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Recent News and Articles on the Keywords: spina bifida + spina bifida: + spina  Related to the article below (Last Update: 8/5/2008)

Hard work, grit drive student By Joel Jacobson GREAT KIDS
TheChronicleHerald.ca, Canada - Aug 3, 2008
The 18-year-old from Linwood, Antigonish County, has spina bifida, a birth defect in which the bones of the spine do not form properly around the spinal ...
Pro-Life News: In-Vitro, Sex-Selection Abortions, Britain, South ...
LifeNews.com, MT -
The suit is in the name of Emil, who is expected to be born next week with spina bifida or split spine, a developmental defect that leads to an open spinal ...VTO
Bayh and Lugar seek health coverage for children of Agent Orange vets
Chesterton Tribune,  United States - Jul 31, 2008
Children of Vietnam and Korean War veterans faced an increased risk of being born with spina bifida, which can lead to severe physical and mental ...
Spina Bifida Association fundraiser is Saturday
Montgomery Advertiser, AL - Jul 23, 2008
The Spina Bifida Association of Alabama will host a bowl-a-thon from 11 am-1 pm July 26 at Brunswick Woodmere Lanes. The organization is asking bowlers to ...
Mom's abdominal fat linked with birth defect risk
Reuters UK, UK - Jul 25, 2008
The most common neural tube defects are spina bifida, in which the spinal cord fails to close completely during fetal development, and anencephaly, ...
Unborn child sues Austrian state over dignity of life
Monsters and Critics.com - Aug 1, 2008
The suit is in the name of Emil, who is expected to be born next week with spina bifida or split spine, a developmental defect that leads to an open spinal ...
Mystery Jets cancel festival shows
NME.com, UK - Jul 31, 2008
COM, the singer is receiving hospital treatment for ailments on his feet, a recurring injury relating to his Spina Bifida. Harrison though, is currently on ...
Mystery Jets and Cage the Elephant cancel Dales festival slots Matlock Today
Mystery Jets pull several festival shows Virtual Festivals
all 4 news articles »
U of L birth defect research center wins $10.3 million in grants
Louisville Courier-Journal, KY - Aug 1, 2008
Research will focus on finding the causes of infertility and birth defects, such as spina bifida, smoking-related defects and cleft palates. ...
U of L gets $10.3 million grant for Birth Defects Center Bizjournals.com
About the research Louisville Courier-Journal
all 8 news articles »

Soonews.ca
Biking for Spina Bifida & Hydrocephalus
Soonews.ca, Canada - Jul 9, 2008
The on-again-off-again marathon effort is to raise money and awareness of spina bifida and hydrocephalus, which has affected both a friend and a cousin of ...
Girl (10) with Spina Bifida hit by savage cutbacks
Donegal News (subscription), UK - Jul 11, 2008
BY CJ MCGINLEY A 10-year-old Letterkenny girl who has Spina Bifida may not be able to return to school in September because her personal assistant hours ...
Source: Google News

Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida. -
NM van der Put, RP Steegers-Theunissen, P Frosst, … - Lancet, 1995 - ncbi.nlm.nih.gov
... Mutated methylenetetrahydrofolate reductase as a risk factor for spina bifida.
van der Put NM, Steegers-Theunissen RP, Frosst P, Trijbels ...

The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort -
JG Omtzigt - Neurology, 1992 - AAN Enterprises
... of Neurology. ARTICLES. The risk of spina bifida aperta after first-trimester
exposure to valproate in a prenatal cohort. JG Omtzigt ...

… Synthase Reductase Combined with Low Cobalamin (Vitamin B12) Increases Risk for Spina Bifida -
A Wilson, R Platt, Q Wu, D Leclerc, B Christensen, … - Molecular Genetics and Metabolism, 1999 - Elsevier
... 12 ) Increases Risk for Spina Bifida ... 1999 Academic Press Key Words: spina
bifida; methionine synthase re- ductase; polymorphism. ...

A cluster of anaphylactic reactions in children with spina bifida during general anesthesia: … -
KJ Kelly, ML Pearson, VP Kurup, PL Havens, RS Byrd … - J Allergy Clin Immunol, 1994 - ncbi.nlm.nih.gov
... A cluster of anaphylactic reactions in children with spina bifida during general
anesthesia: epidemiologic features, risk factors, and latex hypersensitivity. ...

… Use, Genetic Variation of Infant Methylenetetrahydrofolate Reducatase, and Risk for spina Bifida -
GM Shaw, R Rozen, RH Finnell, CR Wasserman, EJ … - American Journal of Epidemiology, 1998 - Oxford Univ Press
... Press. ARTICLES. Maternal vitamin use, genetic variation of infant
methylenetetrahydrofolate reductase, and risk for spina bifida. GM ...

Spina bifida in infants of women treated with carbamazepine during pregnancy -
FW Rosa - New England Journal of Medicine, 1991 - content.nejm.org
... Next Next. Spina bifida in infants of women treated with carbamazepine during pregnancy.
FW Rosa. ... CARBAMAZEPINE DURING PREGNANCY INCREASES RISK OF SPINA BIFIDA. ...

Spina bifida outcome: a 25-year prospective. -
RM Bowman, DG McLone, JA Grant, T Tomita, JA Ito - Pediatr Neurosurg, 2001 - ncbi.nlm.nih.gov
... Forty-nine percent have scoliosis, with 43% eventually requiring a spinal fusion. ...
today is establishing a network of care for these adults with spina bifida. ...

Prevalence of Spina Bifida and Anencephaly During the Transition to Mandatory Folic Acid … -
LJ Williams, CT Mai, LD Edmonds, GM Shaw, RS Kirby … - Obstetrical & Gynecological Survey, 2003 - obgynsurvey.com
... Prevalence of Spina Bifida and Anencephaly During the Transition to Mandatory
Folic Acid Fortification in the United States. [OBSTETRICS ...

In utero surgery rescues neurological function at birth in sheep with spina bifida -
M Meuli, C Meuli-Simmen, GM Hutchins, CD Yingling, … - Nature Medicine, 1995 - nature.com
... J. Pathol. 110, 83-96 (1973). | PubMed | ISI | ChemPort |; Cameron, AH The spinal
cord lesion in spina bifida cystica. Lancet 2, 171-174 (1956). ...

Surveillance for anencephaly and spina bifida and the impact of prenatal diagnosis--United States, …
JD Cragan, HE Roberts, LD Edmonds, MJ Khoury, RS … - MMWR CDC Surveill Summ, 1995 - ncbi.nlm.nih.gov
1995 Aug 25;44(4):1-13. Click here to read Surveillance for anencephaly and spina
bifida and the impact of prenatal diagnosis--United States, 1985-1994. ...

Source: Google Scholar
 

Spina Bifida

Spina bifida refers to a range of spine deformities in which the bones of the spine do not fuse as a fetus develops. It is the most common abnormality of the spine seen at birth. Spina bifida may also involve the brain, nerves and coverings of the nerves (meninges). The two types are:

  • Occulta, in which abnormalities of the bones can be seen by X-ray. Skin changes or hairy patches can indicate that nerves may be involved.
  • Open, which is usually seen at birth. It involves abnormalities of the bones, nerves, spinal fluid or meninges.

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Symptoms

The spinal abnormalities are most commonly seen in the lower half of the spine. The baby may have an enlarged head from hydroencephalus, which sometimes develops as a consequence of spina bifida. When the spinal cord or the nerve roots in the lower back are involved, varying degrees of paralysis may be present below the involved level, usually affecting bladder and bowel functions. Since spina bifida occurs in the fetus, many problems can be seen at birth, such as a clubfoot or dislocated hip. There may be other birth defects as well.

Causes and Risk Factors

The cause of spina bifida is not well understood. Genetics may have a large role, but nutritional and environmental factors could play a part. Getting enough folic acid during pregnancy may prevent spina bifida.

Diagnosis

The open form is usually discovered at birth or during prenatal ultrasound screening. A mass may be apparent outside the body at the base of the spine. (A mass that contains nerves is called myelomeningocele, and one that does not is called meningocele.) Usually the deformity is covered with a thin membrane (spina bifida cystica), but it can also be open to the environment (spina bifida aperta). Spinal fluid may be seen draining from it. Tests and procedures that may be used to diagnose spina bifida include:

  • Blood tests
  • Evaluation of the fluid that surrounds the brain and spinal cord
  • Ultrasound
  • Urinary tract evaluation, including a urinalysis
  • X-rays of the spine, skull, hips and legs if they are badly formed

Treatment

The infant's health, the presence of any other abnormalities and the type, level and extent of the deformity all need to be assessed before treatment begins. There is no specific treatment for occult spina bifida if it is limited to the bone. If there are deformities of the spine, intervention may be necessary to prevent degenerative changes later in life. If spinal fluid is leaking from the defect, antibiotics and surgery are urgently needed to prevent spinal and brain infections. A shunt may be needed if hydroencephalus is present.

Open spina bifida and the spinal abnormalities that come with occult spina bifida are treated by a neurosurgeon. The goal of surgery is to preserve the nerves, restore the normal anatomy and close the defect. This delicate surgery is carefully performed under magnification using special monitors to help identify the nerves. Surgery helps reduce the risk of infection (meningitis) and the development of long-term disability.

Kidney function must be followed closely. Obstructions or infections of the kidney or bladder must be treated aggressively. If a clubfoot is present, it should be put in a cast to correct the deformity. Hip joints should be checked carefully. The infant should be monitored for the development of scoliosis, abnormal fractures, muscle weakness or spasm or pressure sores as he or she grows up to prevent further deformities.

 
 
 
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