Iconocast Logo

Welcome To Iconocast

How to add a URL link from your web site to the Iconocast web sites

Virtual tour of Southern California


Recent News and Articles on the Keywords: leukemia protein + leukemia + protein  Related to the article below (Last Update: 12/1/2008)

 News results: Standard Version | Text Version | Image Version Results 1 - 10 of about 92 for leukemia protein leukemia protein. (0.52 seconds) 
Recent
Archives
  • All dates
  • 2007-08
  • 2006
  • 2005
  • 2004
  • 2000-03

 Sorted by relevance   Sort by date   Sort by date with duplicates included 
Moving Flow Cytometry Beyond Core Facilities
Genetic Engineering News (press release), NY -
Applications in clinical diagnostics include the diagnosis of infectious diseases and evaluation of lymphoma, leukemia, autoimmune, hematologic, ...
Genta - Waiting For Genasense To Make Sense
Trading Markets (press release), CA -
... Chronic Lymphocytic Leukemia. Genasense, known generically as Oblimersen Sodium, is an antisense drug, which works by blocking a protein called Bcl-2, ...OTC:GNTA
Astex presents updates on AT7519 and AT9283 at the American ...
PharmaLive.com (press release), PA - 37 minutes ago
Together the data suggest AT7519 offers a promising treatment strategy for patients with advanced B-cell leukemia and lymphoma.

Scientist
Courtesy of John King
Scientist, UK - 56 minutes ago
Jonas knew King from the fisherman's frequent trips to Seattle during the off-seasons, and had been successful in treating feline leukemia using Protein A. ...
Restoring GABAergic Signaling and Neuronal Synchrony in Schizophrenia
Am J Psychiatry (subscription) -
(In contrast, GABA B receptors, which are the target of the muscle relaxant baclofen, belong to the group of G-protein coupled receptors. ...
Ipsogen Launches a New Test to Determine Tumor HER2 Status and ...
MarketWatch - Nov 23, 2008
With more than 60 tests already used routinely worldwide for the diagnosis, prognosis and follow-up of thousands of patients with leukemia, Ipsogen is now ...
SU research team makes leukemia breakthrough
SU The Daily Orange (subscription), NY - Nov 12, 2008
Cosgrove and his team found that the mixed lineage leukemia protein, an enzyme in white blood cells, works at a faster than normal pace in leukemia patients ...
BioReliance Introduces New Protein Array Platform -- ReliArray(TM)
MarketWatch - Nov 7, 2008
... simian immunodeficiency virus and simian T-cell lymphotropic/leukemia virus. Each protein array slide contains a collection of microscopic protein ...
Scientists develop peptide that converts Bcl-2 protein from a ...
News-Medical.net, Australia - Nov 25, 2008
Linda Wolff, a leukemia researcher at the National Institutes of Health's Center for Cancer Research in Bethesda, Md., said the researchers' discovery is ...
UCR study: Eating fruits, vegetables boosts ability to fight cancer
Press-Enterprise, CA - Nov 28, 2008
Researchers have shown that apigenin has inhibited tumor growth in several kinds of cancer cells, including breast, colon, skin, thyroid, leukemia and ...
Source: Google News


 

Recent News and Articles on the Keywords: protein + leukemia + 3,520,000  Related to the article below (Last Update: 8/5/2008)

Leukemia Journal Publishes Results from Darinaparsin Study
MarketWatch -
... certain leukemia cells that are resistant to inorganic arsenic (arsenic trioxide--ATO) because they express a drug resistance protein (MRP1/ABCC1). ...
Author : The Leukemia & Lymphoma Society
Earthtimes (press release), UK -
The cell identity maintenance process involves a cellular memory mechanism that packages genes into specialized DNA-protein structures, called chromatin. ...
Market Report -- In Play (ZIOP)
MSN Money -
... certain leukemia cells that are resistant to inorganic arsenic (arsenic trioxide--ATO) because they express a drug resistance protein (MRP1/ABCC1). ...ZIOP
Tumor-inhibiting Protein Could Be Effective In Treating Leukemia
Science Daily (press release) - Jul 15, 2008
... a tumor-inhibiting novel protein discovered by Temple University researchers, may also have a role as a new therapeutic application in treating leukemia ...
Turned-off cannabinoid receptor turns on colorectal tumor growth
Hindu, India - Aug 3, 2008
... for some types of leukemia, removed the methyl groups, restoring gene expression in 7 of 8 cell lines and full expression of CB1 protein in three lines. ...
Cheating athletes turn to gene doping
Palm Beach Post,  United States -
A group of about a dozen boys suffering from "Bubble Boy" syndrome responded positively to the process at first before some developed leukemia and died. ...
SuperGen Reports 2008 Second Quarter Financial Results
MSN Money -
SGI-1776 induces cell cycle arrest, dose dependent apoptosis and a reduction in phospho-BAD levels in leukemia and lymphoma cell lines. ...SUPG
Angiogenesis Inhibitor Protein Provides a new Approach in Treating ...
Medi News Direct, India - Jul 24, 2008
The use of this novel protein could therefore be a major breakthrough in bringing about better treatment outcomes in leukemia. 1. ...
Aegera Initiates a Fifth Phase 1 and 2 Clinical Trial for AEG35156
MarketWatch - Jul 31, 2008
... a key member of the Inhibitor of Apoptosis protein family. The study, made possible, in part, by funding from The Leukemia & Lymphoma Society, ...
Immunotherapy With Leukemia-cell-derived Heat Shock Protein 70 ...
Medical News Today (press release), UK - Jul 24, 2008
This study established a mouse model after bone marrow transplant and found that the immunization of mice with leukemia-cell-derived heat shock protein 70 ...
Source: Google News

… of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. -
L Chen, G Widhopf, L Huynh, L Rassenti, KR Rai, A … - Blood, 2002 - ncbi.nlm.nih.gov
... We examined isolated leukemia B cells of patients with chronic lymphocytic leukemia
(CLL) for expression of zeta-associated protein 70 (ZAP-70). ...

High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to … -
L Campos, JP Rouault, O Sabido, P Oriol, N Roubi, … - Blood, 1993 - ncbi.nlm.nih.gov
1993 Jun 1;81(11):3091-6. Click here to read High expression of bcl-2 protein in
acute myeloid leukemia cells is associated with poor response to chemotherapy. ...

A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human Leukemia -
V Lacronique, A Boureux, V Della Valle, H Poirel, … - Science, 1997 - sciencemag.org
... Reports. A TEL-JAK2 Fusion Protein with Constitutive Kinase Activity in Human
Leukemia. Virginie Lacronique, Anthony Boureux, V?ronique ...

… ): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia -
N Carpino, D Wisniewski, A Strife, D Marshak, R … - Cell, 1997 - ncbi.nlm.nih.gov
... Click here to read Links. p62(dok): a constitutively tyrosine-phosphorylated,
GAP-associated protein in chronic myelogenous leukemia progenitor cells. ...

The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and … -
F Grignani, PF Ferrucci, U Testa, G Talamo, M … - Cell, 1993 - cell.com
... Article. The acute promyelocytic leukemia-specific PML-RARa fusion protein inhibits
differentiation and promotes survival of myeloid precursor cells. ...

An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase …
JB Konopka, SM Watanabe, ON Witte - Cell, 1984 - ncbi.nlm.nih.gov
Cell. 1984 Jul;37(3):1035-42. Click here to read An alteration of the human c-abl
protein in K562 leukemia cells unmasks associated tyrosine kinase activity. ...

… 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein -
GQ Daley, D Baltimore - Proceedings of the National Academy of Sciences of the …, 1988 - pubmedcentral.nih.gov
... Copyright notice. Transformation of an interleukin 3-dependent hematopoietic cell
line by the chronic myelogenous leukemia-specific P210bcr/abl protein. ...

The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene -
Y Ben-Neriah, GQ Daley, AM Mes-Masson, ON Witte, D … - Science, 1986 - sciencemag.org
... By analogy to the gag/abl fusion protein of Abelson murine leukemia virus, the
replacement of amino terminal c-abl sequences by bcr sequences in P210 may ...

Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1 … -
DY Jin, F Spencer, KT Jeang - Cell, 1998 - ncbi.nlm.nih.gov
... 1: Cell. 1998 Apr 3;93(1):81-91. Click here to read Links. Human T cell leukemia
virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1. ...

Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear … -
HP Bogerd, RA Fridell, RE Benson, J Hua, BR Cullen - Mol. Cell. Biol, 1996 - pubmedcentral.nih.gov
... Abstract. The Rex protein of human T-cell leukemia virus type 1, like the functionally
equivalent Rev protein of human immunodeficiency virus type 1, contains a ...

Source: Google Scholar
 

A Protein That Promotes Leukemia

Article Date: 13 Mar 2007 - 4:00 PDT
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells. CDX2 regulates the expression of a number of genes that encode members of the HOX family of proteins, which might provide a new set of targets for the treatment of individuals with AML.

In the study, which appears online in advance of publication in the April print issue of the Journal of Clinical Investigation, Stefan Fröhling and colleagues show that the gene encoding CDX2 is expressed in 90% of the patients with AML that they analyzed. Moreover, reducing the amount of CDX2 in human AML cell lines decreased their ability to proliferate, indicating that CDX2 has a causal role in the pathogenesis of AML. Further evidence of this was provided by the observation that mouse hematopoietic cells engineered to express CDX2 were induced to proliferate and were able to cause full-blown AML when transplanted into mice. Expression of CDX2 in the mouse hematopoietic cells induced altered expression of a number of genes that encode HOX family of proteins, leading the authors to conclude that aberrant expression of CDX2 drives the dysregulated HOX gene expression observed in most individuals with AML.

Article continues below and (thank you)

 
TITLE: The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis

AUTHOR CONTACT:
Stefan Fröhling
Brigham and Women's Hopsital, Harvard Medical School, Boston, Massachusetts, USA

Contact: Karen Honey
Journal of Clinical Investigation
 

Vision correction may raise fall risk in elderly

Last Updated: 2007-03-12 13:59:45 -0400 (Reuters Health)

NEW YORK (Reuters Health) - Helping frail older people to see more clearly may put them at increased risk of falls, according to a new study from Australia.

This could be because getting used to a new eyeglass prescription may throw people off balance, Dr. Robert G. Cumming, at Concord Hospital in New South Wales, and colleagues suggest. Whatever the explanation, they say the findings indicate that programs aimed at preventing falls among the elderly by improving their vision should be put on hold for now.

One previous study found that removing cataracts -- which allows people to see contrasts more clearly -- reduced falls among elderly people, but another found no effect, Cumming and his team note in the Journal of the American Geriatrics Society.

To better understand how improving elderly people's vision might affect fall risk, the researchers randomly assigned 616 men and women aged 70 and older to receive vision and eye exams, along with appropriate treatment, or to receive their usual care.

In the treatment group, 92 people got new eyeglasses, 24 had a home visit with an occupational therapist, 17 received glaucoma treatment, and 15 had cataract surgery.

However, during the following year, 65 percent of people in the treatment group fell at least once, compared to 50 percent of those in the control group. Thirty-one fractures occurred in the treatment group, while there were 18 among the untreated participants.

Overall, the men and women given vision treatment were 57 percent more likely to fall and 74 percent more likely to sustain fractures than those in the control group.

One explanation for the findings is that study participants needed a long time to adjust to new eyeglasses, Cumming and his team said. It's also possible, they add, that people in the treatment group who were given a clean bill of visual health became more active and took "unaccustomed risks."

While the findings must be confirmed by other researchers, Cumming and his team add, "it may be premature to implement the wide range of vision-related interventions to prevent falls proposed by others."

They also advise that eye care providers working with elderly people should be aware that their patients may be more prone to fall after receiving a new set of glasses. "They should prescribe conservatively and give appropriate advice about the need for caution during adaptation to new eyeglasses," the team concludes.

SOURCE: Journal of the American Geriatrics Society, February 2007.

Copyright © 2007 Reuters Limited. All rights reserved. Republication or redistribution of Reuters content, including by framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in the content, or for any actions taken in reliance thereon. Reuters and the Reuters sphere logo are registered trademarks and trademarks of the Reuters group of companies around the world.

 
Google
Web www.iconocast.com
 
 
Source for News : URL: http://www.medicalnewstoday.com and Reuters
Continue News With: News2 ; News3 ; News4 ; News5 ; News6 ; News7 ; News8 ; News9 ; News9A


ADVERTISEMENT

Iconocast is about learning and teaching without borders; we offer eMarketing, Internet Advertising, Internet Marketing, Search Engine Optimization, Search Engine Marketing, Online Branding, and eMarketing News Services.

 

Iconocast Home Page

 © 2002-2006

Keywords:

Contact Iconocast