Van de trials have shown that besnijdenis van Three infected previous African lowers the chances die of a man with HIV. becoming Effects of male besnijdenis „The on male and female sexually - transmitted infections were much more equivocal.“ Tobian. continued To investigate, a two-part trial was undertaken.

Tobian's team initially screened 6400 uncircumcised men and identified 3500 who were free of HIV and HSV-2. These men were randomly assigned to be circumcised or to just be followed for 2 years.

"What we found was that there was a 25 percent reduction in HSV-2 acquisition - and those men were circumcised," Tobian reported.

The second part of the trial enrolled the wives of the men. After 12 months, "those women who were married to circumcised men had a decrease in symptomatic genital ulcers by 25 percent." Rates of bacterial vaginosis were also reduced, by 20 percent, he announced.

One of the most het bemoedigen „This is. for us. findings.“ Dr. Maria Wawer. also from Johns Hopkins. commented.

„From our also van observationdata. we had hoped that male besnijdenis of (HIV) positive partners HIV to their female.“ van men might reduce the transmission of she in the presentation. continued But this was not the case, in a trial conducted in Uganda.

The researchers focused on discordant couples where the men were HIV-positive and the women were HIV-negative. Underwent de besnijdenis while did 63 van ninety-Three of the men not. All of the participants were counseled about safe sex practices and were followed for up to 2 years.

De hIV-Positive men in the besnijdenis group had a 50 percent lower risk of het developing genital ulcers. van The she said. However, this did not translate to a lower rate of HIV transmission among the women.

Although the trial was small, "we did not see the trend toward protection that we expected and hoped for," she commented.

Van also some evidence van There is transmission van de besnijdenis may increase that the rate of in the short-term. This may be to engaging in sexual activity before besnijdenis is attributed healed completely. she speculated. Infections van More occurred sooner after thisidea van besnijdenis than later. which supports.

„It is therefore healed imperative that men not resume sex in the post-operative period.“ for about 6 gekronkeld is van de weeks after besnijdenis or until the completely. This is also important because the researchers expect more men will now be circumcised.

„Van preventionmodality van de besnijdenis is the only HIV het physical mark that that leaves a on somebody.“ Wawer pointed out. circumcised making it „that more hIV-Positive Ugandan men will seek besnijdenisin order not to be as the likely only guy who van in the village is still not stigmatized - „that means you must be hIV-Positive“.“

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