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Recent News and Articles on the Keywords: salivary gland + salivary glands + gland  Related to the article below (Last Update: 8/5/2008)


Chicago Tribune
Rush: Rumors Of Demise Are Premature
NBC5.com, IL -
Rush, D-Chicago, who has been battling a rare salivary gland cancer for the past five months, was greeted with hugs from University of Chicago nurses and ...
Bobby Rush says he is cancer-free ABC7Chicago.com
Healthy Bobby Rush to Obama: Make health care a bigger focus Chicago Sun-Times
Congressman Rush: "I No Longer Have Cancer" CBS2 Chicago
all 9 news articles »
The buccal minor salivary glands as starting point for a ...
7thSpace Interactive (press release), NY - Jul 30, 2008
With the 2005 WHO classification of salivary gland tumours and its increasingly recognized diagnostic entities, the frequency of adenocarcinoma (NOS) has ...
Reader Views
The Tennessean, TN - Aug 4, 2008
However, research suggests a link between cell-phone use and glioma; cancer of the parotid, a salivary gland near the ear; and acoustic neuroma, ...
Rep. Rush returns to work in Congress after beating cancer
St. Louis Post-Dispatch,  United States - Aug 3, 2008
Bobby Rush returned Wednesday to the Capitol, five months after surgery for a cancerous tumor in his salivary gland and months of chemotherapy treatment. ...
Blogs help cancer patients cope with disease
Seattle Post Intelligencer - Jul 24, 2008
Hartman, a university librarian who traveled to Seattle from Omaha, Neb., was diagnosed with a rare cancer in the salivary glands in her cheek in July 2006. ...
Cancer Cell
American Chronicle, CA - Aug 3, 2008
She and her colleagues found that heavy cell phone users were subject to a higher risk of benign and malignant tumors of the salivary gland. ...
Bobby Rush returns to work after
ABC7Chicago.com,  USA - Jul 31, 2008
... colleagues who had called and wished him well during his battle with cancer. He says he is cancer free after surgery for a tumor on his salivary gland.
Sialo gets FDA nod for endoscope component
Globes, Israel - Jul 22, 2008
The FDA approved seven polymeric drains for the company's endoscope for salivary gland stones surgery. Sialo Technology Israel Ltd. (TASE: SALO) has ...
Sialo wins EU patent
Globes, Israel - Jul 8, 2008
The patent protects the polymers of the company's device for endoscopic and surgical treatment of salivary gland stones. Sialo Technology Israel Ltd. (TASE: ...

1010 Wins
Officials: LI Beach Club Employees Have Mumps
1010 Wins, NY - Jul 26, 2008
Mumps is an acute viral disease characterized by fever, swelling and tenderness of one or more of the salivary glands, including the parotid gland located ...
Source: Google News

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. -
MJ Berridge, CP Downes, MR Hanley - Biochemical Journal, 1982 - pubmedcentral.nih.gov
... Abstract. 1. The effect of Li+ on the agonist-dependent metabolism of [3H]inositol
has been studied in rat brain, rat parotid and the insect salivary gland. ...

… of Salivary Function and Excretion Response in Radiation-Induced Injury of the Major Salivary Glands -
S Glands - doi.wiley.com
... Page 2. Radiation-Induced Major Salivary Gland Injury/Valdb Olmos et al. 2887 ... 2);
in 3 Page 4. Radiation-Induced Major Salivary Gland lnjury/Vald& Olmos et al. ...

Labial salivary gland biopsy in Sjogren's disease -
DM Chisholm, DK Mason - British Medical Journal, 1968 - jcp.bmj.com
... DM Chisholm and DK Mason Sj?gren's disease Labial salivary gland biopsy in ... Labial
salivary gland biopsy in Sjogren's disease DM CHISHOLM AND D. K. MASON ...

Primary B-cell lymphoma of salivary glands and its relationship to myoepithelial sialadenitis. -
E Hyjek, WJ Smith, PG Isaacson - Hum Pathol, 1988 - ncbi.nlm.nih.gov
... on salivary glands excised from 20 cases in which the initial histologic diagnosis
was either myoepithelial sialadenitis (MESA) or salivary gland lymphoma (SGL ...

Cytokine mRNA expression in salivary gland biopsies of Sjogren's syndrome -
RI Fox - The Journal of Immunology, 1994 - Am Assoc Immnol
... American Association of Immunologists. ARTICLES. Cytokine mRNA expression in
salivary gland biopsies of Sjogren's syndrome. RI Fox, HI Kang ...

Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site … -
JW Eveson, RA Cawson - J Pathol, 1985 - ncbi.nlm.nih.gov
J Pathol. 1985 May;146(1):51-8. Salivary gland tumours. ... To date the British Salivary
Gland Tumour Panel has accumulated 2569 salivary gland tumours. ...

Protein synthesis in salivary glands of Drosophila melanogaster: Relation to chromosome puffs. -
A Tissieres, HK Mitchell, UM Tracy - J Mol Biol, 1974 - ncbi.nlm.nih.gov
1974 Apr 15;85(3):389-98. Protein synthesis in salivary glands of Drosophila
melanogaster: Relation to chromosome puffs. Tissieres A, Mitchell HK, Tracy UM. ...

Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity -
RG Titus, JM Ribeiro - Science, 1988 - sciencemag.org
... Science articles. Salivary gland lysates from the sand fly Lutzomyia longipalpis
enhance Leishmania infectivity. RG Titus and JM Ribeiro ...

Purification of a Nerve-Growth Promoting Protein from the Mouse Salivary Gland and its Neuro- … -
S Cohen - Proceedings of the National Academy of Sciences of the …, 1960 - JSTOR
Purification of a Nerve-Growth Promoting Protein from the Mouse Salivary Gland
and its Neuro-Cytotoxic Antiserum. Stanley Cohen. Proceedings ...

Tumors of the intraoral minor salivary glands: a demographic and histologic study of 426 cases.
CA Waldron, SK el-Mofty, DR Gnepp - Oral Surg Oral Med Oral Pathol, 1988 - ncbi.nlm.nih.gov
... In a demographic and histologic study of 426 oral minor salivary gland tumors, 57.5%
were classified as benign and 42.5% were classified as malignant or ...

Source: Google Scholar
 

Salivary Gland Diseases and Tumors

The salivary glands produce saliva to moisten the mouth, to help protect teeth from decay and to digest food. The three major salivary glands are the parotid gland, submandibular gland (also called the submaxillary gland), and sublingual glands. Saliva drains into the mouth through small tubes called ducts

  • The parotid gland makes 25% of the saliva and drains into the mouth near the upper teeth.
  • The submandibular gland makes 70% of the salvia and drains into the mouth from under the tongue.
  • The sublingual gland makes 5% of the saliva and drains into the floor of the mouth.

In addition, 600-1000 tiny glands (the minor salivary glands) are located in the lips, inner cheek, and in the lining of the mouth and throat.

The most common cause of problems in the salivary gland occurs when the ducts become blocked and saliva cannot drain.

Article continues below and (thank you)

 

Problems with the ducts

Sialolithiasis (sigh a lo THIGH a sis) is a condition where tiny salivary stones form in the glands. The stones, called sialoliths, are made of calcium.

Some stones do not cause any symptoms, but some stones block the ducts. The saliva flow is partially or completely stopped. The gland might enlarge and an infection can develop.

Sialadenitis (sigh a la dent I tis) is a painful infection of a salivary gland. Staphylococcus, streptococcus, Haemophilus influenzae or anaerobic bacteria are usually the cause. The condition is common with elderly adults who have salivary gland stones, but infants can also develop sialadenitis during the first few weeks of life.

Sialadenitis can become a severe infection if not treated properly.

Viral infections such as mumps, flu, Coxsackie viruses, echovirus and cytomegalovirus can cause the salivary glands enlarge.

Cysts can develop in the salivary glands after injuries, infections, stones or tumors. Sometimes babies are born with cysts in the paratoid gland because of a problem with early development of the ears.


Tumors

Most salivary tumors are benign (non- cancerous), but they can also be cancerous. The parotid is the most common gland for salivary tumors to grow.

Pleomorphic adenomas are the most common parotid tumor. It grows slowly and is benign. A pleomorphic adenoma begins as a painless lump at the back of the jaw, just below the earlobe. These are more common in women.

Benign pleomorphic adenomas can also grow in the submandibular gland and minor salivary glands, but less often than in the parotid.

Warthin's tumor is the second most common benign tumor of the parotid gland. It is more common in older men and can grow on both sides of the face.

Cancerous (malignant) tumors are rare in the salivary glands and usually occur between ages 50 to 60. Some types grow fast and some are slow-growing.


Other salivary gland conditions

Sjögren's (SHOW grins) syndrome is chronic disease. White blood cells attack the moisture-producing glands such as the salivary glands, the tear-producing glands, and sometimes the sweat and oil glands. Middle-aged women are most affected. Sjögren's syndrome is frequently seen in people who have rheumatoid arthritis, lupus, scleroderma and polymyositis.

Sialadenosis is a painless enlargement of the salivary gland without a known cause. The paratoid is usually the affected gland.


Symptoms

Sialolithiasis usually begins as a painful lump under the tongue. The stone blocks the flow of saliva so pain might increase while eating.

Sialadenitis creates a painful lump in the cheek or under the chin. Foul-tasting pus drains into the mouth. Fever can occur.

Generalized viral infections cause fever, headache, muscle aches and joint pain in the entire body. If the virus settles in the parotid glands, both sides of the face enlarge in front of the ears.

A mucocele, a common cyst on the inside of the lower lip, can burst and drain yellow mucous. Other cysts can hinder eating, speaking or swallowing.

With tumors, a cancerous or non-cancerous lump can grow in the roof of the mouth, the cheek, on the tongue or under the chin. It often glows slowly and is painful.

Sjögren's syndrome causes decreased moisture in glands. Dry mouth, tooth decay, mouth sores, enlarged salivary glands, sialoliths, and recurrent salivary gland infections are possible symptoms. The syndrome also effects moisture in the eyes, which might cause chronic eye infections, corneal ulcers and vision loss.

Sialadenosis is usually painless, but the paratoid glands enlarge.


Diagnosis

Your doctor will ask questions about your symptoms and medical history. During the physical, the doctor will examine your head, neck and the inside of your mouth for lumps or areas of pain.

The doctor might order:
  • An X-ray, CT scan or MRI to look for stones or tumors
  • A fine needle biopsy (FNA) is needed to determine if a tumor is cancerous.
  • Salivary function tests, eye tests and blood tests to diagnosis Sjögren's syndrome
  • A sialogram X-ray that uses dye to look for problems in the salivary ducts


Causes and Risk Factors

The exact cause of stone formation is not known, but certain factors might contribute to the condition:

  • Dehydration, which thickens the saliva
  • Decreased food intake that lowers the demand for saliva
  • Antihistamines, blood pressure medications, psychiatric medications and other medication can decrease saliva production

Factors that increase the risk to develop sialadenitis are:

  • Dehydration, malnutrition, eating disorders
  • Recent surgery, chronic illness, cancer, prematurity
  • Antihistamines, diuretics, psychiatric medications, blood pressure medications, barbiturates
  • History of Sjögren's syndrome
  • Air blowing occupations (trumpet playing, glass blowing)
Risk factors for pleomorphic adenomas include:
  • Radiation exposure
  • Smoking

The risk factors for salivary gland cancers are:

  • Sjögren's syndrome
  • Exposure to radiation
  • Smoking

Sialadenosis is more likely to develop in people who are obese, pregnant or breastfeeding, are malnourished or have eating disorders, alcoholics with liver cirrhosis, and those who have kidney failure or thyroid problems.


Treatments

Small stones might pass out of the duct without treatment. A doctor might be able to remove a stone by pressing on it if the stone is close to the opening of a duct.

Ultrasoundic waves can be used to shatter large stones into small pieces.

Deep or large stones are more difficult. If they cannot be removed, and symptoms of pain or infection persist, the entire salivary gland may need to be removed.

Bacterial infections require taking antibiotics and extra fluid either by mouth or intravenously (IV). Warm compresses are placed on the infected gland. Chewing sour candies encourages the flow of saliva.
Surgery may be needed to drain the gland.

Antibiotics do not help cure a viral infection. The body must use it own defense system to clear itself of a virus. Bed rest, increased fluids, and acetaminophen for fever are the best ways to help the body cure itself.

Small cysts may drain without treatment. Large cysts might need surgery.

Benign tumors usually require surgery to remove them. Some are treated with radiation to prevent recurrence.

Malignant tumors require surgery if possible. Some tumors need surgery only; others require radiation and chemotherapy in addition to surgery. Radiation and chemotherapy are also used for tumors that are inoperable.

Prescribed medications help decrease dry mouth.

 
 
 
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