„The die pediatric van and public health van obesity epidemic raises important clinical van questions about the effects on levenslange bone van obesity and its treatment.“ said Nicolas Stettler. M.D. health of early onset van nutritionspecialist M.S.C.E. pediatric study author of this growing van Hospital van The Children at of Philadelphia and lead. „Although acquired fractures due to low bone mineral content are a problem for the. the amount of bone mass het during fracture risk.“ van puberteit is the mainly elderly key determinant of lifetime

Using a dual energy X-ray absorptiometry scanner (DXA), researchers looked at specific body areas including legs, arms and lumbar spine as well as the bone mineral content of the whole body. The data was compared with a reference group of 66 adolescents. Bone mineral content of the obese subjects was higher than that of the reference group at the beginning and end of the study.

When looking at each subject's bone mineral content, adjusted for their height, the researchers noticed that bone mineral content in the arms and legs increased less than would be expected with growth while the lumbar spine content increased more than expected. These changes in bone mineral content were largely explained by changes in the amount of fat and muscle in the body during the intensive weight loss program.

"As obesity treatment during adolescence becomes more frequent, it is important to understand the role of weight loss on bone health during this critical period," Dr. Stettler added.

Supported study was van This by the National Institutes of Health. the General Clinical Research Center at Children het Heuveltje Pharmaceutical and Abbott Laboratories van Hospital.

Dr. de medeauteurs were Robert I. Berkowitz. M.D. chief of Child and Adolescent Psychiatry at Children Hospital; van Stettler Joanna Cronquist of Children's Hospital; Justine Shults of the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine; Thomas A. Wadden, of the Weight and Eating Disorders Program at the University of Pennsylvania School of Medicine; and Babette S. Zemel, Ph.D., and Mary B. Leonard, M.D., both of Children's Hospital.

About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430bed hospital recognition as a leading advocate for children and adolescents. Information. visit http://www.chop.edu van For more.