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Recent News and Articles on the Keywords: injury + brain + may  Related to the article below (Last Update: 8/5/2008)

Pentagon spends $300M to study troops' stress, trauma
USA Today -
Gregory O'Shanick, national medical director for the Brain Injury Association of America, says the funding initiative is "without a doubt ? an all-time ...
LegalView Brain Injury Site Reports Department of Veteran Affairs ...
PR-CANADA.net (press release), Montenegro -
Individuals who have been injured in a TBI accident may be advised to seek out experienced traumatic brain injury attorneys in order to receive the best ...
Cerebral Malaria May Be A Major Cause Of Brain Injury In African ...
Science Daily (press release) - Jul 29, 2008
John and Boivin are currently conducting a new study in Uganda to look at how the body's response to malaria infection may be leading to brain injury. ...
Obama, Bayh Urge Gates to Increase Medical Care for Iraq Vets
ABC News -
Citing Woodruff's recovery as evidence of "the vital role that cognitive rehabilitation plays in facilitating meaningful recovery from brain injury", ...

Voice of America
Ten Percent of Healthy People Injured from Silent Strokes
Voice of America -
This week, we will tell about a brain injury known as silent stroke. We will also tell about melanoma -- the most deadly form of skin cancer. ...
Health Front and Center
Publishers Weekly, NY -
In January 2008, Demos Health published its third edition of Brainlash: Maximize Your Recovery from Mild Brain Injury by Gail L. Denton, and this summer it ...
Sad toll in Placer's shaken baby death prosecutions
Sacramento Bee,  USA -
Placer District Attorney Brad Fenocchio said physicians who attended to Hannah at the hospital concluded that she suffered brain injuries caused by a ...
More Marshall Loeb's Daily Money Tip stories
MarketWatch -
He is looking for a car or truck, and the motorcycle may not register on his brain. 30% of cycle accidents occur this way. 4. When a car or truck is stopped ...
Senators Press Pentagon On Health Care
CBS News, NY -
... and eight other senators urged the Pentagon on Monday to expand health benefits to cover cognitive rehabilitation treatments for traumatic brain injury. ...
Golf: After near-death accident, ex-ISU golfer eyes PGA Tour
DesMoinesRegister.com, IA -
"Unbelievable," said Julie Fidler Dixon, executive director of On With Life, which specializes in brain injury rehabilitation and treated Swanson. ...
Source: Google News

… neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury … -
Y Cheng, M Deshmukh, AD'Costa, JA Demaro, JM … - Journal of Clinical Investigation, 1998 - pubmedcentral.nih.gov
... [PubMed]; Johnston MV. Neurotransmitter alterations in a model of perinatal
hypoxic-ischemic brain injury. Ann Neurol. 1983 May;13(5):511?518. [PubMed]; ...

The role of excitatory amino acids and NMDA receptors in traumatic brain injury -
AI Faden, P Demediuk, SS Panter, R Vink - Science, 1989 - sciencemag.org
... Thus, excitatory amino acids contribute to delayed tissue damage after brain trauma;
NMDA antagonists may be of benefit in treating acute head injury. ...

… -6 released in human cerebrospinal fluid following traumatic brain injury may trigger nerve growth … -
T Kossmann, V Hans, HG Imhof, O Trentz, MC … - Brain Research, 1996 - Elsevier
... mRNA in different brain regions suggests that cy- tokines may regulate the ... been
described in a variety of neuropathologies including brain injury; however, the ...

Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of … -
GJ Bouma, JP Muizelaar, SC Choi, PG Newlon, HF … - J Neurosurg, 1991 - ncbi.nlm.nih.gov
... These results support the above hypothesis, and suggest that early ischemia after
traumatic brain injury may be an important factor determining neurological ...

… activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain … -
CN Oliver, PE Starke-Reed, ER Stadtman, GJ Liu, JM … - Proceedings of the National Academy of Sciences of the …, 1990 - pubmedcentral.nih.gov
... Cao W, Carney JM, Duchon A, Floyd RA, Chevion M. Oxygen free radical involvement
in ischemia and reperfusion injury to brain. Neurosci Lett. 1988 May 26;88(2 ...

Treatment of Traumatic Brain Injury with Moderate Hypothermia -
DW Marion, LE Penrod, SF Kelsey, WD Obrist, PM … - New England Journal of Medicine, 1997 - content.nejm.org
... for 24 hours in patients with severe traumatic brain injury and coma scores of 5
to 7 on admission hastened neurologic recovery and may have improved the ...

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss … -
JM Carney, PE Starke-Reed, CN Oliver, RW Landum, … - Proc Natl Acad Sci US A, 1991 - pubmedcentral.nih.gov
... Cao W, Carney JM, Duchon A, Floyd RA, Chevion M. Oxygen free radical involvement
in ischemia and reperfusion injury to brain. Neurosci Lett. 1988 May 26;88(2 ...

Prevalence of MR evidence of diffuse axonal injury in patients with mild head injury and normal head … -
RL Mittl - American Journal of Neuroradiology, 1994 - Am Soc Neuroradiology
... GT Manley, A. Ebel, M. Meeker, and AA Maudsley Volumetric Proton Spectroscopic Imaging
of Mild Traumatic Brain Injury AJNR Am. J. Neuroradiol., May 1, 2004; 25 ...

Predictors of family functioning and change 3 years after traumatic brain injury in children -
JMB Rivara, KM Jaffe, NL Polissar, GC Fay, S Liao, … - Archives of Physical Medicine and Rehabilitation, 1996 - Elsevier
... morbidity in children, trau- matic brain injury (TBI) often ... of family depres- sion
after injury diminished over ... These findings may be relevant when comparing ...

The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain -
D Giulian, J Chen, JE Ingeman, JK George, M … - Journal of Neuroscience, 1989 - neuroscience.org
... secretion of cytokines. Moreover, certain classes of immunosuppressive drugs
may be useful in the treatment of acute brain injury. ...

Source: Google Scholar
 

Pregnancy hormone may help with brain injury

Last Updated: 2007-05-08 16:32:20 -0400 (Reuters Health)

By Will Boggs, MD

NEW YORK (Reuters Health) - In adult patients with traumatic brain injury, treatment with the pregnancy-supporting hormone progesterone may improve outcomes -- especially in cases of moderate injury -- according to a report in the Annals of Emergency Medicine.

"I'd like physicians to appreciate the excitement and hope of finally identifying an agent for the treatment of traumatic brain injury -- and possibly other neurological injuries such as stroke, spinal cord injury, and multiple sclerosis," Dr. David W. Wright told Reuters Health. "No current therapy exists that improves the outcome of brain injury patients."

Wright from the School of Medicine at Emory University, Atlanta, and colleagues conducted a trial to assess the safety and potential benefit of administering intravenous progesterone to 100 patients with brain injury. Patients were randomly assigned to receive progesterone or inactive "placebo."

Article continues below and (thank you)
 

Brain pressure remained stable in progesterone-treated patients, the authors report, whereas it tended to increase in the placebo group. Increases in brain pressure raise the risk of brain damage.

Progesterone patients remained in coma longer than placebo patients, the report indicates, but just 13 percent of progesterone-treated patients died within 30 days of injury compared with 30.4 percent of placebo patients.

The reduction in death risk seen with progesterone was most prominent among patients with more severe brain injury, the investigators state.

On the other hand, at 30 days, survivors of severe brain injury who had received placebo were slightly less disabled than those who had received progesterone, the report indicates. Patients with moderate traumatic brain injury who had received progesterone were significantly less disabled than those who had received placebo.

Side effects were comparable between the progesterone and placebo groups, the researchers note.

"We are trying to gather enough data to make sense of the 1 year outcomes," Wright said. "So far, we have only been able to assess about 40 percent of the enrolled subjects."

SOURCE: Annals of Emergency Medicine, April 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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