -
EB Rimm, WC Willett, FB Hu, L Sampson, GA Colditz, … - JAMA, 1998 - Am Med Assoc
... Relative Risk (RR) and 95% Confidence Interval (CIs) of Coronary Heart Disease
(CHD) (Nonfatal ... more than 1 drink per day, the comparable RR was 0.27 (95% CI ...

Coronary heart disease mortality and adjuvant tamoxifen therapy -
JP Costantino - J Natl Cancer I, 1997 - jnci.oxfordjournals.org
... The corresponding relative hazard of death from definite fatal heart disease (tamoxifen
versus placebo) was 0.66 (95% confidence interval = 0.27-1.61). ...

Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids … -
EB Rimm, P Williams, K Fosher, M Criqui, MJ … - BMJ, 1999 - pubmedcentral.nih.gov
... The coefficient for 11 studies with only beer (b=0.27) was slightly stronger ... greatly
and few such markers have been linked with risk of coronary heart disease. ...

Explained and Unexplained Ischemic Heart Disease Risk after Renal Transplantation -
BL KASISKE, HA CHAKKERA, J ROEL - Journal of the American Society of Nephrology, 2000 - Am Soc Nephrol
... Whether the high incidence of ischemic heart disease (IHD) among ... risk calculated
from the Framingham Heart Study (FHS ... even lower relative risk of 0.27 (0.11 to ...

… explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly … -
ICW Arts, PCH Hollman, EJM Feskens, HB Bueno de … - American Journal of Clinical Nutrition, 2001 - Am Soc Nutrition
... associated with ischemic heart disease mortality; the multivariate-adjusted risk
ratio in the highest tertile of intake was 0.49 (95% CI: 0.27, 0.88; P for ...

Frequent nut consumption and risk of coronary heart disease in women: prospective cohort study -
FB Hu, MJ Stampfer, JE Manson, EB Rimm, GA Colditz … - BMJ, 1998 - pubmedcentral.nih.gov
... week), the inverse association was particularly strong (relative risk of coronary
heart disease for consumption of nuts 5 times per week was 0.48 (0.27 to 0.84 ...

Source: Google Scholar
 

Ischaemic heart disease, characterised by reduced blood flow to the heart, is Australia's and the world's leading cause of death. It is most common in older people and the impact of the disease will continue to rise with an ageing population.

Director of Griffith's Heart Foundation Research Centre Professor John Headrick said older hearts become less resistant to damage during heart attack.

"Furthermore, new experimental therapies to reduce damage also appear less effective in older hearts. It is therefore critical that we understand how age alters the heart, and how older hearts respond to disease."

Together with researcher Dr Jason Peart, his team have identified normally protective processes within cardiac cells that become ineffective with age.

"When we experimentally target this 'cascade of proteins' it is possible to render an aged heart akin to a young heart in terms of its response to a heart attack. This type of research paves the way for new therapies designed to specifically manage heart disease in our older population," Professor Headrick said

Article continues below and (thank you)

 
The research is currently supported by grants from the National Heart Foundation and research fellowships from the National Health and Medical Research Council (NHMRC).

Dr Jason Peart completed his undergraduate degree at Griffith and PhD in the Heart Foundation Research Centre, before moving to the US for a prestigious postdoctoral position supported by the American Heart Association.

He was lured back to Australia with a NHMRC Howard Florey Centenary Research Fellowship - a scheme designed to counteract the brain drain of Australian talent - and has since been awarded an NHMRC Career Development Award.

The award, which supports early career researchers who have demonstrated excellence in their respective fields, allows Dr Peart to continue studying the particular roles of adenosine and opioids in triggering the protein cascades to produce heart cell protection.
 
http://www.researchaustralia.com.au/homePage.asp?id=1&parent_id=1
 
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