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Recent News and Articles on the Keywords: alcohol + hemorrhaging + consumption  Related to the article below (Last Update: 8/4/2008)

Visualize the Dow at 6000
Online Journal, FL - Jul 24, 2008
Personal consumption is down, the labor market is softening, and food and fuel prices are soaring. Housing values are plummeting, wages have stagnated, ...
Source: Google News

Factors Related to Reductions in Alcohol Consumption among College Students: The Role of Religious … -
ML BORYNSKI - Current Psychology, 2003 - Springer
... motivations were also significant in predicting alcohol consumption. ... lead to strokes,
brain hemorrhaging, and sudden ... students reported using alcohol and other ...

[CITATION] Social Security Benefits for Disability Related to Alcohol Consumption
JH King Jr - Tenn. L. Rev., 1982 - HeinOnline

… attenuates alcohol-induced cerebral vascular damage in rats: possible role of oxidants in alcohol … -
BM Altura, A Gebrewold - Neuroscience Letters, 1996 - Elsevier
... Table 1 a-Tocopherol chronic administration attenuates spasm, rupture and hemorrhaging
in intact ... [12] Camargo, CA Jr., Moderate alcohol consumption and stroke ...

Comparative effects of prenatal cocaine, alcohol, and undernutrition on maternal/fetal toxicity and … -
MW Church, CA Morbach, MG Subramanian - Neurotoxicology and Teratology, 1995 - Elsevier
... exposed and alcohol-exposed fetuses included occasional hemorrhaging, edema,
anophthalmia, and limb reduction. Despite increased maternal water consumption by ...

Long-term Follow-up of Jejunoileal Bypass Patients with Preoperative Cirrhosis of the Liver -
CE Wills - Obesity Surgery, 1994 - Springer
... GB died four days after surgery due to hemorrhaging esophageal varices. LD, who
continued excessive alcohol consumption, died of hepatic failure 5 months ...

Magnesium Deficiency Exacerbates Brain Injury and Stroke Mortality Induced by Alcohol: A 31P-NMR In … -
BM Altura, A Gebrewold, A Zhang, BT Altura, RK … - Alcohol, 1998 - Elsevier
... of ethanol resulted in a 100% mortality (12 out of 12 animals died), brain hemorrhaging,
and stroke ... 7. CA Camargo, Jr., Moderate alcohol consumption and stroke ...

Role of Magnesium and Calcium in Alcohol-Induced Hypertension and Strokes as Probed by In Vivo … -
BM Altura, BT Altura - Alcoholism: Clinical and Experimental Research, 1994 - Blackwell Synergy
... 5-20). The risk for developing cerebral vascular diseases, such as stroke,
clearly increases with increasing alcohol consumption. ...

Alcohol withdrawal syndromes -
RC Turner, PR Lichstein, JG Peden, JT Busher, LE … - Journal of General Internal Medicine, 1989 - Springer
... weeks or longer after the discontinuation of alcohol consumption. ... fluid to rule out
hemorrhaging or a ... alter the clinical presentation of alcohol withdrawal and ...

Pyrrolidine Dithiocarbamate Attenuates Alcohol-Induced Leukocyte?Endothelial Cell Interaction and … -
BM Altura, A Gebrewold - Alcohol, 1998 - Elsevier
... dithiocarbamate administration attenuates spasm, rupture, hemorrhaging, and leukocyte
rolling ... have reported, recently, that alcohol consumption increases the ...

… nuclear factor-kappa B in cerebral vascular smooth muscle: relation to alcohol-induced brain injury … -
BM Altura, A Gebrewold, A Zhang, BT Altura - Neuroscience Letters, 2002 - Elsevier
... walls, microvessel rupture and some focal hemorrhaging [2, 3 ... 1 and 8]. Several
investigators have reported, recently, that alcohol consumption clearly alters ...

Source: Google Scholar
 

Does Alcohol Or Aspirin Consumption Increase Hemorrhaging In TBI Patients?

Article Date: 22 Apr 2007 - 0:00 PDT
An estimated 1.5 million people in the United States incur a traumatic brain injury (TBI) every year and 60,000 people die annually from these injuries. TBI is the ultimate cause of death in 40 percent of all fatal trauma cases. TBI may result from a direct blow to the brain or from the secondary effects of head trauma such as bleeding, swelling, decreased oxygen, or increased pressure on the brain. Intracranial hemorrhage (ICH) or bleeding inside the head is the cause of death in 70-80 percent of patients presenting with TBI.

ICH increases the risk of brain damage, which can lead to serious residual neurological disabilities in surviving patients. Every year, 80,000 to 90,000 people experience the onset of long-term or lifelong disabilities associated with TBI. In the United States today, there are currently as many as 5.3 million TBI survivors living with these disabilities.

There have been many studies dedicated to predicting overall clinical outcome in TBI patients. The factors which have been identified thus far are age, level of consciousness on first admission to the hospital, and degree of injury on computed tomography (CT) scanning. It is known that up to 50 percent all cases of ICH can increase with time, resulting in worsening neurological status and appearance on CT scan.

Article continues below and (thank you)
 
More than half of the patients brought to the hospital with TBI are intoxicated and many have cardiovascular disease requiring them to be on blood-thinners such as aspirin. Yet no prior studies have examined the potential effects of alcohol and aspirin consumption on worsening ICH in patients with TBI. Researchers at Elmhurst Hospital Center performed a one-year observational study on 150 patients treated at this Level 1 Trauma Center.

The results of this study, Effect of Alcohol and Aspirin Consumption on Worsening Intracranial Hemorrhage after Acute Head Injury, will be presented by Arien J. Smith, MD, 3:00 to 3:15 p.m. on Monday, April 16, 2007, during the 75th Annual Meeting of the American Association of Neurological Surgeons in Washington, D.C. Co-authors are Scott Meyer, MD, Harshipal Singh, MD, Jamie S. Ullman, MD, Brian Snyder, MD, and Ronit Gilad, MD. This research is being honored with the NovoNordisk Neurocritical Care Award.

Aspirin thins the blood, and reduces the risk of clots forming in key blood vessels, yet can cause bleeding problems in people with certain conditions Theoretically, TBI patients who are aspirin users could be prime candidates at risk for increased hemorrhaging associated with aspirin consumption.

When used in excess, alcohol damages brain structure and function. Besides the acute effects of alcohol consumption on the neurological function of the brain, there are physical changes that may result from moderate to heavy drinking of long duration. One concern is brain atrophy, which leaves more room inside the cranium for blood to collect during a brain injury. Alcohol weakens the walls of blood vessels and makes them more susceptible to rupture and bleeding. It is theorized that the combination of these factors can lead to an increase of ICH.

The study included 150 patients with a mean age of 49, admitted to the hospital with ICH after acute TBI. All pertinent patient information including history of blood-thinner usage was recorded. Initial alcohol levels were measured in all patients suspected of intoxication. Other labs were drawn including those used to assess the clotting ability of the blood. All patients underwent two sequential CT scans within 6-12 hours after admission. The CT scans were evaluated by the investigative team and the on-call radiologist for worsening brain hemorrhage. High blood alcohol levels were present in 56.2 percent of the patients. Patients taking aspirin comprised 8.2 percent of this study population.

"Interestingly, we found that neither alcohol nor aspirin were significantly associated with worsening ICH. However increasing age was significantly correlated with worsening hemorrhage," stated Dr. Smith. Overall outcome was negatively associated with worsening ICH and was measured by mortality (3 percent) and discharges to home (78.1 percent), a rehabilitation center (16.4 percent), or a skilled nursing facility (2.3 percent).

Founded in 1931 as the Harvey Cushing Society, the American Association of Neurological Surgeons (AANS) is a scientific and educational association with more than 6,800 members worldwide. The AANS is dedicated to advancing the specialty of neurological surgery in order to provide the highest quality of neurosurgical care to the public. All active members of the AANS are certified by the American Board of Neurological Surgery, the Royal College of Physicians and Surgeons (Neurosurgery) of Canada or the Mexican Council of Neurological Surgery, AC. Neurological surgery is the medical specialty concerned with the prevention, diagnosis, treatment and rehabilitation of disorders that affect the entire nervous system, including the spinal column, spinal cord, brain and peripheral nerves.

American Association of Neurological Surgeons (AANS)
5550 Meadowbrook Dr.
Rolling Meadows, IL 60008
United States
http://www.aans.org
 
 
 
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