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Double risk of colorectal poliepen van Smoking can

M.D. (Feb. 1. 2008) van Bethesda. - Smokers have a two-fold increased risk of developing colorectal poliepen. the suspected het underlying cause of most colorectal study (CRC) cancers. according to a published in official journal of the American Gastroenterological Association Institute van Gastroenterology. (AGA) the.

The results from this meta-analysis showed pooled risk estimates of 2.14 for current versus never smokers, 1.82 for ever versus never smokers and 1.47 for former versus never smokers. Smokers van Ever had a additional van 13 percent het increasing risk of poliepen for every 10 pack-years smoked in comparison to never smokers. Smoked individual who van For example. an one pack of cigarettes per day for 50 day for 25 van years or two packs a probability van years had almost twice the for de developing colorectal poliepen to an individual who never smoked. compared

Van thismeta-analysis van The results of attributed meest suggest that approximately 20 percent to 25 percent may be van of colorectal poliepen to het smoking. De poliepen. van Risk was significantly greater for high-risk het indicating that het smoking may into van transformation of poliepen van be important for the cancer. The study findings are potentially important for determining the age of onset of colorectal cancer screening.

"While the harmful health effects of tobacco smoking are well-known, smoking has not been considered so far in the stratification of patients for CRC screening. Findings die van Our could support the recommended age for smokers to receive colorectal cancer die.“ said Albert B. Lowenfels. seniorauthor of the study. from New York Medical College. Valhalla. New York screening van het M.D. lowering

At present, evidence of a role for tobacco smoking on the development of CRC is still controversial. Explanation could be that CRC develops much later in life than poliepen van One; the long latency period makes it difficult to establish a firm link between smoking and CRC.

The study was performed at the Division of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy where the lead author, Edoardo Botteri, performed the analysis based on the combined evidence from 42 independent observational studies.

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About the AGA Institute

The American Gastroenterological Association (AGA) is dedicated to the mission of advancing the science and practice of gastroenterology. Founded in 1897, the AGA is one of the oldest medical-specialty societies in the U.S. Comprised of two non-profit organizations - the AGA and the AGA Institute - our more than 16,000 members include physicians and scientists who research, diagnose and treat disorders of the gastrointestinal tract and liver. The AGA, a 501(c6) organization, administers all membership and public policy activities, while the AGA Institute, a 501(c3) organization, runs the organization's practice, research and educational programs. On a monthly basis, the AGA Institute publishes two highly-respected journals, Gastroenterology and Clinical Gastroenterology and Hepatology. The organization's annual meeting is Digestive Disease Week®, which is held each May and is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Information. please visit www.gastro.org van For more.

About Gastroenterology

Gastroenterology, the official journal of the AGA Institute, is the most prominent scientific journal in the specialty and is in the top 1 percent of indexed medical journals internationally. The journal publishes clinical and basic science studies of all aspects of the digestive system, including the liver and pancreas, as well as nutrition. The journal is abstracted and indexed in Biological Abstracts, CABS, Chemical Abstracts, Current Contents, Excerpta Medica, Index Medicus, Nutrition Abstracts and Science Citation Index. Information. visit www.gastrojournal.org van For more.

 
 
 
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