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Recent News and Articles on the Keywords: ovarian cancer + ovarian cancer: + cancer  Related to the article below (Last Update: 7/8/2008)

Significant Proportion Of Men Told Wife's Cancer Was Incurable ...
Science Daily (press release) -
The researchers speculated that because ovarian cancer is often diagnosed at an advanced stage, husbands may have known about the severity of their wives' ...
Cancer risk not higher for IVF mums
The Age, Australia -
Women who undergo fertility treatment are no more likely to develop breast or ovarian cancer than any other female, an international review shows. ...
New Ovarian Stimulation Technique Offers More Cancer Patients The ...
Science Daily (press release) - Jul 7, 2008
"This new protocol would enable patients with cancers such as breast cancer and Hodgkin lymphoma to have ovarian stimulation and oocyte collection. ...

BBC News
New technique may allow more cancer patients to preserve their ...
Cancer Research UK - News & Resources, UK -
"This new protocol would enable patients with cancers such as breast cancer and Hodgkin lymphoma to have ovarian stimulation and oocyte (egg) collection," ...
New baby hope for cancer women The Press Association
New fertility technique targets women with cancer Reuters UK
Cancer patients' fertility hope BBC News
Telegraph.co.uk - Daily Mail
all 23 news articles »
Simple Blood Tests for Monitoring Cancer Patients
PR-USA.net (press release), Bulgaria -
Dr. Vegh-Goyarts notes, "Three examples of such substances that are most often tested are CA-125 for ovarian cancer, CA 15-3 for advanced breast cancer and ...
Running in underwear to help in cancer fight
Inland Valley Daily Bulletin, CA -
The expected number of annual cases of colorectal cancer is more than 150000. It is anticipated that more than 22000 new cases of ovarian cancer will arise ...
Honolulu Club fundraiser for cancer
KHNL-TV/KHBC/KOGG, HI - Jul 7, 2008
She also is a survivor of ovarian cancer, so the money will go to an organization to fund research on ovarian cancer. "Spinning would be a way to give back ...
Reproductive Concerns and Cancer Treatment: What You Need to Know
Cancer Consultants, ID - Jul 7, 2008
The risk of infertility following treatment depends on many factors, some of which include age at diagnosis, baseline ovarian reserve, type of cancer, ...

Sydney Morning Herald
Expert warns older mums of cancer risk
Sydney Morning Herald, Australia - Jul 5, 2008
The Garvan Institute's head of ovarian cancer research, Philippa O'Brien, said delaying childbirth increased not only the risk of infertility but also the ...

Cancer Monthly
DCA - a Cancer Treatment?
Cancer Monthly, NC -
Future research will also look at the potential benefit of DCA on other types of cancers, including ovarian cancer, and try to determine why some cancer ...
Source: Google News

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 -
Y Miki, J Swensen, D Shattuck-Eidens, PA Futreal, … - Science, 1994 - sciencemag.org
... Advancement of Science articles. A strong candidate for the breast and ovarian
cancer susceptibility gene BRCA1. Y Miki, J Swensen ...

Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium. -
DF Easton, D Ford, DT Bishop - American Journal of Human Genetics, 1995 - pubmedcentral.nih.gov
... Copyright notice. Breast and ovarian cancer incidence in BRCA1-mutation carriers. ...
A breast-ovarian cancer susceptibility gene maps to chromosome 17q21. ...

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer -
DJ Slamon, W Godolphin, LA Jones, JA Holt, SG Wong … - Science, 1989 - sciencemag.org
... Advancement of Science articles. Studies of the HER-2/neu proto-oncogene
in human breast and ovarian cancer. DJ Slamon, W Godolphin ...

… Compared With Paclitaxel and Cisplatin in Patients with Stage III and Stage IV Ovarian Cancer. -
WP McGuire, WJ Hoskins, MF Brady, PR Kucera, EE … - Obstetrical & Gynecological Survey, 1996 - obgynsurvey.com
... Cyclophosphamide and Cisplatin Compared With Paclitaxel and Cisplatin in Patients
with Stage III and Stage IV Ovarian Cancer. ... Progress in ovarian cancer. ...

Use of proteomic patterns in serum to identify ovarian cancer -
EF Petricoin, AM Ardekani, BA Hitt, PJ Levine, VA … - The Lancet, 2002 - Elsevier
... reserved. Fast track ? Mechanisms of Disease. Use of proteomic patterns in serum
to identify ovarian cancer. ... Detection of ovarian cancer. Examples ...

AIB1, a Steroid Receptor Coactivator Amplified in Breast and Ovarian Cancer -
SL Anzick, J Kononen, RL Walker, DO Azorsa, MM … - Science, 1997 - sciencemag.org
... [DOI: 10.1126/science.277.5328.965] Reports. AIB1, a Steroid Receptor Coactivator
Amplified in Breast and Ovarian Cancer. Sarah L. Anzick ...

PIK3CA is implicated as an oncogene in ovarian cancer -
L Shayesteh, Y Lu, WL Kuo, R Baldocchi, T Godfrey, … - Nat Genet, 1999 - palgrave-journals.com
... PIK3CA is implicated as an oncogene in ovarian cancer. ... Our observations suggest PIK3CA
is an oncogene that has an important role in ovarian cancer. Top. ...

… linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer -
DF Easton, DT Bishop, D Ford, GP Crockford - American Journal of Human Genetics, 1993 - pubmedcentral.nih.gov
... Copyright notice. Genetic linkage analysis in familial breast and ovarian cancer:
results from 214 families. ... Six families prone to ovarian cancer. Cancer. ...

The genetic attributable risk of breast and ovarian cancer. -
EB Claus, JM Schildkraut, WD Thompson, NJ Risch - Cancer, 1996 - ncbi.nlm.nih.gov
Cancer. 1996 Jun 1;77(11):2318-24. The genetic attributable risk of breast and
ovarian cancer. Claus EB, Schildkraut JM, Thompson WD, Risch NJ. ...

Estimates of the gene frequency of BRCA1 and its contribution to breast and ovarian cancer incidence … -
D Ford, DF Easton, J Peto - American Journal of Human Genetics, 1995 - pubmedcentral.nih.gov
... Copyright notice. Estimates of the gene frequency of BRCA1 and its contribution
to breast and ovarian cancer incidence. ... Determinants of ovarian cancer risk. ...

Source: Google Scholar
 

Ovarian Cancer

In the female body, two ovaries (each about an inch-and-a-half long) are located on the left and right sides of the uterus in the pelvic region. Ovaries produce hormones and hold egg cells, which can develop into a fetus when fertilized.

Each year more than 22,000 women in the United States learn that they have ovarian cancer.

When cancer cells are found in the lining of the ovary, the condition is called epithelial ovarian cancer. When malignant cells or tumor are found in the egg-producing cells, the condition is called germ cell ovarian cancer. Genetic screening can help determine if a woman is a carrier of a mutated (changed) gene and, therefore, at greater risk of developing the disease.

Article continues below and (thank you)

 
Symptoms

Often no symptoms are evident in the early stages of the disease. When symptoms appear, they may include:

  • Gas, nausea, indigestion that does not go away
  • Frequent urination
  • Unexplained change in bowel habits
  • Abnormal postmenopausal bleeding
  • Weight gain or loss
  • Pain during intercourse
  • Abdominal swelling and/or pain, bloating or a feeling of fullness. Ovarian cancer may spread to the sac inside the abdomen that holds the intestines, uterus and ovaries - causing fluid to accumulate and the abdomen to swell.
  • Shortness of breath caused by the spread of the disease to the muscle under the lung. Fluid buildup in the area makes it difficult for the patient to breathe.
If symptoms continue for longer than four to six weeks, patients should insist on a thorough pelvic examination by their doctor.

Risk Factors

  • A family history of the disease, especially in a mother, daughter or sister
  • Family history of breast or colon cancer
  • Being a woman who has had breast or colon cancer
  • Being a women older than age 50
  • Never having had children
  • Having taken certain fertility drugs
Diagnosis

A comprehensive medical history is taken, and a physical exam (including a pelvic examination) is performed. For this, the doctor inserts one gloved finger in the rectum and one in the vagina at the same time. The vagina, rectum and lower abdomen are probed for masses and growths. Taking a mild laxative or enema before the pelvic exam can be helpful. Other tests include:

  • A Pap smear (a common test for cancer of the cervix) is often part of the pelvic exam, though it does not offer a reliable way to diagnose ovarian cancer. Every woman should undergo regular rectal and vaginal pelvic examinations.
  • Transvaginal sonography and tumor markers are alternative ways of diagnosing ovarian cancer.
  • Ultrasonography aims high frequency sound waves at the ovaries. The echo pattern produced creates a picture called a sonogram. Healthy tissues, fluid-filled cysts and tumors produce different echoes.
  • A computed tomography (CT or CAT) scan, a series of computerized X-rays, allows doctors to see cancer cells.
  • A lower GI series, or barium enema, is a series of X-rays of the colon and rectum. Pictures are taken after the patient is given an enema with a white chalky solution containing barium. The barium outlines the colon and the rectum on the X-ray, which helps the doctor see tumors or other abnormal areas.
  • An intravenous pyelogram (IVP) is an X-ray of the kidneys and uterus taken when dye is injected into the body.
  • Blood tests measure a substance in the blood called CA-125. Ovarian cancer cells can produce this tumor marker. CA-125 is not always present in women with ovarian cancer, though it may be present in women who have benign ovarian conditions. This blood test cannot be used alone to diagnose cancer.
A biopsy (removing and examining tissue) of the ovaries is the only way to definitively diagnose cancer. If cancer is suspected, the surgeon removes the entire ovary (oophorectomy) because infected cells could escape and spread when cutting through the outer layer of the ovary. The surgeon also removes nearby lymph nodes, samples of tissue from the diaphragm and other organs and fluid from the abdomen. A pathologist examines these cells to identify cancer. This process, called surgical staging, is needed to find out whether the cancer has spread and to determine a plan for treatment.

Treatment

Treating ovarian cancer depends on a number of factors, including the stage of the disease and the woman's age and general health. Oncologists who specialize in this disease can best determine the treatment plan. Because treatment decisions are complex, more than one doctor's advice can be helpful.

When talking about choices, the patient may want to ask about taking part in a research study or clinical trial. These scientific studies are designed to find new and better ways to treat cancer. Ovarian cancer treatment possibilities are:

  • Surgery to remove the uterus, both ovaries and the fallopian tubes
  • Chemotherapy (anti-cancer drugs)
  • Radiation therapy (also called radiotherapy)
 
 
 
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