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Recent News and Articles on the Keywords: boost + clinical + online  Related to the article below (Last Update: 8/5/2008)

Cold-fX safe for kids: maker
Calgary Herald,  Canada -
CV Technologies now expects to launch large-scale clinical trials of Cold-fX's effectiveness in treating symptoms in children, Shan said. ...
Schools gain research dollars
Indianapolis Star, United States -
By Laura Olson Indiana's two largest universities saw increases in their research funding last year and attribute the boost to internal partnering and ...
Ginseng, flaxseed look promising in initial trial results
Rocky Mountain News, CO -
Two studies presented at the 2007 meeting of the American Society of Clinical Oncology suggest that flaxseed and ginseng can help patients. ...
Nuance?s healthcare division announces significant traction in New ...
HealthTech Wire (press release), Germany - 22 minutes ago
Today, Nuance solutions are used by nearly 300 healthcare organizations in this region to drive speech-enabled clinical documentation and improved ...NUAN
Abbott faces suits on AIDS drug
Santa Rosa Press Democrat, CA -
The lawsuits, all filed in Oakland federal court, accuse Abbott of raising the price of the HIV-fighting Norvir to illegally stifle competition and boost ...ABT
Abbott faces more litigation over AIDS drug
The Associated Press - Aug 3, 2008
The lawsuits, all filed in Oakland federal court, accuse Abbott of raising the price of the HIV-fighting Norvir to illegally stifle competition and boost ...ABT
East Lancashire heath chief vows to boost staff morale
Lancashire Telegraph, UK - Aug 1, 2008
She has already begun the process of changing management structures ? from September, all policy decisions will have to be approved jointly by clinical, ...
Online Courses Boost Infection Control Skills That Could Prove ...
Science Daily (press release) - Jul 10, 2008
Asking for better-equipped isolation carts to be provided, together with hand sanitisers in non-clinical areas of the hospital. Re-examining waste disposal ...
YAKIMA HERALD-REPUBLIC
RedOrbit, TX -
Kathleen Ross, president of Heritage University in Toppenish, looks to the new school as a boost to undergraduates as well. "Heritage's programs in clinical ...

BBC News
New guidelines to boost stroke care
The Press Association - Jul 22, 2008
The two new guidelines were published by the National Institute for Health and Clinical Excellence (Nice) and the Royal College of Physicians. ...
Poor stroke care 'still common' BBC News
all 122 news articles »
Source: Google News

… bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical … -
KC Wollert, GP Meyer, J Lotz, S Ringes Lichtenberg … - The Lancet, 2004 - Elsevier
... and IST, Mannheim, Germany Available online 9 July ... Early clinical investigations
indicate that infusion of ... elevation infarct regeneration (the BOOST trial) was ...

Pre-clinical development of a multi-CTL epitope-based DNA prime MVA boost vaccine for AIDS -
T Hanke, A McMichael - Immunology Letters, 1999 - Elsevier
... Available online 8 March 1999 ... injection of DNA in the DNA prime-MVA boost immunization
protocol ... Therefore, it was important to test prior to clinical trials the ...

Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in … -
SH van der Burg, KMC Kwappenberg, TO'Neill, RMP … - Vaccine, 2001 - Elsevier
... Available online 22 June 2001. ... CTL, T-helper cells and antibodies in a pre-clinical
mouse model ... when TA-CIN was employed in heterologous prime-boost regimens in ...

… -modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II?clinical … -
A Lauve, M Morris, R Schmidt-Ullrich, Q Wu, R … - International Journal of Radiation Oncology, Biology, …, 2004 - Elsevier
... Available online 16 September 2004 ... by objective measures, the clinical judgment that ...
than established accelerated hyperfractionated concomitant boost regimens [1 ...

Conformal radiotherapy, reduced boost volume, hyperfractionated radiotherapy, and online quality … -
C Carrie, X Muracciole, F Gomez, JL Habrand, M … - International Journal of Radiation Oncology, Biology, …, 2005 - Elsevier
... of at least 6 h. The boost volume encompassed ... The prescribed dose to this clinical
target volume was 32 ... control processes was that we use online quality control ...

… I Study in Advanced Cancer Patients of a Diversified Prime-and-Boost Vaccination Protocol Using … -
JL Marshall, RJ Hoyer, MA Toomey, K Faraguna, P … - Journal of Clinical Oncology, 2000 - jcojournal.org
... Patients who received avipox-CEA in a previous clinical trial were able to ... were not
included in the evaluations to define the optimal prime-and-boost protocol. ...

Phase I clinical trial safety of DNA-and modified virus Ankara-vectored human immunodeficiency virus … -
I Cebere, L Dorrell, H McShane, A Simmons, S … - Vaccine, 2006 - Elsevier
... In the prime-boost study IAVI-005, 9 volunteers ... considered to be of no clinical
significance by ... in Oxford enrolled volunteers using an online internet-based ...

A clinical trial of prime-boost immunisation with the candidate malaria vaccines RTS, S/AS02A and … -
SJ Dunachie, M Walther, JM Vuola, DP Webster, SM … - Vaccine, 2006 - Elsevier
... c and Adrian VS Hill a a Centre for Clinical Vaccinology and ... Available online 6 January
2006. ... Heterologous prime-boost immunisation with RTS,S/AS02A and the ...

… : Eighteen Months' Follow-Up Data From the Randomized, Controlled BOOST (BOne marrOw transfer to … -
GP Meyer, KC Wollert, J Lotz, J Steffens, P … - Circulation, 2006 - Am Heart Assoc
... In via User Name/Password Published online before print ... cell transfer after myocardial
infarction: the BOOST randomised controlled clinical trial. ...

… poxviruses expressing PSA in hormone dependent prostate cancer: Follow-up clinical results from ECOG … -
HL Kaufman, W Wang, J Manola, RS Dipaola, YJ Ko, … - Journal of Clinical Oncology, 2005 - asco.org
... Prime/boost vaccination using poxviruses expressing PSA in ... Journal of Clinical Oncology
Articles by HL Kaufman. ... This online resource is supported by: Edit item. ...

Source: Google Scholar
 

 

WHO moves to boost online data of clinical trials

Last Updated: 2007-05-04 13:26:12 -0400 (Reuters Health)

By Stephanie Nebehay

GENEVA - The World Health Organisation (WHO) said on Friday it was improving access online to data on clinical trials in the wake of high-profile cases of drugs being tested with possibly harmful side-effects.

A new Web site aims to help researchers, doctors and patients obtain reliable information on high-quality clinical trials, it said in a statement.

 

Article continues below and (thank you)
 

 

Currently a "significant proportion" of trial research is never published, meaning doctors can lack information about treatment options, according to the United Nations agency.

Another problem is the selective reporting of clinical trial findings, which can end up being misleading, WHO officials say.

"WHO believes that the registration of clinical trials is a scientific, ethical and moral responsibility."

Initially, data from 50,000 clinical trials provided by three registers -- in Britain, Australia/New Zealand and the United States -- have been put on the WHO site, which is www.who.int/trialsearch .

Registers submitting data must ensure they meet a minimum quality standard and that all trials are registered before any participants are recruited. Data will not be accepted directly from drug companies.

"The Clinical Trial Search Portal is a collaborative international initiative led by WHO that facilitates the identification of all clinical trials, regardless of whether or not they have been published," said Tim Evans, assistant WHO director-general for information evidence and research.

Since Merck & Co Inc's 2004 recall of painkiller Vioxx, after a clinical trial found it increased the rate of heart attacks among long-term users, concerns have grown about side effects of some prescription medicines.

In 2004, the U.S. Food and Drug Administration advisory panel began requiring a black box warning on prescriptions for selective serotonin reuptake inhibitors (SSRI), a type of antidepressant, based on reports that fluoxetine (Prozac) increased suicidal thoughts in children and adolescents.

Such cases have led to growing pressure for greater transparency.

"You can go to one place (online) and search all registers at once and identify clinical trial research underway around the world," Davina Ghersi of WHO's department of research policy and cooperation said.

The network of registers, which are required to disclose their ownership, governance structure and for-profit status, will be expanded to make it more comprehensive.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
 
 
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