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Recent News and Articles on the Keywords: glioblastoma multiforme + glioblastoma multiforme: + glioblastoma  Related to the article below (Last Update: 8/5/2008)

Bradmer initiates enrollment for Phase III glioblastoma multiforme ... Trading Markets (press release), CA - Jul 24, 2008 ... III Glass-Art trial evaluating Neuradiab, a monoclonal antibody conjugated to Iodine-131, as a front-line therapy for primary glioblastoma multiforme. ...TSE:BMR - OTC:CMTX Bradmer Initiates Enrollment for Phase III Glioblastoma Multiforme ... RedOrbit, TX - Jul 24, 2008 ... III Glass-Art trial evaluating Neuradiab, a monoclonal antibody conjugated to Iodine-131, as a front-line therapy for primary glioblastoma multiforme. ...TSE:BMR AVANT to Report Second Quarter 2008 Financial Results on August 6 ... Centre Daily Times, PA - ... with its lead candidate, CDX-110, currently undergoing evaluation in a Phase 2/3 clinical trial in newly diagnosed glioblastoma multiforme, ...AVAN Drug combo may improve cancer therapy efficacy Newstrack India, India - Aug 2, 2008 Previous studies have shown that therapeutics targeting RTKs would likely be beneficial to individuals with glioblastoma multiforme (GBM), one of the most ... Bradmer reports progression free survival data from previous Phase ... CNW Telbec (Communiqu?s de presse), Canada - Jul 17, 2008 About Neuradiab Neuradiab is a monoclonal antibody, conjugated to radioactive iodine, used to treat glioblastoma multiforme (GBM), the most common and most ...TSE:BMR Nanomagnets tackle cancer Science News - The most advanced trial is currently studying some 65 patients with late-stage, recurrent glioblastoma multiforme, a type of brain cancer. ... Bradmer initiates enrollment in Phase III GLASS-ART Trial in ... Canada NewsWire (press release), Canada - Jul 23, 2008 About Neuradiab(TM) Neuradiab is a monoclonal antibody, conjugated to radioactive iodine, used to treat glioblastoma multiforme (GBM), the most common and ... Bradmer Initiates Enrollment in Phase III GLASS-ART Trial in ... PharmaLive.com (press release) all 7 news articles »  TSE:BMR Exelixis hopes for Glaxo licensing payment CNNMoney.com - Jul 28, 2008 The drug candidate is also being studied as a possible lung cancer treatment and for glioblastoma multiforme, the most common type of brain cancer. Exelixis Notifies GlaxoSmithKline of Proof-of-Concept for XL184 Business Wire (press release) Exelixis Notifies GlaxoSmithKline Of Proof-of-Concept For XL184 ... RTT News all 17 news articles »  EXEL - GSK Overcoming Inhibitors Of Cell Death Improves Cancer Therapy Efficacy Science Daily (press release) - Aug 2, 2008 1, 2008) ? Individuals with glioblastoma multiforme (GBM), one of the most aggressive types of brain tumor, have an extremely poor prognosis. ... Immune and Clinical Responses Seen with Glioblastoma Vaccination Cancerpage.com, GA - Jul 17, 2008 In the current phase II investigation, Dr. Wheeler's team assessed the immune responses and clinical outcomes of 32 patients with glioblastoma multiforme ...

Glioblastoma Multiforme

Glioblastoma multiforme is the highest grade glioma (grade 4) tumor and is the most malignant form of astrocytomas. These tumors originate in the brain.

General symptoms of this type of tumor are the same as for brain tumors. Specific symptoms will depend on the size and location of the glioblastoma multiforme.

Although glioblastoma multiforme brain tumors can occur at almost any age, they're most common after 50 years of age.

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A neurologic evaluation should be done if a patient has slowly increasing signs of mental dysfunction, new seizures, persistent headaches or evidence that there is pressure inside the skull, such as vomiting or swelling or protrusion of the blind spot at the back of the eye.

A neurologist (a doctor who has received special additional training in the diagnosis and treatment of disorders of the brain, spinal cord and nerves) performs a complete examination, which may include a magnetic resonance imaging (MRI) scan, a computed tomography (CT or CAT) scan or a chest X-ray to determine if the tumor has spread from another part of the body. An MRI usually finds low-grade astrocytomas earlier than CT. Cerebral angiography is rarely used to diagnose a brain tumor, but it may be done before surgery.

Depending on the patient's symptoms, specialized tests may be done, including tests of the field of vision, the sharpness of vision and hearing. If the results of other tests are not conclusive, an examination of the fluid that surrounds the brain and spinal cord may be done, although it is usually unnecessary.

Treatment of a brain tumor depends on the nature of the tumor, how rapidly it is growing, what symptoms it causing and where it is located. Radiation therapy is required to treat gliomas. Chemotherapy also benefits some patients with such tumors.

Research is being done on a number of techniques that in the future might help treat gliobastoma multiforme, including:

• Radioactive seed implants
• Stereotactic radiosurgery
• New forms of chemotherapy

Only about one out of every four patients with this type of tumor survives two years. Prospects are better when:

• The patient is younger than 45
• All or most of the tumor can be removed
• The tumor turns out to be an anaplastic astrocytoma, which is one stage less severe than gliobastoma multiforme